http://www.legislation.gov.uk/id/eur/1999/508

ANNEX IIILIST OF PHARMACOLOGICALLY ACTIVE SUBSTANCES USED IN VETERINARY MEDICINAL PRODUCTS FOR WHICH PROVISIONAL MAXIMUM RESIDUE LIMITS HAVE BEEN FIXED

1.

Anti-infectious agents

1.1.

Chemotheurapeutics

1.1.2.

Benzenesulphonamides

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues	Other provisions
Clorsulon	Clorsulon	Bovine	50 μg/kg	Muscle	Provisional MRLs expire on 1 January 2000
			150 μg/kg	Liver
			400 μg/kg	Kidney

1.2.

Antibiotics

1.2.1.

Beta-lactamase inhibitors

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues	Other provisions
Clavulanic acid	Clavulanic acid	Bovine, ovine	200 μg/kg	Milk	Provisional MRLs expire on 1 July 1999
		Bovine, ovine, porcine	200 μg/kg	Muscle
			200 μg/kg	Fat
			200 μg/kg	Liver
			200 μg/kg	Kidney

1.2.2.

Macrolides

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues	Other provisions
Erythromycin	MRLs apply to all microbiological active residues expressed as erythromycin equivalent	Bovine, ovine	40 μg/kg	Milk	Provisional MRLs expire on 1 June 2000
		Bovine, ovine, porcine, poultry	400 μg/kg	Muscle
			400 μg/kg	Fat
			400 μg/kg	Liver
			400 μg/kg	Kidney
		Poultry	200 μg/kg	Eggs
Josamycin	Josamycin	Chicken	200 μg/kg	Muscle	Provisional MRLs expire on 1 July 2000
			200 μg/kg	Fat
			200 μg/kg	Liver
			400 μg/kg	Kidney
			200 μg/kg	Eggs

1.2.5.

Aminoglycosides

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues	Other provisions
Aminosidine	Aminosidine	Bovine, porcine, rabbits, chicken	500 μg/kg	Muscle	Provisional MRLs expire on 1 July 2000
			1 500 μg/kg	Liver
			1 500 μg/kg	Kidney
Apramycin	Apramycin	Bovine	1 000 μg/kg	Muscle	Provisional MRLs expire on 1 July 1999
		For use in non-lactating cattle only	1 000 μg/kg	Fat
			10 000 μg/kg	Liver
			20 000 μg/kg	Kidney
		Porcine	1 000 μg/kg	Muscle
			1 000 μg/kg	Skin and fat
			1 000 μg/kg	Liver
			5 000 μg/kg	Kidney
Dihydrostreptomycin	Dihydrostreptomycin	Bovine, ovine	200 μg/kg	Milk	Provisional MRLs expire on 1 June 2000
		Bovine, ovine, porcine, poultry	500 μg/kg	Muscle
			500 μg/kg	Fat
			500 μg/kg	Liver
			1 000 μg/kg	Kidney
Gentamicin	Gentamicin	Bovine	100 μg/kg	Milk	Provisional MRLs expire on 1 June 2000
		Bovine, porcine	100 μg/kg	Muscle
			100 μg/kg	Fat
			200 μg/kg	Liver
			1 000 μg/kg	Kidney
Neomycin (including framycetin)	Neomycin	Bovine, ovine, caprine	500 μg/kg	Milk	Provisional MRLs expire on 1 June 2000
		Bovine, ovine, caprine, porcine, chicken, turkey, duck	500 μg/kg	Muscle
			500 μg/kg	Fat
			500 μg/kg	Liver
			5 000 μg/kg	Kidney
		Chicken	500 μg/kg	Eggs
Spectinomycin	Spectinomycin	Bovine	200 μg/kg	Milk	Provisional MRLs expire on 1 July 2000
		Bovine, porcine, poultry	300 μg/kg	Muscle
			500 μg/kg	Fat
			2 000 μg/kg	Liver
			5 000 μg/kg	Kidney
Streptomycin	Streptomycin	Bovine, ovine	200 μg/kg	Milk	Provisional MRLs expire on 1 June 2000
		Bovine, ovine, porcine, poultry	500 μg/kg	Muscle
			500 μg/kg	Fat
			500 μg/kg	Liver
			1 000 μg/kg	Kidney

1.2.6.

Quinolones

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues	Other provisions
Decoquinate	Decoquinate	Bovine, ovine	500 μg/kg	Muscle	Provisional MRLs expire on 1 July 2000
			500 μg/kg	Fat
			500 μg/kg	Liver
			500 μg/kg	Kidney
Enrofloxacin	Sum of enrofloxacin and ciprofloxacin	Ovine	100 μg/kg	Muscle	Provisional MRLs expire on 1 July 1999
			100 μg/kg	Fat
			300 μg/kg	Liver
			200 μg/kg	Kidney
Flumequine	Flumequine	Bovine, ovine, porcine, chicken	50 μg/kg	Muscle	Provisional MRLs expire on 1 January 2000
			50 μg/kg	Fat or skin and fat
			100 μg/kg	Liver
			300 μg/kg	Kidney
		Salmonidae	150 μg/kg	Muscle and skin
Marbofloxacin	Marbofloxacin	Bovine	150 μg/kg	Muscle	Provisional MRLs expire on 1 July 2000
			50 μg/kg	Fat
			150 μg/kg	Liver
			150 μg/kg	Kidney
			75 μg/kg	Milk
		Porcine	150 μg/kg	Muscle
			50 μg/kg	Skin and fat
			150 μg/kg	Liver
			150 μg/kg	Kidney

1.2.9.

Polymyxins

Phamarcologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues	Other provisions
Colistin	Colistin	Bovine, ovine	50 μg/kg	Milk	Provisional MRLs expire on 1 July 2000
		Bovine, ovine, porcine, chicken, rabbits	150 μg/kg	Muscle
			150 μg/kg	Fat
			150 μg/kg	Liver
			200 μg/kg	Kidney
		Chicken	300 μg/kg	Eggs

1.2.10.

Penicillins

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues	Other provisions
Penethamate	Benzylpenicillin	Ovine	50 μg/kg	Muscle	Provisional MRLs expire on 1 January 2000
			50 μg/kg	Fat
			50 μg/kg	Liver
			50 μg/kg	Kidney
			4 μg/kg	Milk
		Porcine	50 μg/kg	Muscle
			50 μg/kg	Fat
			50 μg/kg	Liver
			50 μg/kg	Kidney

1.2.11.

Florfenicol and related compounds

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues	Other provisions
Florfenicol	Sum of florfenicol and its metabolites measured as florfenicol-amine	Fish	1 000 μg/kg	Muscle and skin in natural proportions	Provisional MRLs expire on 1 July 2001

2.

Antiparasitic agents

2.1.

Agents acting against endoparasites

2.1.2.

Benzimidazoles and pro-benzimidazoles

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues	Other provisions
Albendazole sulphoxide	Sum of albendazole, albendazole sulphoxide, albendazole sulphone, and albendazole 2-amino sulphone, expressed as albendazole	Bovine, ovine	100 μg/kg	Milk	Provisional MRLs expire on 1 January 2000
		Bovine, ovine, pheasant	100 μg/kg	Muscle
			100 μg/kg	Fat
			1 000 μg/kg	Liver
			500 μg/kg	Kidney
Netobimin	Sum of netobimin and albendazole and metabolites of albendazole measured as 2-amino- benzimidazole sulphone	Bovine, ovine, caprine	100 μg/kg	Muscle	Provisional MRLs expire on 31 July 1999
			100 μg/kg	Fat
			1 000 μg/kg	Liver
			500 μg/kg	Kidney
			100 μg/kg	Milk

2.2.

Agents acting against ectoparasites

2.2.1.

Formamidines

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues	Other provisions
Amitraz	Sum of amitraz and all metabolites containing the 2,4-DMA moeity, expressed as amitraz	Bees	200 μg/kg	Honey	Provisional MRLs expire on 1 July 1999

2.2.2.

Iminophenyl thiazolidine derivative

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues	Other provisions
Cymiazole	Cymiazole	Bees	1 000 μg/kg	Honey	Provisional MRLs expire on 1 July 1999

2.2.3.

Pyretrin and pyrethroids

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues	Other provisions
Cyfluthrin	Cyfluthrin	Bovine	10 μg/kg	Muscle	Provisional MRLs expire on 1 January 2001
			50 μg/kg	Fat
			10 μg/kg	Liver
			10 μg/kg	Kidney
			20 μg/kg	Milk
				Further provisions in Council Directive 94/29/EC are to be observed (OJ L 189, 23.7.1994, p. 67)

2.2.4.

Organophosphates

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues	Other provisions
Azamethiphos	Azamethiphos	Salmonidae	100 μg/kg	Muscle and skin in natural proportions	Provisional MRLs expire on 1 June 1999

2.2.5.

Acyl urea derivates

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues	Other provisions
Teflubenzuron	Teflubenzuron	Salmonidae	500 μg/kg	Muscle and skin in natural proportions	Provisional MRLs expire on 1 July 1999

2.3.

Agents acting against endo- and ectoparasites

2.3.1.

Avermectins

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues	Other provisions
Moxidectin	Moxidectin	Equidae	50 μg/kg	Muscle	Provisional MRLs expire on 1 January 2000
			500 μg/kg	Fat
			100 μg/kg	Liver
			50 μg/kg	Kidney

3.

Agents acting on the nervous system

3.2.

Agents acting on the autonomic nervous system

3.2.1.

β 2 sympathomimetic agents

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues	Other provisions
Clenbuterol hydrochloride	Clenbuterol	Bovine	0,1 μg/kg	Muscle	Provisional MRLs expire on 1 July 2000
		Indication: solely for tocolysis in parturient cows	0,5 μg/kg	Liver
			0,5 μg/kg	Kidney
			0,05 μg/kg	Milk
		Equidae	0,1 μg/kg	Muscle
		Indications: tocolysis and the treatment of respiratory ailments	0,5 μg/kg	Liver
			0,5 μg/kg	Kidney

5.

Anti-inflammatory agents

5.1.

Nonsteroidal anti-inflammatory agents

5.1.1.

Arylpropionic acid derivative

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues	Other provisions
Carprofen	Carprofen	Bovine	500 μg/kg	Muscle	Provisional MRLs expire on 1 January 2000
			500 μg/kg	Fat
			1 000 μg/kg	Liver
			1 000 μg/kg	Kidney
		Equidae	50 μg/kg	Muscle
			100 μg/kg	Fat
			1 000 μg/kg	Liver
			1 000 μg/kg	Kidney

5.1.2.

Enolic acid derivates

Pharmacologically active substance(s)	Marker residue	Animal species	MRLs	Target tissues	Other provisions
Meloxicam	Meloxicam	Bovine	25 μg/kg	Muscle	Provisional MRLs expire on 1 January 2000
			60 μg/kg	Liver
			35 μg/kg	Kidney