Member States shall ensure that:

1. (a)

   laboratories and establishments in which live foot-and-mouth disease virus, its genome, antigens or vaccines produced from such antigens are handled for research, diagnosis or manufacture are strictly controlled by the competent authorities;

2. (b)

   the handling of live foot-and-mouth disease virus for research and diagnosis is carried out only in approved laboratories listed in Part A of Annex XI;

3. (c)

   the handling of live foot-and-mouth disease virus for the manufacturing of either inactivated antigens for the production of vaccines or vaccines and related research is carried out only in the approved establishments and laboratories listed in Part B of Annex XI;

4. (d)

   the laboratories and establishments referred to in points (b) and (c) are operated at least according to the bio-security standards set out in Annex XII.