Amendments to the Annexes to this Directive, to be made in the light of developments in scientific or technical knowledge, shall be adopted in accordance with the procedure laid down in Article 16a of Directive 77/93/EEC. In the case of the methods laid down in Annex II and the measures in paragraphs 4.1 and 4.2 of Annex VI to this Directive a report shall be prepared by the Commission reviewing these methods and measures in the light of experience gained and the report shall be submitted to the Committee before 1 January 2002.