Misuse of Drugs Act 1971

1 U.K. The following substances and products, namely:—

[F1 (a)]

• Acetyldihydrocodeine.

• Amphetamine.

• [F2 N-Benzyl-ethylphenidate.]

• [F3 1,4-Butanediol.]

• [F4 Cannabinol]

• [F4 Cannabinol derivatives]

• [F4 Cannabis and cannabis resin]

• F5 ...

• Codeine.

• [F6 Cumyl-PeGaClone.]

• F7 ...

• Dihydrocodeine.

• [F8 Diphenidine.

• Ephenidine.]

• Ethylmorphine (3-ethylmorphine).

• [F9 Ethylnaphthidate.

• Ethylphenidate.]

• [F10 Gamma-butyrolactone.]

• [F11 Glutethimide.]

• [F12 4-Hydroxy-n-butyric acid.]

• [F13 Isopropylphenidate (IPP or IPPD).]

• [F14 Ketamine.]

• [F11 Lefetamine.]

• [F15 Lisdexamphetamine.]

• [F16 Mecloqualone.]

• [F16 Methaqualone.]

• [F17 Methcathinone]

• [F18 Methoxyphenidine.]

• [F19 Methylmorphenate

• Methylnaphthidate (HDMP-28).]

• F20 ...

• F21 ...

• [F22 a-Methylphenethylhydroxylamine]

• Methylphenidate.

• [F16 Methylphenobarbitone.]

• [F23 N-methyl-1-(thiophen-2-yl)propan-2-amine (methiopropamine or MPA).]

• Nicocodine.

• [F24 Nicodicodine (6-nicotinoyldihydrocodeine).]

• Norcodeine.

• [F25 Pentazocine.]

• Phenmetrazine.

• Pholcodine.

• [F26 Propiram.]

• [F27 Propylphenidate.]

• [F17 Zipeprol]

• [F28 3,4-Dichloroethylphenidate.

• 3,4-Dichloromethylphenidate (3,4-DCMP).]

• [F29 2-((Dimethylamino)methyl)-1-(3-hydroxyphenyl)cyclohexanol.]

• [F30 4-Fluoroethylphenidate.

• 4-Fluoromethylphenidate.

• 4-Methylmethylphenidate.]

[F31 (aa) Any compound (not being bupropion, cathinone, diethylpropion, pyrovalerone or a compound for the time being specified in sub–paragraph (a) above) structurally derived from 2–amino–1–phenyl–1–propanone by modification in any of the following ways, that is to say,

(i) by substitution in the phenyl ring to any extent with alkyl, alkoxy, alkylenedioxy, haloalkyl or halide substituents, whether or not further substituted in the phenyl ring by one or more other univalent substituents;

(ii) by substitution at the 3–position with an alkyl substituent;

(iii) by substitution at the nitrogen atom with alkyl or dialkyl groups, or by inclusion of the nitrogen atom in a cyclic structure.]

[F32 (ab) Any compound structurally derived from 2–aminopropan–1–one by substitution at the 1-position with any monocyclic, or fused‑polycyclic ring system (not being a phenyl ring or alkylenedioxyphenyl ring system), whether or not the compound is further modified in any of the following ways, that is to say,

(i) by substitution in the ring system to any extent with alkyl, alkoxy, haloalkyl or halide substituents, whether or not further substituted in the ring system by one or more other univalent substituents;

(ii) by substitution at the 3–position with an alkyl substituent;

(iii) by substitution at the 2‑amino nitrogen atom with alkyl or dialkyl groups, or by inclusion of the 2-amino nitrogen atom in a cyclic structure.]

[F33 (ac) Any compound (not being pipradrol) structurally derived from piperidine, pyrrolidine, azepane, morpholine or pyridine by substitution at a ring carbon atom with a diphenylmethyl group, whether or not the compound is further modified in any of the following ways, that is to say,

(i) by substitution in any of the phenyl rings to any extent with alkyl, alkoxy, haloalkyl or halide groups;

(ii) by substitution at the methyl carbon atom with an alkyl, hydroxyalkyl or hydroxy group;

(iii) by substitution at the ring nitrogen atom with an alkyl, alkenyl, haloalkyl or hydroxyalkyl group.]

[F1 (b) any 5,5 disubstituted barbituric acid.]

[F34 (c) [2,3–Dihydro–5–methyl–3–(4–morpholinylmethyl)pyrrolo[1, 2, 3–de]–1,4–benzoxazin–6–yl]–1–naphthalenylmethanone.

• [9–Hydroxy–6–methyl–3–[5–phenylpentan–2–yl] oxy–5, 6, 6a, 7, 8, 9, 10, 10a–octahydrophenanthridin–1–yl] acetate.

• [9–Hydroxy–6–methyl–3–[5–phenylpentan–2–yl] oxy–5, 6, 6a, 7, 8, 9, 10, 10a–octahydrophenanthridin–1–yl] acetate.

• 9-(Hydroxymethyl)–6, 6–dimethyl–3–(2–methyloctan–2–yl)–6a, 7, 10, 10a–tetrahydrobenzo[c]chromen–1–ol.

• Any compound structurally derived from 3–(1–naphthoyl)indole, 3-(2-naphthoyl) indole, 1H–indol–3–yl–(1–naphthyl)methane or 1H-indol-3-yl-(2-naphthyl)methane by substitution at the nitrogen atom of the indole ring by alkyl, haloalkyl, alkenyl, cyanoalkyl, hydroxyalkyl, cycloalkylmethyl, cycloalkylethyl, (N-methylpiperidin-2-yl)methyl or 2–(4–morpholinyl)ethyl, whether or not further substituted in the indole ring to any extent and whether or not substituted in the naphthyl ring to any extent.

• Any compound structurally derived from 3–(1–naphthoyl)pyrrole or 3-(2-naphthoyl)pyrrole by substitution at the nitrogen atom of the pyrrole ring by alkyl, haloalkyl, alkenyl, cyanoalkyl, hydroxyalkyl, cycloalkylmethyl, cycloalkylethyl, (N-methylpiperidin-2-yl)methyl or 2–(4–morpholinyl)ethyl, whether or not further substituted in the pyrrole ring to any extent and whether or not substituted in the naphthyl ring to any extent.

• Any compound structurally derived from 1–(1–naphthylmethylene)indene or 1-(2-naphthylmethylene)indene by substitution at the 3–position of the indene ring by alkyl, haloalkyl, alkenyl, cyanoalkyl, hydroxyalkyl, cycloalkylmethyl, cycloalkylethyl, (N-methylpiperidin-2-yl)methyl or 2–(4–morpholinyl)ethyl, whether or not further substituted in the indene ring to any extent and whether or not substituted in the naphthyl ring to any extent.

• Nabilone.

• Any compound structurally derived from 3–phenylacetylindole by substitution at the nitrogen atom of the indole ring by alkyl, haloalkyl, alkenyl, cyanoalkyl, hydroxyalkyl, cycloalkylmethyl, cycloalkylethyl, (N-methylpiperidin-2-yl)methyl or 2–(4–morpholinyl)ethyl, whether or not further substituted in the indole ring to any extent and whether or not substituted in the phenyl ring to any extent.

• Any compound structurally derived from 2–(3–hydroxycyclohexyl)phenol by substitution at the 5–position of the phenolic ring by alkyl, alkenyl, cycloalkylmethyl, cycloalkylethyl or 2–(4–morpholinyl)ethyl, whether or not further substituted in the cyclohexyl ring to any extent.

• Any compound structurally derived from 3-benzoylindole by substitution at the nitrogen atom of the indole ring by alkyl, haloalkyl, alkenyl, cyanoalkyl, hydroxyalkyl, cycloalkylmethyl, cycloalkylethyl, (N-methylpiperidin-2-yl)methyl or 2–(4–morpholinyl)ethyl, whether or not further substituted in the indole ring to any extent and whether or not substituted in the phenyl ring to any extent.

• Any compound structurally derived from 3-(1-adamantoyl)indole or 3-(2-adamantoyl)indole by substitution at the nitrogen atom of the indole ring by alkyl, haloalkyl, alkenyl, cyanoalkyl, hydroxyalkyl, cycloalkylmethyl, cycloalkylethyl, (N-methylpiperidin-2-yl)methyl or 2–(4–morpholinyl)ethyl, whether or not further substituted in the indole ring to any extent and whether or not substituted in the adamantyl ring to any extent.

• Any compound structurally derived from 3-(2,2,3,3-tetramethylcyclopropylcarbonyl)indole by substitution at the nitrogen atom of the indole ring by alkyl, haloalkyl, alkenyl, cyanoalkyl, hydroxyalkyl, cycloalkylmethyl, cycloalkylethyl, (N-methylpiperidin-2-yl)methyl or 2–(4–morpholinyl)ethyl, whether or not further substituted in the indole ring to any extent.

[F35 (ca) [F36 any compound (not being a compound for the time being specified in sub-paragraph (c) above) structurally related to 1-pentyl-3-(1-naphthoyl)indole (JWH-018), in that the four sub-structures, that is to say the indole ring, the pentyl substituent, the methanone linking group and the naphthyl ring, are linked together in a similar manner, whether or not any of the sub-structures have been modified, and whether or not substituted in any of the linked sub-structures with a benzyl or phenyl group and whether or not such compound is further substituted to any extent with alkyl, alkenyl, alkoxy, halide, haloalkyl or cyano substituents and, where any of the sub-structures have been modified, the modifications of the sub-structures are limited to any of the following, that is to say—]

(i) replacement of the indole ring with indane, indene, indazole, pyrrole, pyrazole, imidazole, benzimidazole, pyrrolo[2,3-b]pyridine, pyrrolo[3,2-c]pyridine or pyrazolo[3,4‑b]pyridine;

(ii) replacement of the pentyl substituent with alkyl, alkenyl, benzyl, cycloalkylmethyl, cycloalkylethyl, (N-methylpiperidin-2-yl)methyl, 2-(4-morpholinyl)ethyl or (tetrahydropyran-4-yl)methyl;

(iii) replacement of the methanone linking group with an ethanone, carboxamide, carboxylate, methylene bridge or methine group;

(iv) replacement of the 1-naphthyl ring with 2-naphthyl, phenyl, benzyl, adamantyl, cycloalkyl, cycloalkylmethyl, cycloalkylethyl, bicyclo[2.2.1]heptanyl, 1,2,3,4-tetrahydronaphthyl, quinolinyl, isoquinolinyl, 1-amino-1-oxopropan-2-yl, 1‑hydroxy-1-oxopropan-2-yl, piperidinyl, morpholinyl, pyrrolidinyl, tetrahydropyranyl or piperazinyl.]

(d) 1-Phenylcyclohexylamine or any compound (not being ketamine, tiletamine or a compound for the time being specified in paragraph 1(a) of Part 1 of this Schedule) structurally derived from 1-phenylcyclohexylamine or 2-amino-2-phenylcyclohexanone by modification in any of the following ways, that is to say,

(i) by substitution at the nitrogen atom to any extent by alkyl, alkenyl or hydroxyalkyl groups, or replacement of the amino group with a 1-piperidyl, 1-pyrrolidyl or 1-azepyl group, whether or not the nitrogen containing ring is further substituted by one or more alkyl groups;

(ii) by substitution in the phenyl ring to any extent by amino, alkyl, hydroxy, alkoxy or halide substituents, whether or not further substituted in the phenyl ring to any extent;

(iii) by substitution in the cyclohexyl or cyclohexanone ring by one or more alkyl substituents;

(iv) by replacement of the phenyl ring with a thienyl ring.]

[F37 (e) Any compound (not being a compound for the time being specified in paragraph 1(ba) of Part 1 of this Schedule) structurally derived from 1-benzofuran, 2,3-dihydro-1-benzofuran, 1H-indole, indoline, 1H-indene, or indane by substitution in the 6-membered ring with a 2-ethylamino substituent whether or not further substituted in the ring system to any extent with alkyl, alkoxy, halide or haloalkyl substituents and whether or not substituted in the ethylamino side-chain with one or more alkyl substituents.]

Textual Amendments

F1 Sch. 2 Pt. 2 para. 1(b) added by S.I. 1984/859, art. 2(3)

F2 Words in Sch. 2 Pt. 2 para. 1(a) inserted (31.5.2017) by The Misuse of Drugs Act 1971 (Amendment) Order 2017 (S.I. 2017/634), art. 4(a)

F3 Word in Sch. 2 Pt. 2 para. 1(a) inserted (13.4.2022) by The Misuse of Drugs Act 1971 (Amendment) Order 2022 (S.I. 2022/322), arts. 1(1), 2(2)(a)

F4 Words in Sch. 2 Pt. 2 para. 1(a) inserted (26.1.2009) by The Misuse of Drugs Act 1971 (Amendment) Order 2008 (S.I. 2008/3130), art. 2(2)(a)

F5 Words in Sch. 2 Pt. 2 para. 1(a) deleted (29.1.2004) by The Misuse of Drugs Act 1971 (Modification) (No. 2) Order 2003 (S.I. 2003/3201), art. 2(3)

F6 Word in Sch. 2 Pt. 2 para. 1(a) inserted (20.3.2024) by The Misuse of Drugs Act 1971 (Amendment) Order 2024 (S.I. 2024/190), arts. 1(1), 2(3)(a)

F7 Word repealed by S.I. 1985/1995, art. 2(2)(a)

F8 Words in Sch. 2 Pt. 2 para. 1(a) inserted (20.3.2024) by The Misuse of Drugs Act 1971 (Amendment) Order 2024 (S.I. 2024/190), arts. 1(1), 2(3)(b)

F9 Words in Sch. 2 Pt. 2 para. 1(a) inserted (31.5.2017) by The Misuse of Drugs Act 1971 (Amendment) Order 2017 (S.I. 2017/634), art. 4(b)

F10 Word in Sch. 2 Pt. 2 para. 1(a) inserted (13.4.2022) by The Misuse of Drugs Act 1971 (Amendment) Order 2022 (S.I. 2022/322), arts. 1(1), 2(2)(b)

F11 Word inserted by S.I. 1985/1995, art. 2(2)(b)

F12 Words in Sch. 2 Pt. 2 para. 1(a) inserted (13.4.2022) by The Misuse of Drugs Act 1971 (Amendment) Order 2022 (S.I. 2022/322), arts. 1(1), 2(2)(c)

F13 Words in Sch. 2 Pt. 2 para. 1(a) inserted (31.5.2017) by The Misuse of Drugs Act 1971 (Amendment) Order 2017 (S.I. 2017/634), art. 4(c)

F14 Word in Sch. 2 Pt. 2 para. 1(a) inserted (10.6.2014) by The Misuse of Drugs Act 1971 (Ketamine etc.) (Amendment) Order 2014 (S.I. 2014/1106), art. 4(a)(i)

F15 Word in Sch. 2 Pt. 2 para. 1(a) inserted (10.6.2014) by The Misuse of Drugs Act 1971 (Ketamine etc.) (Amendment) Order 2014 (S.I. 2014/1106), art. 4(a)(ii)

F16 Word inserted by S.I. 1984/859, art. 2(3)

F17 Words in Sch. 2 Pt. 2 para. 1(a) inserted (1.5.1998) by S.I. 1998/750, art. 2(3)

F18 Word in Sch. 2 Pt. 2 para. 1(a) inserted (20.3.2024) by The Misuse of Drugs Act 1971 (Amendment) Order 2024 (S.I. 2024/190), arts. 1(1), 2(3)(c)

F19 Words in Sch. 2 Pt. 2 para. 1(a) inserted (31.5.2017) by The Misuse of Drugs Act 1971 (Amendment) Order 2017 (S.I. 2017/634), art. 4(d)

F20 Word in Sch. 2 Pt. 2 para. 1(a) omitted (28.3.2011) by virtue of The Misuse of Drugs Act 1971 (Amendment) Order 2011 (S.I. 2011/744), arts. 1(1), 3

F21 Word in Sch. 2 Pt. 2 para. 1(a) repealed (18.1.2007) by The Misuse of Drugs Act 1971 (Amendment) Order 2006 (S.I.2006/3331), art. 2(2)

F22 Word in Sch. 2 Pt. 2 para. 1(a) inserted (1.2.2002) by S.I. 2001/3932, art. 2(3)

F23 Words in Sch. 2 Pt. 2 para. 1(a) inserted (27.11.2017) by The Misuse of Drugs Act 1971 (Amendment) (No. 2) Order 2017 (S.I. 2017/1114), art. 3

F24 Words inserted by S.I. 1973/771, art. 2

F25 Word inserted by S.I. 1985/1995, art. 2(2)(c)

F26 Word inserted by S.I. 1973/771, art. 2

F27 Words in Sch. 2 Pt. 2 para. 1(a) inserted (31.5.2017) by The Misuse of Drugs Act 1971 (Amendment) Order 2017 (S.I. 2017/634), art. 4(e)

F28 Words in Sch. 2 Pt. 2 para. 1(a) inserted (31.5.2017) by The Misuse of Drugs Act 1971 (Amendment) Order 2017 (S.I. 2017/634), art. 4(f)

F29 Words in Sch. 2 Pt. 2 para. 1(a) inserted (26.2.2013) by The Misuse of Drugs Act 1971 (Amendment) Order 2013 (S.I. 2013/239), art. 3

F30 Words in Sch. 2 Pt. 2 para. 1(a) inserted (31.5.2017) by The Misuse of Drugs Act 1971 (Amendment) Order 2017 (S.I. 2017/634), art. 4(g)

F31 Sch. 2 Pt. 2 para. 1(aa) inserted (16.4.2010) by The Misuse of Drugs Act 1971 (Amendment) Order 2010 (S.I. 2010/1207), art. 2(b)

F32 Sch. 2 Pt. 2 para. 1(ab) inserted (23.7.2010) by The Misuse of Drugs Act 1971 (Amendment No. 2) Order 2010 (S.I. 2010/1833), art. 2

F33 Sch. 2 Pt. 2 para. 1(ac) inserted (13.6.2012) by The Misuse of Drugs Act 1971 (Amendment) Order 2012 (S.I. 2012/1390), art. 2(a)

F34 Sch. 2 Pt. 2 para. 1(c)(d) substituted (26.2.2013) for Sch. 2 Pt. 2 para. 1(c) by The Misuse of Drugs Act 1971 (Amendment) Order 2013 (S.I. 2013/239), art. 4

F35 Sch. 2 Pt. 2 para. 1(ca) inserted (14.12.2016) by The Misuse of Drugs Act 1971 (Amendment) Order 2016 (S.I. 2016/1109), arts. 1, 3(a)

F36 Words in Sch. 2 Pt. 2 para. 1(ca) substituted (15.11.2019) by The Misuse of Drugs Act 1971 (Amendment) Order 2019 (S.I. 2019/1323), arts. 1, 2

F37 Sch. 2 Pt. 2 para. 1(e) inserted (10.6.2014) by The Misuse of Drugs Act 1971 (Ketamine etc.) (Amendment) Order 2014 (S.I. 2014/1106), art. 4(b)