ANNEXU.K.

[F144. DETERMINATION OF ETHYL CARBAMATE IN WINE: SELECTIVE DETECTION METHOD USING GAS CHROMATOGRAPHY/MASS SPECTROMETRY U.K.

E. Extraction U.K.

Extraction should be carried out under an extractor hood, with adequate ventilation.

Transfer the sample prepared under heading D to the extraction column.

Rinse the beaker with 10 ml of water and transfer the rinsing water to the column.

Leave the liquid to absorb for four minutes. Elute with 2 × 80 ml of dichloromethane. Collect the eluate in a 300 ml conical flask.

Evaporate the eluate from 2 to 3 ml in a water bath rotary evaporator at 30 °C. (

NB: do not allow to boil dry. U.K.

)

Transfer the concentrated residue to a 4 ml graduated tube with a Pasteur pipette.

Rinse the flask with 1 ml of dichloromethane and transfer the rinsing liquid to the tube. Concentrate the sample to 1 ml under a weak nitrogen stream.

If necessary, transfer the concentrate to auto sampler flask for GC/MS analysis.]