http://www.legislation.gov.uk/id/eur/1990/2377/annex/I

F1ANNEX ILIST OF PHARMACOLOGICALLY ACTIVE SUBSTANCES FOR WHICH MAXIMUM RESIDUE LIMITS HAVE BEEN FIXED

Annotations:

Amendments (Textual)

Substituted by Commission Regulation (EC) No 508/1999 of 4 March 1999 amending Annexes I to IV to Council Regulation (EEC) No 2377/90 laying down a Community procedure for the establishment of maximum residue limits of veterinary medicinal products in foodstuffs of animal origin.

2.Antiparasitic agents

2.1.Agents acting against endoparasites

2.1.1.Salicylanilides

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues	Other provisions
Closantel	Closantel	Bovine	1 000 μg/kg	Muscle
			3 000 μg/kg	Fat
			1 000 μg/kg	Liver
			3 000 μg/kg	Kidney
		Ovine	1 500 μg/kg	Muscle
			2 000 μg/kg	Fat
			1 500 μg/kg	Liver
			5 000 μg/kg	Kidney
F12Rafoxanide	Rafoxanide	Bovine	30 μg/kg	Muscle	Not for use in animals from which milk is produced for human consumption
			30 μg/kg	Fat
			10 μg/kg	Liver
			40 μg/kg	Kidney
		Ovine	100 μg/kg	Muscle
			250 μg/kg	Fat
			150 μg/kg	Liver
			150 μg/kg	Kidney

2.1.2.Tatra-hydro-imidazoles (imidazolthiazoles)

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues
Levamisole	Levamisole	Bovine, ovine, porcine, poultry	10 μg/kg	Muscle
			10 μg/kg	Fat
			100 μg/kg	Liver
			10 μg/kg	Kidney

2.1.3.Benzimidazoles and pro-benzimidazoles

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues	Other provisions
F14Albendazole	Sum of albendazole sulphoxide, albendazole sulphone, and albendazole 2-amino sulphone, expressed as albendazole	All ruminants	100 μg/kg	Muscle
			100 μg/kg	Fat
			1 000 μg/kg	Liver
			500 μg/kg	Kidney
			100 μg/kg	Milk
F15Albendazole oxide	Sum of albendazole oxide, albendazole sulphone and albendazole 2-aminosulphone, expressed as albendazole	Bovine, ovine	100 μg/kg	Muscle
			100 μg/kg	Fat
			1 000 μg/kg	Liver
			500 μg/kg	Kidney
			100 μg/kg	Milk
F14Febantel	Sum of extractable residues which may be oxidised to oxfendazole sulphone	All ruminants	50 μg/kg	Muscle
			50 μg/kg	Fat
			500 μg/kg	Liver
			50 μg/kg	Kidney
			10 μg/kg	Milk
Fenbendazole	Sum of extractable residues which may be oxidised to oxfendazole sulphone	All ruminants	50 μg/kg	Muscle
			50 μg/kg	Fat
			500 μg/kg	Liver
			50 μg/kg	Kidney
			10 μg/kg	Milk
F16Flubendazole	Sum of flubendazole and (2-amino 1H-benzimidazol-5-yl) (4fluorophenyl) methanone	Poultry, porcine	50 μg/kg	Muscle
			50 μg/kg	Skin + fat
			400 μg/kg	Liver
			300 μg/kg	Kidney
Flubendazole	Flubendazole	Poultry	400 μg/kg	Eggs
F17Mebendazole	Sum of mebendazole methyl (5-(1-hydroxy, 1-phenyl) methyl-1H-benzimidazol-2-yl) carbamate and (2-amino-1H-benzimidazol-5-yl) phenylmethanone, expressed as mebendazole equivalents	Ovine, caprine, equidae	60 μg/kg	Muscle	Not for use in animals from which milk is produced for human consumption
			60 μg/kg	Fat
			400 μg/kg	Liver
			60 μg/kg	Kidney
F6Netobimin	Sum of albendazole oxide, albendazole sulphone and albendazole 2-aminosulphone, expressed as albendazole	X1Bovine, ovine	100 μg/kg	Muscle	For oral use only
			100 μg/kg	Fat
			1 000 μg/kg	Liver
			500 μg/kg	Kidney
			100 μg/kg	Milk
F14Oxfendazole	Sum of extractable residues which may be oxidised to oxfendazole sulphone	All ruminants	50 μg/kg	Muscle
			50 μg/kg	Fat
			500 μg/kg	Liver
			50 μg/kg	Kidney
			10 μg/kg	Milk
Oxibendazole	Oxibendazole	Porcine	100 μg/kg	Muscle
			500 μg/kg	Skin and fat
			200 μg/kg	Liver
			100 μg/kg	Kidney
F14Thiabendazole	Sum of thiabendazole and 5-hydroxythiabendazole	Caprine	100 μg/kg	Muscle
			100 μg/kg	Fat
			100 μg/kg	Liver
			100 μg/kg	Kidney
			100 μg/kg	Milk
F18Triclabendazole	Sum of extractable residues that may be oxidised to ketotriclabendazole	All ruminants32	225 μg/kg	Muscle
			100 μg/kg	Fat
			250 μg/kg	Liver
			150 μg/kg	Kidney
Not for use in animals producing milk for human consumption.

F192.1.4.Phenol derivatives including salicylanides

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues
Nitroxinil	Nitroxinil	Bovine, ovine	400 μg/kg	Muscle
			200 μg/kg	Fat
			20 μg/kg	Liver
			400 μg/kg	Kidney
F14Oxyclozanide	Oxyclozanide	All ruminants	20 μg/kg	Muscle
			20 μg/kg	Fat
			500 μg/kg	Liver
			100 μg/kg	Kidney
			10 μg/kg	Milk

F202.1.5.Benzenesulphonamides

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues
Clorsulon	Clorsulon	Bovine	35 μg/kg	Muscle
			100 μg/kg	Liver
			200 μg/kg	Kidney

F112.1.6.Piperazine derivatives

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues
Piperazine	Piperazine	Porcine	400 μg/kg	Muscle
			800 μg/kg	Skind and fat
			2 000 μg/kg	Liver
			1 000 μg/kg	Kidney
		Chicken	2 000 μg/kg	Eggs

F212.1.7.Tetrahydropyrimides

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues
Morantel	Sum of residues which may be hydrolysed to N-methyl-1,3- propanediamine and expressed as morantel equivalents	Bovine, ovine	100 μg/kg	Muscle
			100 μg/kg	Fat
			800 μg/kg	Liver
			200 μg/kg	Kidney
			50 μg/kg	Milk
		F9All ruminants	100 μg/kg	Muscle
			100 μg/kg	Fat
			800 μg/kg	Liver
			200 μg/kg	Kidney
			50 μg/kg	Milk

2.2.Agents acting against ectoparasites

2.2.1.Organophosphates

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues	Other provisions
F12Coumafos	Coumafos	Bees	100 μg/kg	Honey
Diazinon	Diazinon	Bovine, ovine, caprine	20 μg/kg	Milk
		Bovine, porcine, ovine, caprine	20 μg/kg	Muscle
			700 μg/kg	Fat
			20 μg/kg	Liver
			20 μg/kg	Kidney
F6Phoxim	Phoxim	Ovine	50 μg/kg	Muscle	Not for use in animals from which milk is produced for human consumption
			400 μg/kg	Fat
			50 μg/kg	Kidney
		Porcine	20 μg/kg	Muscle
			700 μg/kg	Skin and fat
			20 μg/kg	Liver
			20 μg/kg	Kidney
		F2Chicken	25 μg/kg	Muscle
			550 μg/kg	Skin + fat
			50 μg/kg	Liver
			30 μg/kg	Kidney
			60 μg/kg	Eggs

2.2.2.Formamidines

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues
Amitraz	Sum of amitraz and all metabolites containing the 2,4-DMA moiety, expressed as amitraz	Bovine	200 μg/kg	Fat
			200 μg/kg	Liver
			200 μg/kg	Kidney
			10 μg/kg	Milk
		Ovine	400 μg/kg	Fat
			100 μg/kg	Liver
			200 μg/kg	Kidney
			10 μg/kg	Milk
		Porcine	400 μg/kg	Skin and fat
			200 μg/kg	Liver
			200 μg/kg	Kidney
F15		Bees (honey)	200 μg/kg	Honey
F22		Caprine	200 μg/kg	Fat
			100 μg/kg	Liver
			200 μg/kg	Kidney
			10 μg/kg	Milk

2.2.3.Pyrethroids

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues	Other provisions
F6X1Cyhalothrin	Cyhalothrin (sum of isomers)	Bovine	500 μg/kg	Fat	Further provisions in Council Directive 94/29/EC are to be observed
			50 μg/kg	Kidney
			50 μg/kg	Milk
Cyfluthrin	Cyfluthrin (sum of isomers)	Bovine	10 μg/kg	Muscle
			50 μg/kg	Fat
			10 μg/kg	Liver
			10 μg/kg	Kidney
			20 μg/kg	Milk
F23F14Deltamethrin	Deltamethrin	All ruminants	10 μg/kg	Muscle
			50 μg/kg	Fat
			10 μg/kg	Liver
			10 μg/kg	Kidney
			20 μg/kg	Milk
		F3Fin fish	10 μg/kg	Muscle and skin in natural proportions
F24Fenvalerate	Fenvalerate (sum of RR, SS, RS and SR isomers)	Bovine	25 μg/kg	Muscle
			250 μg/kg	Fat
			25 μg/kg	Liver
			25 μg/kg	Kidney
			40 μg/kg	Milk
Flumethrin	Flumethrin (sum of trans-Z isomers)	Bovine	10 μg/kg	Muscle
			150 μg/kg	Fat
			20 μg/kg	Liver
			10 μg/kg	Kidney
			30 μg/kg	Milk
F25		Ovine	10 μg/kg	Muscle	Not for use in animals from which milk is produced for human consumption
			150 μg/kg	Fat
			20 μg/kg	Liver
			10 μg/kg	Kidney
F4Permethrin	Permethrin (sum of isomers)	Bovine	50 μg/kg	Muscle
			500 μg/kg	Fat
			50 μg/kg	Liver
			50 μg/kg	Kidney
			50 μg/kg	Milk33
F26Cypermethrin	Cypermethrin (sum of isomers)	Salmonidae	50 μg/kg	Muscle and skin in natural proportions
		F14All ruminants	20 μg/kg	Muscle
			200 μg/kg	Fat
			20 μg/kg	Liver
			20 μg/kg	Kidney
			20 μg/kg	Milk33
F27Alphacypermethrin	Cypermethrin (sum of isomers)	Bovine, ovine	20 μg/kg	Muscle
			200 μg/kg	Fat
			20 μg/kg	Liver
			20 μg/kg	Kidney
			20 μg/kg	Milk33
Further provisions in Commission Directive 98/82/EC are to be observed (OJ L 290, 29.10.1998, p. 25).

F72.2.4.Acyl urea derivatives

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues
F10Diflubenzuron	Diflubenzuron	Salmonidae	1 000 μg/kg	Muscle and skin in natural proportions
F28Fluazuron	Fluazuron	Bovine34	200 μg/kg	Muscle
			7 000 μg/kg	Fat
			500 μg/kg	Liver
			500 μg/kg	Kidney
Teflubenzuron	Teflubenzuron	Salmonidae	500 μg/kg	Muscle and skin in natural proportions
Not for use in animals from which milk is produced for human consumption.

F292.2.5.Pyrimidines derivatives

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues	Other provisions
Dicyclanil	Sum of dicyclanil and 2, 4, 6-triamino-pyrimidine-5-carbonitrile	Ovine	200 μg/kg	Muscle	Not for use in animals from which milk is produced for human consumption
			F30150 μg/kg	Fat
			400 μg/kg	Liver
			400 μg/kg	Kidney

F122.2.6.Triazine derivatives

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues	Other provisions
Cyromazine	Cyromazine	Ovine	300 μg/kg	Muscle	Not for use in animals from which milk is produced for human consumption
			300 μg/kg	Fat
			300 μg/kg	Liver
			300 μg/kg	Kidney

2.3.Agents acting against endo- and ectoparasites

2.3.1.Avermectins

Phramacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues	Other provisions
Abamectin	Avermectin B1a	Bovine	10 μg/kg	Fat
			20 μg/kg	Liver
F11		Ovine	20 μg/kg	Muscle	Not for use in animals from which milk is produced for human consumption
			50 μg/kg	Fat
			25 μg/kg	Liver
			20 μg/kg	Kidney
F32Doramectin	Doramectin	All mammalian food producing species35	40 μg/kg	Muscle
			150 μg/kg	Fat
			100 μg/kg	Liver
			60 μg/kg	Kidney
F33Emamectin	Emamectin B1a	Fin fish	100 μg/kg	Muscle and skin in natural proportions
Eprinomectin	Eprinomectin B1a	Bovine	F3450 μg/kg	Muscle
			F34250 μg/kg	Fat
			F341 500 μg/kg	Liver
			F34300 μg/kg	Kidney
			F3420 μg/kg	Milk
Ivermectin	22, 23-Dihydro-avermectin B1a	Bovine	40 μg/kg	Fat
			100 μg/kg	Liver
		Porcine, ovine, equidae	20 μg/kg	Fat
			15 μg/kg	Liver
		Deer, including reindeer	20 μg/kg	Muscle
			100 μg/kg	Fat
			50 μg/kg	Liver
			20 μg/kg	Kidney
F35		All mammalian food-producing species35	100 μg/kg	Fat
			100 μg/kg	Liver
			30 μg/kg	Kidney
Moxidectin	Moxidectin	Bovine, ovine	50 μg/kg	Muscle
			500 μg/kg	Fat
			100 μg/kg	Liver
			50 μg/kg	Kidney
F5		Bovine	40 μg/kg	Milk
F20		Equidae	50 μg/kg	Muscle
			500 μg/kg	Fat
			100 μg/kg	Liver
			50 μg/kg	Kidney
F36		Ovine	40 μg/kg	Milk
Not for use in animals from which milk is produced for human consumption.

2.4.Agents acting against protozoa

2.4.1.Triazinetrione derivative

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues	Other provisions
Toltrazuril	Toltrazuril sulfone	Chicken	100 μg/kg	Muscle	Not for use in animals from which eggs are produced for human consumption
			200 μg/kg	Skin and fat
			600 μg/kg	Liver
			400 μg/kg	Kidney
		Turkey	100 μg/kg	Muscle
			200 μg/kg	Skin and fat
			600 μg/kg	Liver
			400 μg/kg	Kidney
F38		Porcine	100 μg/kg	Muscle
			150 μg/kg	Skin and fat
			500 μg/kg	Liver
			250 μg/kg	Kidney
F37		All mammalian food producing species36	100 μg/kg	Muscle
			150 μg/kg	Fat37
			500 μg/kg	Liver
			250 μg/kg	Kidney
		Poultry38	100 μg/kg	Muscle
			200 μg/kg	Skin + fat
			600 μg/kg	Liver
			400 μg/kg	Kidney
Not for use in animals from which milk is produced for human consumption.
For porcine species this MRL relates to ‘skin and fat in natural proportions’.
Not for use in animals from which eggs are produced for human consumption.

F382.4.2.Quinazolone derivatives

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues	Other provisions
Halofuginone	Halofuginone	Bovine	10 μg/kg	Muscle	Not for use in animals from which milk is produced for human consumption
			25 μg/kg	Fat
			30 μg/kg	Liver
			30 μg/kg	Kidney

F32.4.3.Carbanilides

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues
Imidocarb	Imidocarb	Bovine	300 μg/kg	Muscle
			50 μg/kg	Fat
			2 000 μg/kg	Liver
			1 500 μg/kg	Kidney
			50 μg/kg	Milk
		F8Ovine39	300 μg/kg	Muscle
			50 μg/kg	Fat
			2 000 μg/kg	Liver
			1 500 μg/kg	Kidney
Not for use in ovine from which milk is produced for human consumption.

F392.4.4.Ionophores

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues
F16Lasalocid	Lasalocid A	Poultry	20 μg/kg	Muscle
			100 μg/kg	Skin + fat
			100 μg/kg	Liver
			50 μg/kg	Kidney