[F1ANNEX U.K. EXPLANATION OF THE SECTIONS USED FOR THE DEFINITION AND CLASSIFICATION OF CASES

ACQUIRED IMMUNODEFICIENCY SYNDROME (AIDS) AND HUMAN IMMUNODEFICIENCY VIRUS (HIV) INFECTION U.K.

Clinical criteria (AIDS) U.K.

Any person who has any of the clinical conditions as defined in the European AIDS case definition for:

Laboratory criteria (HIV) U.K.

  • Adults, adolescents and children aged = 18 months

    At least one of the following three:

    • Positive result of a HIV screening antibody test or a combined screening test (HIV antibody and HIV p24 antigen) confirmed by a more specific antibody test (e.g. Western blot)

    • Positive result of 2 EIA antibody test confirmed by a positive result of a further EIA test

    • Positive results on two separate specimens from at least one of the following three:

      • Detection of HIV nucleic acid (HIV-RNA, HIV-DNA)

      • Demonstration of HIV by HIV p24 antigen test, including neutralisation assay

      • Isolation of HIV

  • Children aged < 18 months

    Positive results on two separate specimens (excluding cord blood) from at least one of the following three:

    • Isolation of HIV

    • Detection of HIV nucleic acid (HIV-RNA, HIV-DNA)

    • Demonstration of HIV by HIV p24 antigen test, including neutralisation assay in a child =1 month of age

Epidemiological criteria U.K.

NA

Case classification U.K.

A. Possible case U.K.

NA

B. Probable case U.K.

NA

C. Confirmed case U.K.
  • HIV infection

    Any person meeting the laboratory criteria for HIV infection

  • AIDS

    Any person meeting the clinical criteria for AIDS and the laboratory criteria for HIV infection]

(1)

[F1European Centre for the Epidemiological Monitoring of AIDS. 1993 revision of the European AIDS surveillance case definition. AIDS Surveillance in Europe, Quarterly Report 1993; No 37: 23-28

(2)

European Centre for the Epidemiological Monitoring of AIDS. European case definition for AIDS surveillance in children — revision 1995. HIV/AIDS Surveillance in Europe, Quarterly Report 1995; No 48: 46-53]