VI.TOXICOLOGICAL AND METABOLIC STUDIESU.K.
1.Neurotoxicity studyU.K.
If the active substance is an organophosphorus compound or if there are any other indications that the active substance may have neurotoxic properties then neurotoxicity studies will be required. The test species is the adult hen unless another test species is justified to be more appropriate. If appropriate, delayed neurotoxicity tests will be required. If anticholine esterase activity is detected a test for response to reactivating agents should be considered
2.Toxic effects on livestock and petsU.K.
3.Studies related to the exposure of the active substance to humansU.K.
4.Food and feedingstuffsU.K.
If the active substance is to be used in preparations for use where food for human consumption is prepared, consumed or stored, or where feedingstuff for livestock is prepared, consumed or stored the tests referred to in Section XI, part 1 shall be required