[F1 ANNEX U.K. EXPLANATION OF THE SECTIONS USED FOR THE DEFINITION AND CLASSIFICATION OF CASES

Textual Amendments

F1 Substituted by Commission Decision of 28 April 2008 amending Decision 2002/253/EC laying down case definitions for reporting communicable diseases to the Community network under Decision No 2119/98/EC of the European Parliament and of the Council (notified under document number C(2008) 1589) (Text with EEA relevance) (2008/426/EC).

AVIAN INFLUENZA A/H5 OR A/H5N1 IN HUMANS U.K.

Clinical criteria U.K.

Any person with one of the following two:

• Fever AND signs and symptoms of acute respiratory infection

• Death from an unexplained acute respiratory illness

Laboratory criteria U.K.

At least one of the following three:

• Isolation of influenza A/H5N1 from a clinical specimen

• Detection of influenza A/H5 nucleic acid in a clinical specimen

• Influenza A/H5 specific antibody response (fourfold or greater rise or single high titre)

Epidemiological criteria U.K.

At least one of the following four:

• Human to human transmission by having been in close contact (within one metre) to a person reported as probable or confirmed case

• Laboratory exposure: where there is a potential exposure to influenza A/H5N1

• Close contact (within one metre) with an animal with confirmed A/H5N1 infection other than poultry or wild birds (e.g. cat or pig)

• Reside in or have visited an area where influenza A/H5N1 is currently suspected or confirmed (1) AND at least one of the following two:

  • Having been in close contact (within one metre) with sick or dead domestic poultry or wild birds (2) in the affected area

  • Having been in a home or a farm where sick or dead domestic poultry have been reported in the previous month in the affected area

Case classification U.K.

A. Possible case U.K.

Any person meeting the clinical and the epidemiological criteria

B. Probable case U.K.

Any person with a positive test for influenza A/H5 or A/H5N1 performed by a laboratory which is not a National Reference Laboratory participating in the EU Community Network of Reference Laboratories for human influenza (CNRL)

C. Nationally confirmed case U.K.

Any person with a positive test for influenza A/H5 or A/H5N1 performed by a National Reference Laboratory participating in the EU Community Network of Reference Laboratories for human influenza (CNRL)

D. WHO confirmed case U.K.

Any person with a laboratory confirmation by a WHO Collaborating Centre for H5]

(1)

[F1 See World isOrganisation for Animal Health — OIE — and European Commission (SANCO) Animal Disease Notification System (ADNS), available at: http://www.oie.int/eng/en_index.htm and http://ec.europa.eu/food/animal/diseases/adns/index_en.htm#)

(2)

This does not include seemingly well birds that have been killed, for example by hunting.]

Textual Amendments

F1 Substituted by Commission Decision of 28 April 2008 amending Decision 2002/253/EC laying down case definitions for reporting communicable diseases to the Community network under Decision No 2119/98/EC of the European Parliament and of the Council (notified under document number C(2008) 1589) (Text with EEA relevance) (2008/426/EC).