Regulation (EC) No 1272/2008 of the European Parliament and of the CouncilShow full title

1. Part 1: Criteria for the selection of precautionary statements U.K.

Table 6.1

Precautionary statements — General

Code	General precautionary statements	Hazard class	Hazard category	Conditions for use
(1)	(2)	(3)	(4)	(5)
P101	If medical advice is needed, have product container or label at hand.	as appropriate		Consumer products
P102	Keep out of reach of children.	as appropriate		Consumer products
[F1 P103	Read carefully and follow all instructions.	as appropriate		Consumer products – omit where P202 is used]

Textual Amendments

F1 Substituted by Commission Regulation (EU) 2019/521 of 27 March 2019 amending, for the purposes of its adaptation to technical and scientific progress Regulation (EC) No 1272/2008 of the European Parliament and of the Council on classification, labelling and packaging of substances and mixtures (Text with EEA relevance).

Table 6.2

Precautionary statements — Prevention

Code	Prevention precautionary statements	Hazard class	Hazard category	Conditions for use
(1)	(2)	(3)	(4)	(5)
[F1 P201	Obtain special instructions before use.	Explosives (section 2.1)	Unstable explosive
		Germ cell mutagenicity (section 3.5)	1A,1B, 2	Consumer products – omit where P202 is used
		Carcinogenicity (section 3.6)	1A,1B, 2
		Reproductive toxicity (section 3.7)	1A,1B, 2
		Reproductive toxicity — effects on or via lactation (section 3.7)	Additional category
P202	Do not handle until all safety precautions have been read and understood.	Flammable gases (section 2.2)	A, B (chemically unstable gases)
		Germ cell mutagenicity (section 3.5)	1A,1B, 2
		Carcinogenicity (section 3.6)	1A,1B, 2
		Reproductive toxicity (section 3.7)	1A,1B, 2
		Reproductive toxicity, effects on or via lactation (section 3.7)	Additional category	]
[F1 P210	Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.	Explosives (section 2.1)	Divisions 1.1, 1.2, 1.3, 1.4, 1.5
		Flammable gases (section 2.2)	1A, 1B, 2
		Aerosols (section 2.3)	1, 2, 3
		Flammable liquids (section 2.6)	1, 2, 3
		Flammable solids (section 2.7)	1, 2
		Self-reactive substances and mixtures (section 2.8)	Types A, B, C, D, E, F
		Pyrophoric liquids (section 2.9)	1
		Pyrophoric solids (section 2.10)	1
		Oxidising liquids (section 2.13)	1, 2, 3
		Oxidising solids (section 2.14)	1, 2, 3
		Organic peroxides (section 2.15)	Types A, B, C, D, E, F
		Desensitised explosives (section 2.17)	1, 2, 3, 4	]
[F2 P211	Do not spray on an open flame or other ignition source.	Aerosols (section 2.3)	1, 2	]
[F3 P212	Avoid heating under confinement or reduction of the desensitising agent.	Desensitised explosives (section 2.17)	1, 2, 3, 4	]
[F4 P220	Keep away from clothing and other combustible materials.	Oxidising gases (Section 2.4)	1
		Oxidising liquids (Section 2.13)	1, 2, 3
		Oxidising solids (Section 2.14)	1, 2, 3]
[ F5
F5 ]
[F1 P222	Do not allow contact with air.	Flammable gases (section 2.2)	Pyrophoric gas	if emphasis of the hazard statement is deemed necessary .
		Pyrophoric liquids (section 2.9)	1
		Pyrophoric solids (section 2.10)	1]
[F4 P223	Do not allow contact with water.	Substances and mixtures which, in contact with water, emit flammable gases (Section 2.12)	1, 2	— if emphasis of the hazard statement is deemed necessary
[F1 P230	Keep wetted with …	Explosives (section 2.1)	Divisions 1.1, 1.2, 1.3, 1.5	Manufacturer/supplier to specify appropriate material for substances and mixtures which are wetted, diluted, dissolved or suspended with a phlegmatiser in order to suppress their explosive properties
		Desensitised explosives (section 2.17)	1, 2, 3, 4	Manufacturer/supplier to specify appropriate material]
P231	Handle and store contents under inert gas/…	Pyrophoric liquids (Section 2.9)	1	… Manufacturer/supplier to specify appropriate liquid or gas if ‘ inert gas ’ is not appropriate.
		Pyrophoric solids (Section 2.10)	1
		Substances and mixtures which, in contact with water, emit flammable gases (Section 2.12)	1, 2, 3	— if the substance or mixture reacts readily with moisture in air. … Manufacturer/supplier to specify appropriate liquid or gas if ‘ inert gas ’ is not appropriate.]
P232	Protect from moisture.	Substances and mixtures which, in contact with water, emit flammable gases (section 2.12)	1, 2, 3
[F1 P233	Keep container tightly closed.	Flammable liquids (section 2.6)	1, 2, 3	if the liquid is volatile and may generate an explosive atmosphere
		Pyrophoric liquids (section 2.9)	1
		Pyrophoric solids (section 2.10)	1
		Desensitised explosives (section 2.17)	1, 2, 3, 4
		Acute toxicity – inhalation (section 3.1)	1, 2, 3	if the chemical is volatile and may generate a hazardous atmosphere
		Specific target organ toxicity – single exposure; respiratory tract irritation (section 3.8)	3
		Specific target organ toxicity – single exposure; narcotic effects (section 3.8)	3]
[F4 P234	Keep only in original packaging.	Explosives (Section 2.1)	Divisions 1.1, 1.2, 1.3, 1.4, 1.5
		Self-reactive substances and mixtures (Section 2.8)	Types A, B, C, D, E, F
		Organic peroxides (Section 2.15)	Types A, B, C, D, E, F
		Corrosive to metals (Section 2.16)	1
P235	Keep cool.	Flammable liquids (Section 2.6)	1, 2, 3	— for flammable liquids category 1 and other flammable liquids that are volatile and may generate an explosive atmosphere
		Self-reactive substances and mixtures (Section 2.8)	Types A, B, C, D, E, F	— may be omitted if P411 is given on the label
		Self-heating substances and mixtures (Section 2.11)	1, 2	— may be omitted if P413 is given on the label
		Organic peroxides (Section 2.15)	Types A, B, C, D, E, F	— may be omitted if P411 is given on the label
P240	Ground and bond container and receiving equipment.	Explosives (Section 2.1)	Divisions 1.1, 1.2, 1.3, 1.4, 1.5	— if the explosive is electrostatically sensitive
		Flammable liquids (Section 2.6)	1, 2, 3	— if the liquid is volatile and may generate an explosive atmosphere
		Flammable solids (Section 2.7)	1, 2	— if the solid is electrostatically sensitive
		Self-reactive substances and mixtures (Section 2.8)	Types A,B,C, D, E, F	— if electrostatically sensitive and able to generate an explosive atmosphere
		Organic peroxides (Section 2.15)
P241	Use explosion-proof [electrical/ventilating/lighting/…] equipment.	Flammable liquids (Section 2.6)	1, 2, 3	if the liquid is volatile and may generate an explosive atmosphere. text in square brackets may be used to specify specific electrical, ventilating, lighting or other equipment if necessary and as appropriate.
		Flammable solids (Section 2.7)	1, 2	if dust clouds can occur. text in square brackets may be used to specify specific electrical, ventilating, lighting or other equipment if necessary and as appropriate.
P242	Use non-sparking tools.	Flammable liquids (Section 2.6)	1, 2, 3	— if the liquid is volatile and may generate an explosive atmosphere and if the minimum ignition energy is very low. (This applies to substances and mixtures where the ignition energy is < 0,1 mJ, e.g. carbon disulphide).
P243	Take action to prevent static discharges.	Flammable liquids (Section 2.6)	1, 2, 3	— if the liquid is volatile and may generate an explosive atmosphere.]
[F2 P244	Keep valves and fittings free from oil and grease.	Oxidising gases (section 2.4)	1	]
[F4 P250	Do not subject to grinding/shock/friction …	Explosives (Section 2.1)	Unstable explosives and divisions 1.1, 1.2, 1.3, 1.4, 1.5	— if the explosive is mechanically sensitive … Manufacturer/supplier to specify applicable rough handling.]
[F2 P251	Do not pierce or burn, even after use.	Aerosols (section 2.3)	1, 2, 3	]
P260	Do not breathe dust/fume/gas/mist/vapours/spray.	Acute toxicity — inhalation (section 3.1)	1, 2	Manufacturer/supplier to specify applicable conditions.
		Specific target organ toxicity — single exposure (section 3.8)	1, 2
		Specific target organ toxicity — repeated exposure (section 3.9)	1, 2
		Skin corrosion (section 3.2)	1A, 1B, 1C	Specify do not breathe dusts or mists. if inhalable particles of dusts or mists may occur during use.
		Reproductive toxicity — effects on or via lactation (section 3.7)	Additional category
[F4 P261	Avoid breathing dust/fume/gas/mist/vapours/spray.	Acute toxicity — inhalation (Section 3.1)	3, 4	— may be omitted if P260 is given on the label Manufacturer/supplier to specify applicable conditions.
		Respiratory sensitisation (Section 3.4)	1, 1A, 1B
		Skin sensitisation (Section 3.4)	1, 1A, 1B
		Specific target organ toxicity — single exposure; respiratory tract irritation (Section 3.8)	3
		Specific target organ toxicity — single exposure; narcotic effects (Section 3.8)	3]
P262	Do not get in eyes, on skin, or on clothing.	Acute toxicity — dermal (section 3.1)	1, 2
[F4 P263	Avoid contact during pregnancy and while nursing.	Reproductive toxicity — effects on or via lactation (Section 3.7)	Additional category	]
P264	Wash … thoroughly after handling.	Acute toxicity — oral (section 3.1)	1, 2, 3, 4	Manufacturer/supplier to specify parts of the body to be washed after handling.
		Acute toxicity — dermal (section 3.1)	1, 2
		Skin corrosion (section 3.2)	1A, 1B, 1C
		Skin irritation (section 3.2)	2
		Eye irritation (section 3.3)	2
		Reproductive toxicity — effects on or via lactation (section 3.7)	Additional category
		Specific target organ toxicity — single exposure (section 3.8)	1, 2
		Specific target organ toxicity — repeated exposure (section 3.9)	1
P270	Do not eat, drink or smoke when using this product.	Acute toxicity — oral (section 3.1)	1, 2, 3, 4
		Acute toxicity — dermal (section 3.1)	1, 2
		Reproductive toxicity — effects on or via lactation (section 3.7)	Additional category
		Specific target organ toxicity — single exposure (section 3.8)	1, 2
		Specific target organ toxicity — repeated exposure (section 3.9)	1
P271	Use only outdoors or in a well-ventilated area.	Acute toxicity — inhalation (section 3.1)	1, 2, 3, 4
		Specific target organ toxicity — single exposure; respiratory tract irritation (section 3.8)	3
		Specific target organ toxicity — single exposure; narcosis (section 3.8)	3
[F6 P272	Contaminated work clothing should not be allowed out of the workplace.	Skin sensitisation (section 3.4)	1, 1A, 1B	]
P273	Avoid release to the environment.	Hazardous to the aquatic environment — acute aquatic hazard (section 4.1)	1	if this is not the intended use.
		Hazardous to the aquatic environment — [F6 long-term aquatic hazard (section 4.1)]	1, 2, 3, 4
		[ F7 ]
[F1 P280	Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/…	Explosives (section 2.1)	Unstable explosive and divisions 1.1, 1.2, 1.3, 1.4, 1.5	Manufacturer/supplier to specify the appropriate type of personal protective equipment.
		Flammable gases (section 2.2)	Pyrophoric gas
		Flammable liquids (section 2.6)	1, 2, 3
		Flammable solids (section 2.7)	1, 2
		Self-reactive substances and mixtures (section 2.8)	Types A, B, C, D, E, F
		Pyrophoric liquids (section 2.9)	1
		Pyrophoric solids (section 2.10)	1
		Self-heating substances and mixtures (section 2.11)	1, 2
		Substances and mixtures which, in contact with water, emit flammable gases (section 2.12)	1, 2, 3
		Oxidizing liquids (section 2.13)	1, 2, 3
		Oxidizing solids (section 2.14)	1, 2, 3
		Organic peroxides (section 2.15)	Types A, B, C, D, E, F
		Desensitised explosives (section 2.17)	1, 2, 3, 4
		Acute toxicity – dermal (section 3.1)	1, 2, 3, 4	Specify protective gloves/clothing. Manufacturer/supplier may further specify type of equipment where appropriate.
		Skin corrosion (section 3.2)	1A, 1B, 1C	Specify protective gloves/clothing and eye/face protection. Manufacturer/supplier may further specify type of equipment where appropriate.
		Skin irritation (section 3.2)	2	Specify protective gloves. Manufacturer/supplier may further specify type of equipment where appropriate.
		Skin sensitisation (section 3.4)	1, 1A, 1B
		Serious eye damage (section 3.3)	1	Specify eye/face protection. Manufacturer/supplier may further specify type of equipment where appropriate.
		Eye irritation (section 3.3)	2
		Germ cell mutagenicity (section 3.5)	1A, 1B, 2	Manufacturer/supplier to specify the appropriate type of personal protective equipment.
		Carcinogenicity (section 3.6)	1A, 1B, 2
		Reproductive toxicity (section 3.7)	1A, 1B, 2]
[ F8
F8
F8
F8 ]
[F4 P282	Wear cold insulating gloves and either face shield or eye protection.	Gases under pressure (Section 2.5)	Refrigerated liquefied gas
P283	Wear fire resistant or flame retardant clothing.	Oxidising liquids (Section 2.13)	1
		Oxidising solids (Section 2.14)	1
P284	[In case of inadequate ventilation] wear respiratory protection.	Acute toxicity — inhalation (Section 3.1)	1, 2	— text in square brackets may be used if additional information is provided with the chemical at the point of use that explains what type of ventilation would be adequate for safe use. Manufacturer/supplier to specify equipment.
		Respiratory sensitisation (Section 3.4)	1, 1A, 1B]
[ F8 ]
[F4 P231 + P232	Handle and store contents under inert gas/… Protect from moisture.	Pyrophoric liquids (Section 2.9)	1	… Manufacturer/supplier to specify the appropriate liquid or gas if ‘ inert gas ’ is not appropriate.
		Pyrophoric solids (Section 2.10)	1
		Substances and mixtures which, in contact with water, emit flammable gases (Section 2.12)	1, 2, 3	— if the substance or mixture reacts readily with moisture in air. … Manufacturer/supplier to specify appropriate liquid or gas if ‘ inert gas ’ is not appropriate.]
[ F5 ]

Textual Amendments

F2 Substituted by Commission Regulation (EU) No 487/2013 of 8 May 2013 amending, for the purposes of its adaptation to technical and scientific progress, Regulation (EC) No 1272/2008 of the European Parliament and of the Council on classification, labelling and packaging of substances and mixtures (Text with EEA relevance).

F3 Inserted by Commission Regulation (EU) 2019/521 of 27 March 2019 amending, for the purposes of its adaptation to technical and scientific progress Regulation (EC) No 1272/2008 of the European Parliament and of the Council on classification, labelling and packaging of substances and mixtures (Text with EEA relevance).

F4 Substituted by Commission Regulation (EU) 2016/918 of 19 May 2016 amending, for the purposes of its adaptation to technical and scientific progress, Regulation (EC) No 1272/2008 of the European Parliament and of the Council on classification, labelling and packaging of substances and mixtures (Text with EEA relevance).

F5 Deleted by Commission Regulation (EU) 2016/918 of 19 May 2016 amending, for the purposes of its adaptation to technical and scientific progress, Regulation (EC) No 1272/2008 of the European Parliament and of the Council on classification, labelling and packaging of substances and mixtures (Text with EEA relevance).

F6 Substituted by Commission Regulation (EU) No 286/2011 of 10 March 2011 amending, for the purposes of its adaptation to technical and scientific progress, Regulation (EC) No 1272/2008 of the European Parliament and of the Council on classification, labelling and packaging of substances and mixtures (Text with EEA relevance).

F7 Deleted by Commission Regulation (EU) No 286/2011 of 10 March 2011 amending, for the purposes of its adaptation to technical and scientific progress, Regulation (EC) No 1272/2008 of the European Parliament and of the Council on classification, labelling and packaging of substances and mixtures (Text with EEA relevance).

F8 Deleted by Commission Regulation (EU) No 487/2013 of 8 May 2013 amending, for the purposes of its adaptation to technical and scientific progress, Regulation (EC) No 1272/2008 of the European Parliament and of the Council on classification, labelling and packaging of substances and mixtures (Text with EEA relevance).

Table 6.3

Precautionary statements — Response

Code	Response precautionary statements	Hazard class	Hazard category	Conditions for use
(1)	(2)	(3)	(4)	(5)
[F1 P301	IF SWALLOWED:	Acute toxicity – oral (section 3.1)	1, 2, 3, 4
		Skin corrosion (section 3.2)	1, 1A, 1B, 1C
		Aspiration Hazard (section 3.10)	1
P302	IF ON SKIN:	Pyrophoric liquids (section 2.9)	1
		Pyrophoric solids (section 2.10)	1
		Substances and mixtures which, in contact with water, emit flammable gases (section 2.12)	1, 2
		Acute toxicity – dermal (section 3.1)	1, 2, 3, 4
		Skin irritation (section 3.2)	2
		Skin sensitisation (section 3.4)	1, 1A, 1B]
P303	IF ON SKIN (or hair):	Flammable liquids (section 2.6)	1, 2, 3
		Skin corrosion (section 3.2)	1A, 1B, 1C
[F6 P304	IF INHALED:	Acute toxicity — inhalation (section 3.1)	1, 2, 3, 4
		Skin corrosion (section 3.2)	1A, 1B, 1C
		Respiratory sensitisation (section 3.4)	1, 1A, 1B
		Specific target organ toxicity — single exposure; respiratory tract irritation (section 3.8)	3
		Specific target organ toxicity — single exposure; narcosis (section 3.8)	3]
P305	IF IN EYES:	Skin corrosion (section 3.2)	1A, 1B, 1C
		Serious eye damage/eye irritation (section 3.3)	1
		Eye irritation (section 3.3)	2
P306	IF ON CLOTHING:	Oxidising liquids (section 2.13)	1
		Oxidising solids (section 2.14)	1
[ F8 ]
[F2 P308	IF exposed or concerned:	Germ cell mutagenicity (section 3.5)	1A, 1B, 2
		Carcinogenicity (section 3.6)	1A, 1B, 2
		Reproductive toxicity (section 3.7)	1A, 1B, 2
		Reproductive toxicity — effects on or via lactation (section 3.7)	Additional category
		Specific target organ toxicity, single exposure (section 3.8)	1, 2]
[ F8 ]
[F2 P310	Immediately call a POISON CENTER/doctor/…	Acute toxicity — oral (section 3.1)	1, 2, 3	…Manufacturer/supplier to specify the appropriate source of emergency medical advice.
		Acute toxicity — dermal (section 3.1)	1, 2
		Acute toxicity — inhalation (section 3.1)	1, 2
		Skin corrosion (section 3.2)	1A, 1B, 1C
		Serious eye damage/eye irritation (section 3.3)	1
		Aspiration hazard (section 3.10)	1
P311	Call a POISON CENTER/doctor/…	Acute toxicity — inhalation (section 3.1)	3	…Manufacturer/supplier to specify the appropriate source of emergency medical advice.
		Respiratory sensitisation (section 3.4)	1, 1A, 1B
		Specific target organ toxicity — single exposure (section 3.8)	1, 2
[F4 P312	Call a POISON CENTRE/doctor/… if you feel unwell.	Acute toxicity — oral (Section 3.1)	4	… Manufacturer/supplier to specify the appropriate source of emergency medical advice.
		Acute toxicity — dermal (Section 3.1)	3, 4
		Acute toxicity — inhalation (Section 3.1)	4
		Specific target organ toxicity — single exposure; respiratory tract irritation (Section 3.8)	3
		Specific target organ toxicity — single exposure; narcotic effects (Section 3.8)	3] ]
[F6 P313	Get medical advice/attention.	Skin irritation (section 3.2)	2, 3
		Eye irritation (section 3.3)	2
		Skin sensitisation (section 3.4)	1, 1A, 1B
		Germ cell mutagenicity (section 3.5)	1A, 1B, 2
		Carcinogenicity (section 3.6)	1A, 1B, 2
		Reproductive toxicity (section 3.7)	1A, 1B, 2
		Reproductive toxicity — effects on or via lactation (section 3.7)	Additional category]
P314	Get medical advice/attention if you feel unwell.	Specific target organ toxicity — repeated exposure (section 3.9)	1, 2
P315	Get immediate medical advice/attention.	Gases under pressure (section 2.5)	Refrigerated liquefied gas
[F4 P320	Specific treatment is urgent (see … on this label).	Acute toxicity — inhalation (Section 3.1)	1, 2	— if immediate administration of antidote is required. … Reference to supplemental first aid instruction.
P321	Specific treatment (see … on this label).	Acute toxicity — oral (Section 3.1)	1, 2, 3	— if immediate administration of antidote is required. … Reference to supplemental first aid instruction.
		Acute toxicity, dermal (Section 3.1)	1, 2, 3, 4	— if immediate measures such as specific cleansing agent are advised. … Reference to supplemental first aid instruction.
		Acute toxicity — inhalation (Section 3.1)	3	— if immediate specific measures are required. … Reference to supplemental first aid instruction.
		Skin corrosion (Section 3.2)	1, 1A, 1B, 1C	… Reference to supplemental first aid instruction. Manufacturer/supplier may specify a cleansing agent if appropriate.
		Skin irritation (Section 3.2)	2
		Skin sensitisation (Section 3.4)	1, 1A, 1B
		Specific target organ toxicity — single exposure (Section 3.8)	1	— if immediate measures are required. … Reference to supplemental first aid instruction.]
[ F8
F8 ]
P330	Rinse mouth.	Acute toxicity — oral (section 3.1)	1, 2, 3, 4
		Skin corrosion (section 3.2)	1A, 1B, 1C
P331	Do NOT induce vomiting.	Skin corrosion (section 3.2)	1A, 1B, 1C
		Aspiration hazard (section 3.10)	1
[F1 P332	If skin irritation occurs:	Skin irritation (section 3.2)	2	may be omitted if P333 is given on the label.]
[F6 P333	If skin irritation or rash occurs:	Skin sensitisation (section 3.4)	1, 1A, 1B	]
[F4 P334	Immerse in cool water [or wrap in wet bandages].	Pyrophoric liquids (Section 2.9)	1	— text in square brackets to be used for pyrophoric liquids and solids
		Pyrophoric solids (Section 2.10)	1
		Substances and mixtures which, in contact with water, emit flammable gases (Section 2.12)	1, 2	Use only ‘ immerse in cool water. ’ Text in square brackets should not be used.]
P335	Brush off loose particles from skin.	Pyrophoric solids (section 2.10)	1
		Substances and mixtures which, in contact with water, emit flammable gases (section 2.12)	1, 2
P336	Thaw frosted parts with lukewarm water. Do not rub affected area.	Gases under pressure (section 2.5)	Refrigerated liquefied gas
P337	If eye irritation persists:	Eye irritation (section 3.3)	2
P338	Remove contact lenses, if present and easy to do. Continue rinsing.	Skin corrosion (section 3.2)	1A, 1B, 1C
		Serious eye damage/eye irritation (section 3.3)	1
		Eye irritation (section 3.3)	2
[F2 P340	Remove person to fresh air and keep comfortable for breathing.	Acute toxicity — inhalation (section 3.1)	1, 2, 3, 4
		Skin corrosion (section 3.2)	1A, 1B, 1C
		Respiratory sensitisation (section 3.4)	1, 1A, 1B
		Specific target organ toxicity — single exposure; respiratory tract irritation (section 3.8)	3
		Specific target organ toxicity — single exposure; narcosis (section 3.8)	3]
[ F8 ]
[F6 P342	If experiencing respiratory symptoms:	Respiratory sensitisation (section 3.4)	1, 1A, 1B	]
[ F8 ]
P351	Rinse cautiously with water for several minutes.	Skin corrosion (section 3.2)	1A, 1B, 1C
		Serious eye damage/eye irritation (section 3.3)	1
		Eye irritation (section 3.3)	2
[F2 P352	Wash with plenty of water/…	Acute toxicity — dermal (section 3.1)	1, 2, 3, 4	…Manufacturer/supplier may specify a cleansing agent if appropriate, or may recommend an alternative agent in exceptional cases if water is clearly inappropriate.
		Skin irritation (section 3.2)	2
		Skin sensitisation (section 3.4)	1, 1A, 1B]
[F4 P353	Rinse skin with water [or shower].	Flammable liquids (Section 2.6)	1, 2, 3	— text in square brackets to be included where the manufacturer/supplier considers it appropriate for the specific chemical.
		Skin corrosion (Section 3.2)	1, 1A, 1B, 1C]
P360	Rinse immediately contaminated clothing and skin with plenty of water before removing clothes.	Oxidising liquids (section 2.13)	1
		Oxidising solids (section 2.14)	1
[F2 P361	Take off immediately all contaminated clothing.	Flammable liquids (section 2.6)	1, 2, 3
		Acute toxicity — dermal (section 3.1)	1, 2, 3
		Skin corrosion (section 3.2)	1A, 1B, 1C
P362	Take off contaminated clothing.	Acute toxicity, dermal (section 3.1)	4
		Skin irritation (section 3.2)	2
		Skin sensitisation (section 3.4)	1, 1A, 1B
P363	Wash contaminated clothing before reuse.	Skin corrosion (section 3.2)	1A, 1B, 1C	]
[F9 P364	And wash it before reuse.	Acute toxicity, dermal (section 3.1)	1, 2, 3, 4
		Skin irritation (section 3.2)	2
		Skin sensitisation (section 3.4)	1, 1A, 1B	]
[F1 P370	In case of fire:	Explosives (section 2.1)	Unstable explosives and divisions 1.1, 1.2, 1.3, 1.4, 1.5
		Oxidising gases (section 2.4)	1
		Flammable liquids (section 2.6)	1, 2, 3
		Flammable solids (section 2.7)	1, 2
		Self-reactive substances and mixtures (section 2.8)	Types A, B, C, D, E, F
		Pyrophoric liquids (section 2.9)	1
		Pyrophoric solids (section 2.10)	1
		Substances and mixtures which, in contact with water, emit flammable gases (section 2.12)	1, 2, 3
		Oxidising liquids (section 2.13)	1, 2, 3
		Oxidising solids (section 2.14)	1, 2, 3
		Organic Peroxides (section 2.15)	Types A, B, C, D, E, F
		Desensitised explosives (section 2.17)	1, 2, 3
P371	In case of major fire and large quantities:	Oxidising liquids (section 2.13)	1
		Oxidising solids (section 2.14)	1
		Desensitised explosives (section 2.17)	4	]
[F4 P372	Explosion risk.	Explosives (Section 2.1)	Unstable explosives and Divisions 1.1, 1.2, 1.3, and 1.5
			Division 1.4	— except for explosives of division 1.4 (compatibility group S) in transport packaging.
		Self-reactive substances and mixtures (Section 2.8)	Type A
		Organic peroxides (Section 2.15)	Type A
P373	DO NOT fight fire when fire reaches explosives.	Explosives (Section 2.1)	Unstable explosives and Divisions 1.1, 1.2, 1.3, 1.5
			Division 1.4	— except for explosives of division 1.4 (compatibility group S) in transport packaging.
		Self-reactive substances and mixtures (Section 2.8)	Type A
		Organic peroxides (Section 2.15)	Type A]
[ F5 ]
[F1 P375	Fight fire remotely due to the risk of explosion.	Explosives (section 2.1)	Division 1.4	for explosives of division 1.4 (compatibility group S) in transport packaging.
		Self-reactive substances and mixtures (section 2.8)	Type B
		Oxidising liquids (section 2.13)	1
		Oxidising solids (section 2.14)	1
		Organic peroxides (section 2.15)	Type B
		Desensitised explosives (section 2.17)	1, 2, 3, 4]
P376	Stop leak if safe to do so.	Oxidising gases (section 2.4)	1
[F1 P377	Leaking gas fire: Do not extinguish, unless leak can be stopped safely.	Flammable gases (section 2.2)	1A, 1B, 2	]
[F4 P378	Use … to extinguish.	Flammable liquids (Section 2.6)	1, 2, 3	— if water increases risk … Manufacturer/supplier to specify appropriate media
		Flammable solids (Section 2.7)	1, 2
		Self-reactive substances and mixtures (Section 2.8)	Types B, C, D, E, F
		Pyrophoric liquids (Section 2.9)	1
		Pyrophoric solids (Section 2.10)	1
		Substances and mixtures which, in contact with water, emit flammable gases (Section 2.12)	1, 2, 3
		Oxidising liquids (Section 2.13)	1, 2, 3
		Oxidising solids (Section 2.14)	1, 2, 3
		Organic peroxides (Section 2.15)	Types B, C, D, E, F
[F1 P380	Evacuate area.	Explosives (section 2.1)	Unstable explosives and Divisions 1.1, 1.2, 1.3, 1.4, 1.5
		Self-reactive substances and mixtures (section 2.8)	Types A, B
		Oxidising liquids (section 2.13)	1
		Oxidising solids (section 2.14)	1
		Organic peroxides (section 2.15)	Types A, B
		Desensitised explosives (section 2.17)	1, 2, 3, 4	]
[F1 P381	In case of leakage, eliminate all ignition sources	Flammable gases (section 2.2)	1A, 1B, 2	] ]
P390	Absorb spillage to prevent material damage.	Corrosive to metals (section 2.16)	1
P391	Collect spillage.	Hazardous to the aquatic environment – acute aquatic hazard (section 4.1)	1
		Hazardous to the aquatic environment – [F6 long-term aquatic hazard (section 4.1)]	1, 2
[F2 P301 + P310	IF SWALLOWED: Immediately call a POISON CENTER/doctor/…	Acute toxicity — oral (section 3.1)	1, 2, 3	…Manufacturer/supplier to specify the appropriate source of emergency medical advice.
		Aspiration hazard (section 3.10)	1
[F1 P301 + P312	IF SWALLOWED: Call a POISON CENTER/doctor/… if you feel unwell	Acute toxicity – oral (section 3.1)	4	… Manufacturer/supplier to specify the appropriate source of emergency medical advice] ]
[ F5 ]
[F4 P302 + P334	IF ON SKIN: Immerse in cool water or wrap in wet bandages.	Pyrophoric liquids (Section 2.9)	1	]
[ F8 ]
[F2 P302 + P352	IF ON SKIN: Wash with plenty of water/…	Acute toxicity — dermal (section 3.1)	1, 2, 3, 4	…Manufacturer/supplier may specify a cleansing agent if appropriate, or may recommend an alternative agent in exceptional cases if water is clearly inappropriate.
		Skin irritation (section 3.2)	2
		Skin sensitisation (section 3.4)	1, 1A, 1B]
[ F5
F5 ]
[F2 P304 + P340	IF INHALED: Remove person to fresh air and keep comfortable for breathing.	Acute toxicity — inhalation (section 3.1)	1, 2, 3, 4
		Skin corrosion (section 3.2)	1A, 1B, 1C
		Respiratory sensitisation (section 3.4)	1, 1A, 1B
		Specific target organ toxicity — single exposure; respiratory tract irritation (section 3.8)	3
		Specific target organ toxicity — single exposure; narcosis (section 3.8)	3]
[ F8 ]
[ F5
F5
F5 ]
P306 + P360	IF ON CLOTHING: Rinse immediately contaminated clothing and skin with plenty of water before removing clothes.	Oxidising liquids (section 2.13)	1
		Oxidising solids (section 2.14)	1
[F2 P308 + P311	IF exposed or concerned: Call a POISON CENTER/doctor/…	Specific target organ toxicity — single exposure (section 3.8)	1, 2	…Manufacturer/supplier to specify the appropriate source of emergency medical advice.]
P308 + P313	IF exposed or concerned: Get medical advice/attention.	Germ cell mutagenicity (section 3.5)	1A, 1B, 2
		Carcinogenicity (section 3.6)	1A, 1B, 2
		Reproductive toxicity (section 3.7)	1A, 1B, 2
		Reproductive toxicity — effects on or via lactation (section 3.7)	Additional category
[ F8 ]
[F4 P332 + P313	If skin irritation occurs: Get medical advice/attention.	Skin irritation (Section 3.2)	2	— may be omitted when P333 + P313 is given on the label.]
[F6 P333 + P313	If skin irritation or rash occurs: Get medical advice/attention.	Skin sensitisation (section 3.4)	1, 1A, 1B	]
[F10 P336 + P315	Thaw frosted parts with lukewarm water. Do not rub affected area. Get immediate medical advice/attention.	Gases under pressure (Section 2.5)	Refrigerated liquefied gas	]
[ F5
F5 ]
P337 + P313	If eye irritation persists: Get medical advice/attention.	Eye irritation (section 3.3)	2
[F2 P342 + P311	If experiencing respiratory symptoms: Call a POISON CENTER/doctor/…	Respiratory sensitisation (section 3.4)	1, 1A, 1B	…Manufacturer/supplier to specify the appropriate source of emergency medical advice.]
[F9 P361 + P364	Take off immediately all contaminated clothing and wash it before reuse.	Acute toxicity, dermal (section 3.1)	1, 2, 3
P362 + P364	Take off contaminated clothing and wash it before reuse.	Acute toxicity, dermal (section 3.1)	4
		Skin irritation (section 3.2)	2
		Skin sensitisation (section 3.4)	1, 1A, 1B]
P370 + P376	In case of fire: Stop leak if safe to do so.	Oxidizing gases (section 2.4)	1
[F4 P370 + P378	In case of fire: Use … to extinguish.	Flammable liquids (Section 2.6)	1, 2, 3	— if water increases risk. … Manufacturer/sup-plier to specify appropriate media.
		Flammable solids (Section 2.7)	1, 2
		Self-reactive substances and mixtures (Section 2.8)	Types C, D, E, F
		Pyrophoric liquids (Section 2.9)	1
		Pyrophoric solids (Section 2.10)	1
		Substances and mixtures which, in contact with water, emit flammable gases (Section 2.12)	1, 2, 3
		Oxidising liquids (Section 2.13)	1, 2, 3
		Oxidising solids (Section 2.14)	1, 2, 3
		Organic peroxides (Section 2.15)	Types C, D, E, F]
[F10 P301 + P330 + P331	IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.	Skin corrosion (Section 3.2)	1, 1A, 1B, 1C
P302 + P335 + P334	IF ON SKIN: Brush off loose particles from skin. Immerse in cool water [or wrap in wet bandages].	Pyrophoric solids (Section 2.10)	1	— text in square brackets to be used for pyrophoric solids
		Substances and mixtures which, in contact with water, emit flammable gases (Section 2.12)	1, 2	— use only ‘ Immerse in cold water ’ . Text in square brackets should not be used.
P303 + P361 + P353	IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water [or shower].	Flammable liquids (Section 2.6)	1, 2, 3	— text in square brackets to be included where the manufacturer/supplier considers it appropriate for the specific chemical.
		Skin corrosion (Section 3.2)	1, 1A, 1B, 1C
P305 + P351 + P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.	Skin corrosion (Section 3.2)	1, 1A, 1B, 1C
		Serious eye damage/eye irritation (Section 3.3)	1
		Eye irritation (Section 3.3)	2	]
[ F5 ]
[F1 P370 + P380 + P375	In case of fire: Evacuate area. Fight fire remotely due to the risk of explosion.	Explosives (section 2.1)	Division 1.4	for explosives of division 1.4 (compatibility group S) in transport packaging
		Desensitised explosives (section 2.17)	1, 2, 3
P371 + P380 + P375	In case of major fire and large quantities: Evacuate area. Fight fire remotely due to the risk of explosion.	Oxidising liquids (section 2.13)	1
		Oxidising solids (section 2.14)	1
		Desensitised explosives (section 2.17)	4]
[F10 P370 + P372 + P380 + P373	In case of fire: Explosion risk. Evacuate area. DO NOT fight fire when fire reaches explosives	Explosives (Section 2.1)	Unstable explosives and divisions 1.1, 1.2, 1.3, 1.5
			Division 1.4	— except for explosives of division 1.4 (compatibility group S) in transport packaging.
		Self-reactive substances and mixtures (Section 2.8)	Type A
		Organic peroxides (Section 2.15)	Type A
P370 + P380 + P375 + [P378]	In case of fire: Evacuate area. Fight fire remotely due to the risk of explosion. [Use … to extinguish].	Self-reactive substances and mixtures (Section 2.8)	Type B	— text in square brackets to be used if water increases risk. … Manufacturer/supplier to specify appropriate media.
		Organic peroxides (Section 2.15)	Type B]

Textual Amendments

F9 Inserted by Commission Regulation (EU) No 487/2013 of 8 May 2013 amending, for the purposes of its adaptation to technical and scientific progress, Regulation (EC) No 1272/2008 of the European Parliament and of the Council on classification, labelling and packaging of substances and mixtures (Text with EEA relevance).

F10 Inserted by Commission Regulation (EU) 2016/918 of 19 May 2016 amending, for the purposes of its adaptation to technical and scientific progress, Regulation (EC) No 1272/2008 of the European Parliament and of the Council on classification, labelling and packaging of substances and mixtures (Text with EEA relevance).

Table 6.4

Precautionary statements — Storage

Code	Storage precautionary statements	Hazard class	Hazard category	Conditions for use
(1)	(2)	(3)	(4)	(5)
[F1 P401	Store in accordance with …	Explosives (section 2.1)	Unstable explosives and Divisions 1.1, 1.2, 1.3, 1.4, 1.5	… Manufacturer/supplier to specify local/regional/national/international regulations as applicable.
		Desensitised explosives (section 2.17)	1, 2, 3, 4]
P402	Store in a dry place.	Substances and mixtures which, in contact with water, emit flammable gases (section 2.12)	1, 2, 3
[F1 P403	Store in a well-ventilated place.	Flammable gases (section 2.2)	1A, 1B, 2
		Oxidising gases (section 2.4)	1
		Gases under pressure (section 2.5)	Compressed gas
			Liquefied gas
			Refrigerated liquefied gas
			Dissolved gas
		Flammable liquids (section 2.6)	1, 2, 3	for flammable liquids Category 1 and other flammable liquids that are volatile and may generate an explosive atmosphere.
		Self-reactive substances and mixtures (section 2.8)	Types A, B, C, D, E, F	except for temperature controlled self-reactive substances and mixtures or organic peroxides because condensation and consequent freezing may take place.
		Organic peroxides (section 2.15)
		Acute toxicity – inhalation (section 3.1)	1, 2, 3	if the substance or mixture is volatile and may generate a hazardous atmosphere.
		Specific target organ toxicity – single exposure; respiratory tract irritation (section 3.8)	3
		Specific target organ toxicity – single exposure; narcotic effects (section 3.8)	3]
P404	Store in a closed container.	Substances and mixtures which, in contact with water, emit flammable gases (section 2.12)	1, 2, 3
P405	Store locked up.	Acute toxicity — oral (section 3.1)	1, 2, 3
		Acute toxicity — dermal (section 3.1)	1, 2, 3
		Acute toxicity — inhalation (section 3.1)	1, 2, 3
		Skin corrosion (section 3.2)	1A, 1B, 1C
		Germ cell mutagenicity (section 3.5)	1A, 1B, 2
		Carcinogenicity (section 3.6)	1A, 1B, 2
		Reproductive toxicity (section 3.7)	1A, 1B, 2
		Specific target organ toxicity — single exposure (section 3.8)	1, 2
		Specific target organ toxicity — single exposure; respiratory tract irritation (section 3.8)	3
		Specific target organ toxicity — single exposure; narcosis (section 3.8)	3
		Aspiration hazard (section 3.10)	1
[F4 P406	Store in a corrosion-resistant/… container with a resistant inner liner.	Corrosive to metals (Section 2.16)	1	— may be omitted if P234 is given on the label … Manufacturer/supplier to specify other compatible materials.]
[F4 P407	Maintain air gap between stacks or pallets.	Self-heating substances and mixtures (Section 2.11)	1, 2	]
[F2 P410	Protect from sunlight.	Aerosols (section 2.3)	1,2, 3
		Gases under pressure (section 2.5)	Compressed gas Liquefied gas Dissolved gas	— may be omitted for gases filled in transportable gas cylinders in accordance with packing instruction P200 of the UN RTDG, Model Regulations, unless those gases are subject to (slow) decomposition or polymerisation
		Self-heating substances and mixtures (section 2.11)	1, 2
		Organic peroxides (section 2.15)	Types A, B, C, D, E, F	]
[F4 P411	Store at temperatures not exceeding … °C/… °F.	Self-reactive substances and mixtures (Section 2.8)	Types A, B, C, D, E, F	— if temperature control is required (according to Annex I, Section 2.8.2.4 or 2.15.2.3) or if otherwise deemed necessary. … Manufacturer/supplier to specify temperature using the applicable temperature scale.
		Organic peroxides (Section 2.15)	Types A, B, C, D, E, F
P412	Do not expose to temperatures exceeding 50 °C/ 122 °F.	Aerosols (Section 2.3)	1, 2, 3	Manufacturer/supplier to use applicable temperature scale.
P413	Store bulk masses greater than … kg/… lbs at temperatures not exceeding … °C/… °F.	Self-heating substances and mixtures (Section 2.11)	1, 2	… Manufacturer/supplier to specify mass and temperature using applicable scale.
P420	Store separately.	Self-reactive substances and mixtures (Section 2.8)	Types A, B, C, D, E, F
		Self-heating substances and mixtures (Section 2.11)	1,2
		Oxidising liquids (Section 2.13)	1
		Oxidising solids (Section 2.14)	1
		Organic peroxides (Section 2.15)	Types A,B,C,D,E,F]
[ F5
F5 ]
P402 + P404	Store in a dry place. Store in a closed container.	Substances and mixtures which, in contact with water, emit flammable gases (section 2.12)	1, 2, 3
[F4 P403 + P233	Store in a well-ventilated place. Keep container tightly closed.	Acute toxicity — inhalation (Section 3.1)	1, 2, 3	— if the substance or mixture is volatile and may generate a hazardous atmosphere.
		Specific target organ toxicity — single exposure; respiratory tract irritation (Section 3.8)	3
		Specific target organ toxicity — single exposure; narcosis (Section 3.8)	3
P403 + P235	Store in a well-ventilated place. Keep cool.	Flammable liquids (Section 2.6)	1, 2, 3	— for flammable liquids Category 1 and other flammable liquids that are volatile and may generate an explosive atmosphere.
P410 + P403	Protect from sunlight. Store in a well-ventilated place.	Gases under pressure (Section 2.5)	Compressed gas	— P410 may be omitted for gases filled in transportable gas cylinders in accordance with packing instruction P200 of the UN RTDG, unless those gases are subject to (slow) decomposition or polymerisation.
			Liquefied gas
			Dissolved gas
P410 + P412	Protect from sunlight. Do not expose to temperatures exceeding 50 °C/122 °F.	Aerosols (Section 2.3)	1, 2, 3	Manufacturer/ supplier to use applicable temperature scale.]
[ F5 ]

[F6 Table 6.5

Precautionary statements — Disposal

Code	Disposal precautionary statements	Hazard class	Hazard category	Conditions for use
(1)	(2)	(3)	(4)	(5)
[F1 P501	Dispose of contents/container to …	Flammable liquids (section 2.6)	1, 2, 3	… in accordance with local/regional/national/international regulation (to be specified). Manufacturer/supplier to specify whether disposal requirements apply to contents, container or both.
		Self-reactive substances and mixtures (section 2.8)	Types A, B, C, D, E, F
		Substances and mixtures which, in contact with water, emit flammable gases (section 2.12)	1, 2, 3
		Oxidising liquids (section 2.13)	1, 2, 3
		Oxidising solids (section 2.14)	1, 2, 3
		Organic peroxides (section 2.15)	Types A, B, C, D, E, F
		Desensitised explosives (section 2.17)	1, 2, 3, 4
		Acute toxicity – oral (section 3.1)	1, 2, 3, 4
		Acute toxicity – dermal (section 3.1)	1, 2, 3, 4
		Acute toxicity – inhalation (section 3.1)	1, 2, 3
		Skin corrosion (section 3.2)	1, 1A, 1B, 1C
		Respiratory sensitisation (section 3.4)	1, 1A, 1B
		Skin sensitisation (section 3.4)	1, 1A, 1B
		Germ cell mutagenicity (section 3.5)	1A, 1B, 2
		Carcinogenicity (section 3.6)	1A, 1B, 2
		Reproductive toxicity (section 3.7)	1A, 1B, 2
		Specific target organ toxicity – single exposure (section 3.8)	1, 2
		Specific target organ toxicity – single exposure; respiratory tract irritation (section 3.8)	3
		Specific target organ toxicity – single exposure; narcotic effects (section 3.8)	3
		Specific target organ toxicity – repeated exposure (section 3.9)	1, 2
		Aspiration hazard (section 3.10)	1
		Hazardous to the aquatic environment – acute aquatic hazard (section 4.1)	1
		Hazardous to the aquatic environment – chronic aquatic hazard (section 4.1)	1, 2, 3, 4]
[F4 P502	Refer to manufacturer or supplier for information on recovery or recycling	Hazardous to the ozone layer (Section 5.1)	1	]
[F3 P503	Refer to manufacturer/ supplier/… for information on disposal/recovery/ recycling	Explosives (section 2.1)	Unstable explosives and Divisions 1.1, 1.2, 1.3, 1.4, 1.5	… Manufacturer/supplier to specify appropriate source of information in accordance with local/regional/national/international regulations as applicable.] ]