Council Directive of 23 April 1990 on the contained use of genetically modified micro-organisms (90/219/EEC) (repealed)

  1. Introductory Text

  2. Article 1.. . . . . . . . . ....

  3. Article 2.. . . . . . . . . ....

  4. Article 3.. . . . . . . . . ....

  5. Article 4.. . . . . . . . . ....

  6. Article 5.. . . . . . . . . ....

  7. Article 6.. . . . . . . . . ....

  8. Article 7.. . . . . . . . . ....

  9. Article 8.. . . . . . . . . ....

  10. Article 9.. . . . . . . . . ....

  11. Article 10.. . . . . . . . . ....

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  13. Article 12.. . . . . . . . . ....

  14. Article 13.. . . . . . . . . ....

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  16. Article 15.. . . . . . . . . ....

  17. Article 16.. . . . . . . . . ....

  18. Article 17.. . . . . . . . . ....

  19. Article 18.. . . . . . . . . ....

  20. Article 19.. . . . . . . . . ....

  21. Article 20.. . . . . . . . . ....

  22. Article 20a.. . . . . . . . . ....

  23. Article 21.. . . . . . . . . ....

  24. Article 22.. . . . . . . . . ....

  25. Article 23.. . . . . . . . . ....

    1. ANNEX I

      1. PART A

      2. PART B

    2. ANNEX II

      1. PART A

      2. PART B

        1. Criteria establishing the safety of GMMs for human health and...

          1. 1. INTRODUCTION

          2. 2. GENERAL CRITERIA

            1. 2.1. Strain verification/authentication

            2. 2.2. Documented and established evidence of safety

            3. 2.3. Genetic stability

          3. 3. SPECIFIC CRITERIA

            1. 3.1. Non-pathogenic

              1. 3.1.1. Non-toxigenic

              2. 3.1.2. Non-allergenic

            2. 3.2. No harmful adventitious agents

            3. 3.3. Transfer of genetic material

            4. 3.4. Safety for the environment in the event of a significant...

        2. Guidance notes supplementing part B of Annex II to Directive...

          1. INTRODUCTION

          2. 1. GENERAL CRITERIA

            1. 1.1. Strain verification/authentication

            2. 1.2. Documented and established safety

            3. 1.3. Genetic stability

          3. 2. SPECIFIC CRITERIA

            1. 2.1. Non-pathogenic

              1. 2.1.1. Non-toxigenic

              2. 2.1.2. Non-allergenic

            2. 2.2. No harmful adventitious agents

            3. 2.3. Transfer of genetic material

            4. 2.4. Safety for the environment in the event of an escape...

              1. 2.4.1. Organism survival

              2. 2.4.2. Dispersal

              3. 2.4.3. Organism establishment in the environment

              4. 2.4.4. Transfer of genetic material

        3. APPENDIX 1

          1. Definitions of terms used in this document

      3. PART C

    3. ANNEX III

      PRINCIPLES TO BE FOLLOWED FOR THE ASSESSMENT REFERRED TO IN ARTICLE 5(2)

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      2. . . . . . . . . . ....

      3. A. ELEMENTS OF ASSESSMENT

        1. 1. . . . . . . . . . ....

        2. 2. . . . . . . . . . ....

      4. B. PROCEDURE

        1. 3. . . . . . . . . . ....

        2. 4. . . . . . . . . . ....

        3. 5. . . . . . . . . . ....

        4. 6. . . . . . . . . . ....

        5. 7. . . . . . . . . . ....

        6. 8. . . . . . . . . . ....

        7. 9. . . . . . . . . . ....

    4. ANNEX IV

      CONTAINMENT AND OTHER PROTECTIVE MEASURES

      1. General principles

        1. 1. . . . . . . . . . ....

        2. 2. . . . . . . . . . ....

        3. 3. . . . . . . . . . ....

      2. Table I A Containment and other protective measures for laboratory activities

      3. Table I B Containment and other protective measures for glasshouses and growth-rooms

      4. Table I C Containment and other protective measures for activities in animal units...

      5. Table II Containment and other protective measures for other activities

    5. ANNEX V

      1. PART A

      2. PART B

      3. PART C