http://www.legislation.gov.uk/id/eur/1990/2377

F1ANNEX ILIST OF PHARMACOLOGICALLY ACTIVE SUBSTANCES FOR WHICH MAXIMUM RESIDUE LIMITS HAVE BEEN FIXED

Annotations:

Amendments (Textual)

Substituted by Commission Regulation (EC) No 508/1999 of 4 March 1999 amending Annexes I to IV to Council Regulation (EEC) No 2377/90 laying down a Community procedure for the establishment of maximum residue limits of veterinary medicinal products in foodstuffs of animal origin.

1.Anti-infectious agents

1.1.Chemotheurapeutics

1.1.1.Sulfonamides

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues	Other provisions
All substances belonging to the sulfonamide group	Parent drug	All food-producing species	100 μg/kg	Muscle	The combined total residues of all substances within the sulfonamide group should not exceed 100 μg/kg
			100 μg/kg	Fat
			100 μg/kg	Liver
			100 μg/kg	Kidney
		Bovine, ovine, caprine	100 μg/kg	Milk

1.1.2.Diamino pyrimidine derivatives

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues	Other provisions
Baquiloprim	Baquiloprim	Bovine	10 μg/kg	Fat
			300 μg/kg	Liver
			150 μg/kg	Kidney
			30 μg/kg	Milk
		Porcine	40 μg/kg	Skin and fat
			50 μg/kg	Liver
			50 μg/kg	Kidney
F3Trimethoprim	Trimethoprim	All food producing species except equidae	50 μg/kg	Fat8	Not for use in animals from which eggs are produced for human consumption
			50 μg/kg	Muscle 9
			50 μg/kg	Liver
			50 μg/kg	Kidney
			50 μg/kg	Milk
		Equidae	100 μg/kg	Muscle
			100 μg/kg	Fat
			100 μg/kg	Liver
			100 μg/kg	Kidney
For porcine and poultry species this MRL relates to ‘skin and fat in natural proportions’.
For fin fish this MRL relates to ‘muscle and skin in natural proportions’.

1.2.Antibiotics

1.2.1.Penicillins

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues
Amoxicyllin	Amoxicyllin	All food-producing species	50 μg/kg	Muscle
			50 μg/kg	Fat
			50 μg/kg	Liver
			50 μg/kg	Kidney
			4 μg/kg	Milk
Ampicillin	Ampicillin	All food-producing species	50 μg/kg	Muscle
			50 μg/kg	Fat
			50 μg/kg	Liver
			50 μg/kg	Kidney
			4 μg/kg	Milk
Benzylpenicillin	Benzylpenicillin	All food-producing species	50 μg/kg	Muscle
			50 μg/kg	Fat
			50 μg/kg	Liver
			50 μg/kg	Kidney
			4 μg/kg	Milk
Cloxacillin	Cloxacillin	All food-producing species	300 μg/kg	Muscle
			300 μg/kg	Fat
			300 μg/kg	Liver
			300 μg/kg	Kidney
			30 μg/kg	Milk
Dicloxacillin	Dicloxacillin	All food-producing species	300 μg/kg	Muscle
			300 μg/kg	Fat
			300 μg/kg	Liver
			300 μg/kg	Kidney
			30 μg/kg	Milk
F6Nafcillin	Nafcillin	All ruminants10	300 μg/kg	Muscle
			300 μg/kg	Fat
			300 μg/kg	Liver
			300 μg/kg	Kidney
			30 μg/kg	Milk
Oxacillin	Oxacillin	All food-producing species	300 μg/kg	Muscle
			300 μg/kg	Fat
			300 μg/kg	Liver
			300 μg/kg	Kidney
			30 μg/kg	Milk
Penethamate	Benzylpenicillin	Bovine	50 μg/kg	Muscle
			50 μg/kg	Fat
			50 μg/kg	Liver
			50 μg/kg	Kidney
			4 μg/kg	Milk
F7		Porcine	50 μg/kg	Muscle
			50 μg/kg	Fat
			50 μg/kg	Liver
			50 μg/kg	Kidney
F8		All mammalian-food producing species	50 μg/kg	Muscle
			50 μg/kg	Fat
			50 μg/kg	Liver
			50 μg/kg	Kidney
			4 μg/kg	Milk
F9Phenoxymethylpenicillin	Phenoxymethylpenicillin	Porcine	25 μg/kg	Muscle
			25 μg/kg	Liver
			25 μg/kg	Kidney
		F5Poultry11	25 μg/kg	Muscle
			25 μg/kg	Skin + fat
			25 μg/kg	Liver
			25 μg/kg	Kidney
For intramammary use only.
Not for use in animals from which eggs are produced for human consumption.

1.2.2.Cephalosporins

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues	Other provisions
F11Cefacetrile	Cefacetrile	Bovine	125 μg/kg	Milk	For intramammary use only
F12Cefalexin	Cefalexin	Bovine	200 μg/kg	Muscle
			200 μg/kg	Fat
			200 μg/kg	Liver
			1 000 μg/kg	Kidney
			100 μg/kg	Milk
F13Cefalonium	Cefalonium	Bovine	20 μg/kg	Milk
F14Cefapirin	Sum of cephapirin and desacetylcephapirin	Bovine	50 μg/kg	Muscle
			50 μg/kg	Fat
			100 μg/kg	Kidney
			60 μg/kg	Milk
Cefazolin	Cefazolin	Bovine, ovine, caprine	50 μg/kg	Milk
F15Cefoperazone	Cefoperazone	Bovine	50 μg/kg	Milk
Cefquinome	Cefquinome	Bovine	50 μg/kg	Muscle
			50 μg/kg	Fat
			100 μg/kg	Liver
			200 μg/kg	Kidney
			20 μg/kg	Milk
F16		Porcine	50 μg/kg	Muscle
			50 μg/kg	Skin + fat
			100 μg/kg	Liver
			200 μg/kg	Kidney
F17		Equidae	50 μg/kg	Muscle
			50 μg/kg	Fat
			100 μg/kg	Liver
			200 μg/kg	Kidney
F18Ceftiofur	Sum of all residues retaining the betalactam structure expressed as desfuroylceftiofur	All mammalian food-producing species	1 000 μg/kg	Muscle
			2 000 μg/kg	Fat12
			2 000 μg/kg	Liver
			6 000 μg/kg	Kidney
			100 μg/kg	Milk
For porcine species this MRL relates to ‘skin and fat in natural proportions’.

1.2.3.Quinolones

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues	Other provisions
F3Danofloxacin	Danofloxacin	X1All food producing species except bovine, ovine, caprine, porcine and poultry	100 μg/kg	Muscle14
			50 μg/kg	Fat13
			200 μg/kg	Liver
			200 μg/kg	Kidney
		Bovine, ovine, caprine	200 μg/kg	Muscle
			100 μg/kg	Fat
			400 μg/kg	Liver
			400 μg/kg	Kidney
			30 μg/kg	Milk
		Poultry	200 μg/kg	Muscle	Not for use in animals from which eggs are produced for human consumption
			100 μg/kg	Skin and fat
			400 μg/kg	Liver
			400 μg/kg	Kidney
Difloxacin	Difloxacin	All food producing species except bovine, ovine, caprine and poultry	300 μg/kg	Muscle14
			100 μg/kg	Fat
			800 μg/kg	Liver
			600 μg/kg	Kidney
		Bovine, ovine, caprine	400 μg/kg	Muscle	Not for use in animals from which milk is produced for human consumption
			100 μg/kg	Fat
			1 400 μg/kg	Liver
			800 μg/kg	Kidney
		Porcine	400 μg/kg	Muscle
			100 μg/kg	Skin and fat
			800 μg/kg	Liver
			800 μg/kg	Kidney
		Poultry	300 μg/kg	Muscle	Not for use in animals from which eggs are produced for human consumption
			400 μg/kg	Skin and fat
			1 900 μg/kg	Liver
			600 μg/kg	Kidney
Enrofloxacin	Sum of enrofloxacin and ciprofloxacin	All food producing species except bovine, ovine, caprine, porcine, rabbits and poultry	100 μg/kg	Muscle14
			100 μg/kg	Fat
			200 μg/kg	Liver
			200 μg/kg	Kidney
		Bovine, ovine, caprine	100 μg/kg	Muscle
			100 μg/kg	Fat
			300 μg/kg	Liver
			200 μg/kg	Kidney
			100 μg/kg	Milk
		Porcine, rabbits	100 μg/kg	Muscle
			100 μg/kg	Fat13
			200 μg/kg	Liver
			300 μg/kg	Kidney
		Poultry	100 μg/kg	Muscle	Not for use in animals from which eggs are produced for human consumption
			100 μg/kg	Skin and fat
			200 μg/kg	Liver
			300 μg/kg	Kidney
Flumequine	Flumequine	All food producing species except bovine, ovine, caprine, porcine, poultry and fin fish	200 μg/kg	Muscle
			250 μg/kg	Fat
			500 μg/kg	Liver
			1 000 μg/kg	Kidney
		Bovine, porcine, ovine, caprine	200 μg/kg	Muscle
			300 μg/kg	Fat13
			500 μg/kg	Liver
			1 500 μg/kg	Kidney
			50 μg/kg	Milk
		Poultry	400 μg/kg	Muscle	Not for use in animals from which eggs are produced for human consumption
			250 μg/kg	Skin and fat
			800 μg/kg	Liver
			1 000 μg/kg	Kidney
		Fin fish	600 μg/kg	Muscle and skin in natural proportion
F20Marbofloxacin	Marbofloxacin	Bovine	150 μg/kg	Muscle
			50 μg/kg	Fat
			150 μg/kg	Liver
			150 μg/kg	Kidney
			75 μg/kg	Milk
		Porcine	150 μg/kg	Muscle
			50 μg/kg	Skin and fat
			150 μg/kg	Liver
			150 μg/kg	Kidney
F21Oxolinic acid	Oxolinic acid	Porcine	100 μg/kg	Muscle
			50 μg/kg	Skin and fat
			150 μg/kg	Liver
			150 μg/kg	Kidney
		Chicken	100 μg/kg	Muscle	Not for use in animals from which eggs are produced for human consumption
			50 μg/kg	Skin and fat
			150 μg/kg	Liver
			150 μg/kg	Kidney
		Fin fish	100 μg/kg	Muscle and skin in natural proportions
		F19All food-producing species15	100 μg/kg	Muscle13
			50 μg/kg	Fat16
			150 μg/kg	Liver
			150 μg/kg	Kidney
Sarafloxacin	Sarafloxacin	Chicken	10 μg/kg	Skin and fat
			100 μg/kg	Liver
		Salmonidae	30 μg/kg	Muscle and skin in natural proportions
For fin fish this MRL relates to ‘muscle and skin in natural proportions’.
For porcine species this MRL relates to ‘skin and fat in natural proportions’.
Not for use in animals from which milk or eggs are produced for human consumption; MRLs for fat, liver and kidney do not apply to fin fish.
For porcine and poultry species this MRL relates to ‘skin and fat in natural proportions’.

1.2.4.Macrolides

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues	Other provisions
F24Acetylisovaleryltylosin	Sum of acetyl-isovaleryltylosin and 3-O-acetyltylosin	Porcine	50 μg/kg	Muscle
			50 μg/kg	Skin and fat
			50 μg/kg	Liver
			50 μg/kg	Kidney
		F23Poultry21	50 μg/kg	Skin + fat
		F23Poultry21	50 μg/kg	Liver
F3Erythromycin	Erythromicyin A	All food producing species	200 μg/kg	Muscle 17
			200 μg/kg	Fat 18
			200 μg/kg	Liver
			200 μg/kg	Kidney
			40 μg/kg	Milk
			150 μg/kg	Eggs
Spiramycin	Sum of spiramycin and neospiramycin	Bovine	200 μg/kg	Muscle
			300 μg/kg	Fat
			300 μg/kg	Liver
			300 μg/kg	Kidney
			200 μg/kg	Milk
		Chicken	200 μg/kg	Muscle
			300 μg/kg	Skin and fat
			400 μg/kg	Liver
F25	Spiramycin 1	Porcine	250 μg/kg	Muscle
			2 000 μg/kg	Liver
			1 000 μg/kg	Kidney
F3Tilmicosin	Tilmicosin	All food producing species except poultry	50 μg/kg	Muscle 17
			50 μg/kg	Fat 18
			1 000 μg/kg	Liver
			1 000 μg/kg	Kidney
			50 μg/kg	Milk
		Poultry	75 μg/kg	Muscle	Not for use in animals from which eggs are produced for human consumption
			75 μg/kg	Sin and fat
			1 000 μg/kg	Liver
			250 μg/kg	Kidney
F22X2Tulathromycin	(2R,3S,4R,5R,8R,10R,11R,12S, 13S,14R)-2-ethyl-3,4,10,13-tetrahydroxy-3,5,8,10,12,14-hexamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-ß-D-xylo-hexopy-ranosyl]oxy]-1-oxa-6-azacyclopent-decan-15-one expressed as tulathromycin equivalents	Bovine20	100 μg/kg	Fat
			3 000 μg/kg	Liver
			3 000 μg/kg	Kidney
		Porcine	100 μg/kg	Skin + fat
			3 000 μg/kg	Liver
			3 000 μg/kg	Kidney
Tylosin	Tylosin A	All food producing species	100 μg/kg	Fat 19
			100 μg/kg	Muscle 17
			100 μg/kg	Liver
			100 μg/kg	Kidney
			50 μg/kg	Milk
			200 μg/kg	Eggs
For fin fish this MRL relates to a ‘muscle and skin in natural proportions’.
For procine species this MRL relates to ‘skin and fat in natural proportions’.
For porcine and poultry species this MRL relates to ‘skin and fat in natural proportions’.
Not for use in animals from which milk is produced for human consumption.
Not for use in animals from which milk is produced for human consumption.

F261.2.5.Florfenicol and related compounds

Pharmacologically active Substance(s)	Marker residue	Animal species	MRLs	Target tissues
Thiamphenicol	Thiamphenicol	All food producing species22	50 μg/kg	Muscle23
			50 μg/kg	Fat24
			50 μg/kg	Liver
			50 μg/kg	Kidney
			50 μg/kg	Milk
Not for use in animals from which eggs are produced for human consumption, MRLs for fat, liver and kidney do not apply to fin fish.
For fin fish muscle relates to ‘muscle and skin in natural proportions’.
For porcine and poultry species this MRL relates to ‘skin and fat in natural proportions’.

1.2.6.Tetracyclines

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues
Chlortetracycline	Sum of parent drug and its 4- epimer	All food-producing species	100 μg/kg	Muscle
			300 μg/kg	Liver
			600 μg/kg	Kidney
			100 μg/kg	Milk
			200 μg/kg	Eggs
Doxycycline	Doxycycline	Bovine	100 μg/kg	Muscle
		Not for use in animals from which milk is produced for human consumption	300 μg/kg	Liver
			600 μg/kg	Kidney
		Porcine	100 μg/kg	Muscle
			300 μg/kg	Skin and fat
			300 μg/kg	Liver
			600 μg/kg	Kidney
		Poultry	100 μg/kg	Muscle
		Not for use in animals from which eggs are produced for human consumption	300 μg/kg	Skin and fat
			300 μg/kg	Liver
			600 μg/kg	Kidney
Oxytetracycline	Sum of parent drug and its 4-epimer	All food-producing species	100 μg/kg	Muscle
			300 μg/kg	Liver
			600 μg/kg	Kidney
			100 μg/kg	Milk
			200 μg/kg	Eggs
Tetracycline	Sum of parent drug and its 4-epimer	All food-producing species	100 μg/kg	Muscle
			300 μg/kg	Liver
			600 μg/kg	Kidney
			100 μg/kg	Milk
			200 μg/kg	Eggs

1.2.7.Naphtalene-ringed ansamycin

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues	Other provisions
Rifaximin	Rifaximin	Bovine	60 μg/kg	Milk

1.2.8.Pleuromutilines

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues
F12Tiamulin	Sum of metabolites that may be hydrolysed to 8-a-hydroxymutilin	Porcine	100 μg/kg	Muscle
		Porcine	500 μg/kg	Liver
		Chicken	100 μg/kg	Muscle
			100 μg/kg	Skin and fat
			1 000 μg/kg	Liver
		F20Rabbits	100 μg/kg	Muscle
		F20Rabbits	500 μg/kg	Liver
		F15Turkey	100 μg/kg	Muscle
			100 μg/kg	Skin and fat
			300 μg/kg	Liver
	Tiamulin		1 000 μg/kg	Eggs
Valnemulin	Valnemulin	Porcine	50 μg/kg	Muscle
			500 μg/kg	Liver
			100 μg/kg	Kidney

F271.2.9.Lincosamides

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues
F3Lincomycin	Lincomicyn	All food producing species	50 μg/kg	Fat 25
			100 μg/kg	Muscle 26
			500 μg/kg	Liver
			1 500 μg/kg	Kidney
			150 μg/kg	Milk
			50 μg/kg	Eggs
F20Pirlimycin	Pirlimycin	Bovine	100 μg/kg	Muscle
			100 μg/kg	Fat
			1 000 μg/kg	Liver
			400 μg/kg	Kidney
			100 μg/kg	Milk
		Porcine	100 μg/kg	Muscle
			50 μg/kg	Skin and fat
			500 μg/kg	Liver
			1 500 μg/kg	Kidney
		Chicken	100 μg/kg	Muscle
			50 μg/kg	Skin and fat
			500 μg/kg	Liver
			1 500 μg/kg	Kidney
			50 μg/kg	Eggs
For porcine and poultry species this MRL relates to ‘skin and fat in natural proportions’.
For fin fish this MRL relates to ‘muscle and skin in natural proportions’.

F161.2.10.Aminoglycosides

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues	Other provisions
Apramycin	Apramycin	Bovine	1 000 μg/kg	Muscle	Not for use in animals from which milk is produced for human consumption
			1 000 μg/kg	Fat
			10 000 μg/kg	Liver
			20 000 μg/kg	Kidney
F29Dihydrostreptomycin	Dihydrostreptomycin	Bovine, ovine	500 μg/kg	Muscle
			500 μg/kg	Fat
			500 μg/kg	Liver
			1 000 μg/kg	Kidney
			200 μg/kg	Milk
		Porcine	500 μg/kg	Muscle
			500 μg/kg	Skin and fat
			500 μg/kg	Liver
			1 000 μg/kg	Kidney
		F30All ruminants	500 μg/kg	Muscle
			500 μg/kg	Fat
			500 μg/kg	Liver
			1 000 μg/kg	Kidney
			200 μg/kg	Milk
F31Gentamicin	Sum of gentamicin C1, gentamicin C1a, gentamicin C2 and gentamicin C2a	Bovine	50 μg/kg	Muscle
			50 μg/kg	Fat
			200 μg/kg	Liver
			750 μg/kg	Kidney
			100 μg/kg	Milk
		Porcine	50 μg/kg	Muscle
			50 μg/kg	Skin and fat
			200 μg/kg	Liver
			750 μg/kg	Kidney
F28Kanamycin	Kanamycin A	All food producing species except fish29	100 μg/kg	Muscle
			100 μg/kg	Fat27
			600 μg/kg	Liver
			2 500 μg/kg	Kidney
			150 μg/kg	Milk
F2Neomycin (including framycetin)	Neomycin B	All food producing species	500 μg/kg	Fat 27
			500 μg/kg	Muscle 28
			500 μg/kg	Liver
			5 000 μg/kg	Kidney
			1 500 μg/kg	Milk
			500 μg/kg	Eggs
F3Paromomycin	Paromomycin	All food producing species	500 μg/kg	Muscle28	Not for use in animals from which milk or eggs are produced for human consumption
			1 500 μg/kg	Liver
			1 500 μg/kg	Kidney
Spectinomycin	Spectinomycin	All food producing species except ovine	500 μg/kg	Fat27	Not for use in animals from which eggs are produced for human consumption
			300 μg/kg	Muscle 28
			1 000 μg/kg	Liver
			5 000 μg/kg	Kidney
			200 μg/kg	Milk
		Ovine	300 μg/kg	Muscle
			500 μg/kg	Fat
			2 000 μg/kg	Liver
			5 000 μg/kg	Kidney
			200 μg/kg	Milk
F29Streptomycin	Streptomycin	Bovine, ovine	500 μg/kg	Muscle
			500 μg/kg	Fat
			500 μg/kg	Liver
			1 000 μg/kg	Kidney
			200 μg/kg	Milk
		Porcine	500 μg/kg	Muscle
			500 μg/kg	Skin and fat
			500 μg/kg	Liver
			1 000 μg/kg	Kidney
For porcine and poultry species this MRL relates to ‘skin and fat in natural proportions’.
For fin fish this MRL relates to ‘muscle and skin in natural proportions’.
Not for use in animals from which eggs are produced for human consumption.

F251.2.11.Other antibiotics

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues	Other provisions
Novobiocin	Novobiocin	Bovine	50 μg/kg	Milk

F321.2.12.Polypeptides

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues
Bacitracin	Sum of bacitracin A, bacitracin B, and bacitracin C	Bovine	100 μg/kg	Milk
F33		Rabbits	150 μg/kg	Muscle
			150 μg/kg	Fat
			150 μg/kg	Liver
			150 μg/kg	Kidney

F141.2.13.Beta-lactamase inhibitors

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues
Clavulanic acid	Clavulanic acid	Bovine	100 μg/kg	Muscle
			100 μg/kg	Fat
			200 μg/kg	Liver
			400 μg/kg	Kidney
			200 μg/kg	Milk
		Porcine	100 μg/kg	Muscle
			100 μg/kg	Skin and fat
			200 μg/kg	Liver
			400 μg/kg	Kidney

F21.2.14.Polymyxins

Pharmacologically active substance	Marker residue	Animal species	MRLs	Target tissues
Colistin	Colistin	All food producing species	150 μg/kg	Fat 30
			150 μg/kg	Muscle 31
			150 μg/kg	Liver
			200 μg/kg	Kidney
			50 μg/kg	Milk
			300 μg/kg	Eggs
For porcine and poultry species this MRL relates to ‘skin and fat in natural proportions’.
For fin fish this MRL relates to ‘muscle and skin in natural proportions’.

2.Antiparasitic agents

2.1.Agents acting against endoparasites

2.1.1.Salicylanilides

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues	Other provisions
Closantel	Closantel	Bovine	1 000 μg/kg	Muscle
			3 000 μg/kg	Fat
			1 000 μg/kg	Liver
			3 000 μg/kg	Kidney
		Ovine	1 500 μg/kg	Muscle
			2 000 μg/kg	Fat
			1 500 μg/kg	Liver
			5 000 μg/kg	Kidney
F32Rafoxanide	Rafoxanide	Bovine	30 μg/kg	Muscle	Not for use in animals from which milk is produced for human consumption
			30 μg/kg	Fat
			10 μg/kg	Liver
			40 μg/kg	Kidney
		Ovine	100 μg/kg	Muscle
			250 μg/kg	Fat
			150 μg/kg	Liver
			150 μg/kg	Kidney

2.1.2.Tatra-hydro-imidazoles (imidazolthiazoles)

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues
Levamisole	Levamisole	Bovine, ovine, porcine, poultry	10 μg/kg	Muscle
			10 μg/kg	Fat
			100 μg/kg	Liver
			10 μg/kg	Kidney

2.1.3.Benzimidazoles and pro-benzimidazoles

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues	Other provisions
F35Albendazole	Sum of albendazole sulphoxide, albendazole sulphone, and albendazole 2-amino sulphone, expressed as albendazole	All ruminants	100 μg/kg	Muscle
			100 μg/kg	Fat
			1 000 μg/kg	Liver
			500 μg/kg	Kidney
			100 μg/kg	Milk
F36Albendazole oxide	Sum of albendazole oxide, albendazole sulphone and albendazole 2-aminosulphone, expressed as albendazole	Bovine, ovine	100 μg/kg	Muscle
			100 μg/kg	Fat
			1 000 μg/kg	Liver
			500 μg/kg	Kidney
			100 μg/kg	Milk
F35Febantel	Sum of extractable residues which may be oxidised to oxfendazole sulphone	All ruminants	50 μg/kg	Muscle
			50 μg/kg	Fat
			500 μg/kg	Liver
			50 μg/kg	Kidney
			10 μg/kg	Milk
Fenbendazole	Sum of extractable residues which may be oxidised to oxfendazole sulphone	All ruminants	50 μg/kg	Muscle
			50 μg/kg	Fat
			500 μg/kg	Liver
			50 μg/kg	Kidney
			10 μg/kg	Milk
F37Flubendazole	Sum of flubendazole and (2-amino 1H-benzimidazol-5-yl) (4fluorophenyl) methanone	Poultry, porcine	50 μg/kg	Muscle
			50 μg/kg	Skin + fat
			400 μg/kg	Liver
			300 μg/kg	Kidney
Flubendazole	Flubendazole	Poultry	400 μg/kg	Eggs
F38Mebendazole	Sum of mebendazole methyl (5-(1-hydroxy, 1-phenyl) methyl-1H-benzimidazol-2-yl) carbamate and (2-amino-1H-benzimidazol-5-yl) phenylmethanone, expressed as mebendazole equivalents	Ovine, caprine, equidae	60 μg/kg	Muscle	Not for use in animals from which milk is produced for human consumption
			60 μg/kg	Fat
			400 μg/kg	Liver
			60 μg/kg	Kidney
F15Netobimin	Sum of albendazole oxide, albendazole sulphone and albendazole 2-aminosulphone, expressed as albendazole	X3Bovine, ovine	100 μg/kg	Muscle	For oral use only
			100 μg/kg	Fat
			1 000 μg/kg	Liver
			500 μg/kg	Kidney
			100 μg/kg	Milk
F35Oxfendazole	Sum of extractable residues which may be oxidised to oxfendazole sulphone	All ruminants	50 μg/kg	Muscle
			50 μg/kg	Fat
			500 μg/kg	Liver
			50 μg/kg	Kidney
			10 μg/kg	Milk
Oxibendazole	Oxibendazole	Porcine	100 μg/kg	Muscle
			500 μg/kg	Skin and fat
			200 μg/kg	Liver
			100 μg/kg	Kidney
F35Thiabendazole	Sum of thiabendazole and 5-hydroxythiabendazole	Caprine	100 μg/kg	Muscle
			100 μg/kg	Fat
			100 μg/kg	Liver
			100 μg/kg	Kidney
			100 μg/kg	Milk
F39Triclabendazole	Sum of extractable residues that may be oxidised to ketotriclabendazole	All ruminants32	225 μg/kg	Muscle
			100 μg/kg	Fat
			250 μg/kg	Liver
			150 μg/kg	Kidney
Not for use in animals producing milk for human consumption.

F402.1.4.Phenol derivatives including salicylanides

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues
Nitroxinil	Nitroxinil	Bovine, ovine	400 μg/kg	Muscle
			200 μg/kg	Fat
			20 μg/kg	Liver
			400 μg/kg	Kidney
F35Oxyclozanide	Oxyclozanide	All ruminants	20 μg/kg	Muscle
			20 μg/kg	Fat
			500 μg/kg	Liver
			100 μg/kg	Kidney
			10 μg/kg	Milk

F412.1.5.Benzenesulphonamides

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues
Clorsulon	Clorsulon	Bovine	35 μg/kg	Muscle
			100 μg/kg	Liver
			200 μg/kg	Kidney

F312.1.6.Piperazine derivatives

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues
Piperazine	Piperazine	Porcine	400 μg/kg	Muscle
			800 μg/kg	Skind and fat
			2 000 μg/kg	Liver
			1 000 μg/kg	Kidney
		Chicken	2 000 μg/kg	Eggs

F422.1.7.Tetrahydropyrimides

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues
Morantel	Sum of residues which may be hydrolysed to N-methyl-1,3- propanediamine and expressed as morantel equivalents	Bovine, ovine	100 μg/kg	Muscle
			100 μg/kg	Fat
			800 μg/kg	Liver
			200 μg/kg	Kidney
			50 μg/kg	Milk
		F19All ruminants	100 μg/kg	Muscle
			100 μg/kg	Fat
			800 μg/kg	Liver
			200 μg/kg	Kidney
			50 μg/kg	Milk

2.2.Agents acting against ectoparasites

2.2.1.Organophosphates

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues	Other provisions
F32Coumafos	Coumafos	Bees	100 μg/kg	Honey
Diazinon	Diazinon	Bovine, ovine, caprine	20 μg/kg	Milk
		Bovine, porcine, ovine, caprine	20 μg/kg	Muscle
			700 μg/kg	Fat
			20 μg/kg	Liver
			20 μg/kg	Kidney
F15Phoxim	Phoxim	Ovine	50 μg/kg	Muscle	Not for use in animals from which milk is produced for human consumption
			400 μg/kg	Fat
			50 μg/kg	Kidney
		Porcine	20 μg/kg	Muscle
			700 μg/kg	Skin and fat
			20 μg/kg	Liver
			20 μg/kg	Kidney
		F5Chicken	25 μg/kg	Muscle
			550 μg/kg	Skin + fat
			50 μg/kg	Liver
			30 μg/kg	Kidney
			60 μg/kg	Eggs

2.2.2.Formamidines

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues
Amitraz	Sum of amitraz and all metabolites containing the 2,4-DMA moiety, expressed as amitraz	Bovine	200 μg/kg	Fat
			200 μg/kg	Liver
			200 μg/kg	Kidney
			10 μg/kg	Milk
		Ovine	400 μg/kg	Fat
			100 μg/kg	Liver
			200 μg/kg	Kidney
			10 μg/kg	Milk
		Porcine	400 μg/kg	Skin and fat
			200 μg/kg	Liver
			200 μg/kg	Kidney
F36		Bees (honey)	200 μg/kg	Honey
F43		Caprine	200 μg/kg	Fat
			100 μg/kg	Liver
			200 μg/kg	Kidney
			10 μg/kg	Milk

2.2.3.Pyrethroids

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues	Other provisions
F15X3Cyhalothrin	Cyhalothrin (sum of isomers)	Bovine	500 μg/kg	Fat	Further provisions in Council Directive 94/29/EC are to be observed
			50 μg/kg	Kidney
			50 μg/kg	Milk
Cyfluthrin	Cyfluthrin (sum of isomers)	Bovine	10 μg/kg	Muscle
			50 μg/kg	Fat
			10 μg/kg	Liver
			10 μg/kg	Kidney
			20 μg/kg	Milk
F44F35Deltamethrin	Deltamethrin	All ruminants	10 μg/kg	Muscle
			50 μg/kg	Fat
			10 μg/kg	Liver
			10 μg/kg	Kidney
			20 μg/kg	Milk
		F11Fin fish	10 μg/kg	Muscle and skin in natural proportions
F45Fenvalerate	Fenvalerate (sum of RR, SS, RS and SR isomers)	Bovine	25 μg/kg	Muscle
			250 μg/kg	Fat
			25 μg/kg	Liver
			25 μg/kg	Kidney
			40 μg/kg	Milk
Flumethrin	Flumethrin (sum of trans-Z isomers)	Bovine	10 μg/kg	Muscle
			150 μg/kg	Fat
			20 μg/kg	Liver
			10 μg/kg	Kidney
			30 μg/kg	Milk
F46		Ovine	10 μg/kg	Muscle	Not for use in animals from which milk is produced for human consumption
			150 μg/kg	Fat
			20 μg/kg	Liver
			10 μg/kg	Kidney
F13Permethrin	Permethrin (sum of isomers)	Bovine	50 μg/kg	Muscle
			500 μg/kg	Fat
			50 μg/kg	Liver
			50 μg/kg	Kidney
			50 μg/kg	Milk33
F47Cypermethrin	Cypermethrin (sum of isomers)	Salmonidae	50 μg/kg	Muscle and skin in natural proportions
		F35All ruminants	20 μg/kg	Muscle
			200 μg/kg	Fat
			20 μg/kg	Liver
			20 μg/kg	Kidney
			20 μg/kg	Milk33
F48Alphacypermethrin	Cypermethrin (sum of isomers)	Bovine, ovine	20 μg/kg	Muscle
			200 μg/kg	Fat
			20 μg/kg	Liver
			20 μg/kg	Kidney
			20 μg/kg	Milk33
Further provisions in Commission Directive 98/82/EC are to be observed (OJ L 290, 29.10.1998, p. 25).

F162.2.4.Acyl urea derivatives

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues
F25Diflubenzuron	Diflubenzuron	Salmonidae	1 000 μg/kg	Muscle and skin in natural proportions
F49Fluazuron	Fluazuron	Bovine34	200 μg/kg	Muscle
			7 000 μg/kg	Fat
			500 μg/kg	Liver
			500 μg/kg	Kidney
Teflubenzuron	Teflubenzuron	Salmonidae	500 μg/kg	Muscle and skin in natural proportions
Not for use in animals from which milk is produced for human consumption.

F502.2.5.Pyrimidines derivatives

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues	Other provisions
Dicyclanil	Sum of dicyclanil and 2, 4, 6-triamino-pyrimidine-5-carbonitrile	Ovine	200 μg/kg	Muscle	Not for use in animals from which milk is produced for human consumption
			F51150 μg/kg	Fat
			400 μg/kg	Liver
			400 μg/kg	Kidney

F322.2.6.Triazine derivatives

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues	Other provisions
Cyromazine	Cyromazine	Ovine	300 μg/kg	Muscle	Not for use in animals from which milk is produced for human consumption
			300 μg/kg	Fat
			300 μg/kg	Liver
			300 μg/kg	Kidney

2.3.Agents acting against endo- and ectoparasites

2.3.1.Avermectins

Phramacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues	Other provisions
Abamectin	Avermectin B1a	Bovine	10 μg/kg	Fat
			20 μg/kg	Liver
F31		Ovine	20 μg/kg	Muscle	Not for use in animals from which milk is produced for human consumption
			50 μg/kg	Fat
			25 μg/kg	Liver
			20 μg/kg	Kidney
F53Doramectin	Doramectin	All mammalian food producing species35	40 μg/kg	Muscle
			150 μg/kg	Fat
			100 μg/kg	Liver
			60 μg/kg	Kidney
F54Emamectin	Emamectin B1a	Fin fish	100 μg/kg	Muscle and skin in natural proportions
Eprinomectin	Eprinomectin B1a	Bovine	F5550 μg/kg	Muscle
			F55250 μg/kg	Fat
			F551 500 μg/kg	Liver
			F55300 μg/kg	Kidney
			F5520 μg/kg	Milk
Ivermectin	22, 23-Dihydro-avermectin B1a	Bovine	40 μg/kg	Fat
			100 μg/kg	Liver
		Porcine, ovine, equidae	20 μg/kg	Fat
			15 μg/kg	Liver
		Deer, including reindeer	20 μg/kg	Muscle
			100 μg/kg	Fat
			50 μg/kg	Liver
			20 μg/kg	Kidney
F56		All mammalian food-producing species35	100 μg/kg	Fat
			100 μg/kg	Liver
			30 μg/kg	Kidney
Moxidectin	Moxidectin	Bovine, ovine	50 μg/kg	Muscle
			500 μg/kg	Fat
			100 μg/kg	Liver
			50 μg/kg	Kidney
F14		Bovine	40 μg/kg	Milk
F41		Equidae	50 μg/kg	Muscle
			500 μg/kg	Fat
			100 μg/kg	Liver
			50 μg/kg	Kidney
F57		Ovine	40 μg/kg	Milk
Not for use in animals from which milk is produced for human consumption.

2.4.Agents acting against protozoa

2.4.1.Triazinetrione derivative

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues	Other provisions
Toltrazuril	Toltrazuril sulfone	Chicken	100 μg/kg	Muscle	Not for use in animals from which eggs are produced for human consumption
			200 μg/kg	Skin and fat
			600 μg/kg	Liver
			400 μg/kg	Kidney
		Turkey	100 μg/kg	Muscle
			200 μg/kg	Skin and fat
			600 μg/kg	Liver
			400 μg/kg	Kidney
F59		Porcine	100 μg/kg	Muscle
			150 μg/kg	Skin and fat
			500 μg/kg	Liver
			250 μg/kg	Kidney
F58		All mammalian food producing species36	100 μg/kg	Muscle
			150 μg/kg	Fat37
			500 μg/kg	Liver
			250 μg/kg	Kidney
		Poultry38	100 μg/kg	Muscle
			200 μg/kg	Skin + fat
			600 μg/kg	Liver
			400 μg/kg	Kidney
Not for use in animals from which milk is produced for human consumption.
For porcine species this MRL relates to ‘skin and fat in natural proportions’.
Not for use in animals from which eggs are produced for human consumption.

F592.4.2.Quinazolone derivatives

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues	Other provisions
Halofuginone	Halofuginone	Bovine	10 μg/kg	Muscle	Not for use in animals from which milk is produced for human consumption
			25 μg/kg	Fat
			30 μg/kg	Liver
			30 μg/kg	Kidney

F112.4.3.Carbanilides

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues
Imidocarb	Imidocarb	Bovine	300 μg/kg	Muscle
			50 μg/kg	Fat
			2 000 μg/kg	Liver
			1 500 μg/kg	Kidney
			50 μg/kg	Milk
		F17Ovine39	300 μg/kg	Muscle
			50 μg/kg	Fat
			2 000 μg/kg	Liver
			1 500 μg/kg	Kidney
Not for use in ovine from which milk is produced for human consumption.

F602.4.4.Ionophores

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues
F37Lasalocid	Lasalocid A	Poultry	20 μg/kg	Muscle
			100 μg/kg	Skin + fat
			100 μg/kg	Liver
			50 μg/kg	Kidney

3.Agents acting on the nervous system

3.1.Agents acting on the central nervous system

3.1.1.Butyrophenone tranquillisers

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues
Azaperone	Sum of azaperone and azaperol	Porcine	100 μg/kg	Muscle
			100 μg/kg	Skin and fat
			100 μg/kg	Liver
			100 μg/kg	Kidney

3.2.Agents acting on the autonomic nervous system

3.2.1.Anti-adrenergics

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues
Carazolol	Carazolol	Porcine	5 μg/kg	Muscle
			5 μg/kg	Skin and fat
			25 μg/kg	Liver
			25 μg/kg	Kidney
F7		Bovine	5 μg/kg	Muscle
			5 μg/kg	Fat
			15 μg/kg	Liver
			15 μg/kg	Kidney
			1 μg/kg	Milk

F463.2.2.β2 sympathomimetic agents

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues
Clenbuterol hydrochloride	Clenbuterol	Bovine	0,1 μg/kg	Muscle
			0,5 μg/kg	Liver
			0,5 μg/kg	Kidney
			0,05 μg/kg	Milk
		Equidae	0,1 μg/kg	Muscle
			0,5 μg/kg	Liver
			0,5 μg/kg	Kidney

4.Anti-inflammatory agents

4.1.Nonsteroidal anti-inflammatory agents

4.1.1.Arylpropionic acid derivative

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues
F16Carprofen	Carprofen	Bovine Not for use in animals from which milk is produced for human consumption	500 μg/kg	Muscle
			1 000 μg/kg	Fat
			1 000 μg/kg	Liver
			1 000 μg/kg	Kidney
		Equidae	500 μg/kg	Muscle
			1 000 μg/kg	Fat
			1 000 μg/kg	Liver
			1 000 μg/kg	Kidney
Vedaprofen	Vedaprofen	Equidae	50 μg/kg	Muscle
			20 μg/kg	Fat
			100 μg/kg	Liver
			1 000 μg/kg	Kidney
F52Carprofen	Sum of carprofen and carprofen glucuronide conjugate	Bovine, equidae	500 μg/kg	Muscle
			1 000 μg/kg	Fat
			1 000 μg/kg	Liver
			1 000 μg/kg	Kidney

4.1.2.Fenamate group derivatives

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues
F12Flunixin	Flunixin	Bovine	20 μg/kg	Muscle
			30 μg/kg	Fat
			300 μg/kg	Liver
			100 μg/kg	Kidney
	5-Hydroxyflunixin		40 μg/kg	Milk
	Flunixin	Porcine	50 μg/kg	Muscle
			10 μg/kg	Skin and fat
			200 μg/kg	Liver
			30 μg/kg	Kidney
		F59Equidae	10 μg/kg	Muscle
			20 μg/kg	Fat
			100 μg/kg	Liver
			200 μg/kg	Kidney
Tolfenamic acid	Tolfenamic acid	Bovine	50 μg/kg	Muscle
			400 μg/kg	Liver
			100 μg/kg	Kidney
			50 μg/kg	Milk
		Porcine	50 μg/kg	Muscle
			400 μg/kg	Liver
			100 μg/kg	Kidney

F294.1.3.Enolic acid derivates

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues
Meloxicam	Meloxicam	Equidae	20 μg/kg	Muscle
			65 μg/kg	Liver
			65 μg/kg	Kidney

F364.1.4.Oxican derivatives

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues
F26Meloxicam	Meloxicam	Porcine, equidae, rabbit	20 μg/kg	Muscle
			65 μg/kg	Liver
			65 μg/kg	Kidney
		Bovine, caprine	20 μg/kg	Muscle
			65 μg/kg	Liver
			65 μg/kg	Kidney
			15 μg/kg	Milk

F484.1.5.Pyrazolone derivatives

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues
Metamizole	4-Methylaminoantipyrin	Bovine	100 μg/kg	Muscle
			100 μg/kg	Fat
			100 μg/kg	Liver
			100 μg/kg	Kidney
			50 μg/kg	Milk
		Porcine	100 μg/kg	Muscle
			100 μg/kg	Skin and fat
			100 μg/kg	Liver
			100 μg/kg	Kidney
		Equidae	100 μg/kg	Muscle
			100 μg/kg	Fat
			100 μg/kg	Liver
			100 μg/kg	Kidney

F284.1.6.Phenyl acetic acid derivatives

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues
Diclofenac	Diclofenac	Bovine40	5 μg/kg	Muscle
			1 μg/kg	Fat
			5 μg/kg	Liver
			10 μg/kg	Kidney
		Porcine	5 μg/kg	Muscle
			1 μg/kg	Skin + fat
			5 μg/kg	Liver
			10 μg/kg	Kidney
Not for use in animals from which milk is produced for human consumption.

5.Corticoides

5.1.Glucocorticoides

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues	Other provisions
F25Betamethasone	Betamethasone	Bovine	0,75 μg/kg	Muscle
			2,0 μg/kg	Liver
			0,75 μg/kg	Kidney
			0,3 μg/kg	Milk
		Porcine	0,75 μg/kg	Muscle
			2,0 μg/kg	Liver
			0,75 μg/kg	Kidney
Dexamethasone	Dexamethasone	Bovine	0,3 μg/kg	Milk
		Bovine, porcine, equidae	0,75 μg/kg	Muscle
			2 μg/kg	Liver
			0,75 μg/kg	Kidney
F43		Caprine	0,75 μg/kg	Muscle
			2 μg/kg	Liver
			0,75 μg/kg	Kidney
			0,3 μg/kg	Milk
F24Methylprednisolone	Methylprednisolone	Bovine	10 μg/kg	Muscle	Not for use in animals from which milk is produced for human consumption
			10 μg/kg	Fat
			10 μg/kg	Liver
			10 μg/kg	Kidney
F61Prednisolone	Prednisolone	Bovine	4 μg/kg	Muscle
			4 μg/kg	Fat
			10 μg/kg	Liver
			10 μg/kg	Kidney
			6 μg/kg	Milk

F626.Agents acting on the reproductive system

6.1.Progestogens

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues	Other provisions
Chlormadinone	Chlormadinone	Bovine	4 μg/kg	Fat	For zootechnical use only
			2 μg/kg	Liver
			2,5 μg/kg	Milk
Flugestone acetate	Flugetone acetate	Ovine	1 μg/kg	Milk	For intravaginal use for zootechnical purposes only
		F21Caprine	1 μg/kg	Milk	For intra-vaginal use for zootechnical purposes only
		F64Ovine, caprine	0,5 μg/kg	Muscle	For therapeutic and zootechnical purposes only
			0,5 μg/kg	Fat
			0,5 μg/kg	Liver
			0,5 μg/kg	Kidney
F63Altrenogest41	Altrenogest	Porcine	1 μg/kg	Skin and fat
		Porcine	0,4 μg/kg	Liver
		Equidae	1 μg/kg	Fat
		Equidae	0,9 μg/kg	Liver
F5Norgestomet42	Norgestomet	Bovine	0,2 μg/kg	Muscle
			0,2 μg/kg	Fat
			0,2 μg/kg	Liver
			0,2 μg/kg	Kidney
			0,12 μg/kg	Milk
Only for zootechnical use and in accordance with the provisions of Directive 96/22/EC.
For therapeutic and zootechnical purposes only.