The Cosmetic Products (Safety) Regulations 1989

PART I substances listed in annex iii, part i of the directive as substances which cosmetic products must not contain except subject to the restrictions laid down

(1)	(2)	(3)	(4)	(5)	(6)
Reference Number	Name of substance	Purpose of substance or type of product	Maximum concentration of substance in product	Other requirements	Required information
Combination Rules A. Where a cosmetic product contains two or more substances to which this Combination Rule applies, the concentration in the product of each of those substances shall be such that the sum of the relevant quotients for those substances (as defined in Rule C below) shall not exceed 1. B. Where a cosmetic product contains the substances to which this Combination Rule applies, the concentration in the product of each of those substances shall be such that the sum of the relevant quotients for those substances (as defined in Rule C below) shall not exceed 2; but the concentration of each substance shall not in any event exceed the limit specified for the substance in respect of the product in column 4 above. C. The relevant quotient for each substance is the actual concentration of the substance in the product divided by the maximum concentration specified for the substance in respect of the product in Column 4 of this Schedule.
1	Boric acid	Talcum powder	5 per cent	Not to be used in products intended for children less than three years old	Not to be used for children under three years of age
		Oral hygiene products	0.5 per cent	—	—
		Other products	3 per cent	—	—
2	(a) Thioglycollic acid, its salts and esters	Hair waving or straightening products for general use	8 per cent (calculated as thioglycollic acid) ready for use	pH value 7 to 9.5	Contains thioglycollate. Follow the instructions. Keep out of reach of children. For professional use only (where applicable)
		Hair waving or straightening products for professional use	11 per cent (calculated as thioglycollic acid) ready for use	pH value 7 to 9.5
		Depilatories	5 per cent (calculated as thioglycollic acid) ready for use	pH value 7 to 12.7
		Other hair care products which are removed after application	2 per cent (calculated as thioglycollic acid) ready for use	pH value 7 to 9.5 The directions for use drawn up in national or official languages must incorporate the following instructions—Avoid contact with eyes. In the event of contact with the eyes rinse immediately with plenty of water and seek medical advice. Wear suitable gloves (this latter instruction does not apply to Depilatories)
	(b) Thioglycollic acid esters	Hair waving or straightening products for general use	8 per cent (calculated as thioglycollic acid) ready for use	pH value 6 to 9.5
		Hair waving or straightening products for professional use	11 per cent (calculated as thioglycollic acid) ready for use	pH value 6 to 9.5 The directions for use drawn up in national or official languages must incorporate the following instructions—May cause sensitisation in the event of contact with the skin. Avoid contact with eyes. In the event of contact with the eyes rinse immediately with plenty of water and seek medical advice. Wear suitable gloves
3	Oxalic acid, its esters and alkaline salts	Hair care products	5 per cent	—	For professional use only
4	Ammonia	All purposes and products	6 per cent calculated as NH3	—	Contains ammonia (not required when concentration is not more than 2 per cent)
5	Tosylchloramide Sodium	All purposes and products	0.2 per cent	—	—
6	Chlorates of alkali metals	Toothpaste	5 per cent	—	—
		Other uses	3 per cent	—	—
7	Dichloromethane	All purposes and products	35 per cent (and when mixed with 1,1,1-trichloroethane, total concentration must not exceed 35 per cent)	Purity of the dichloromethane must be not less than 99.8 per cent	—
8	m-andp-Phenylenediamines, theirN-substituted derivativesand their salts;N-substituted derivatives ofo-phenylenediamines	Oxidizing colouring agents for hair dyeing for general use	6 per cent calculated as a free base, subject to the provisions of “Combination Rule A” set out below	—	Contains phenylenediamines. Can cause an allergic reaction. Sensitivity test advisable before use. Do not use to dye eyelashes or eyebrows
		Oxidizing colouring agents for hair dyeing for professional use	6 per cent calculated as a free base, subject to the provisions of “Combination Rule A” set out below	—	Contains phenylenediamines. For professional use only. Can cause an allergic reaction. Sensitivity test advisable before use
9	Methylphenylenediamines (other than 4-methyl—m-phenylenediamine and its salts), theirN-substituted derivatives and their salts	Oxidizing colouring agents for hair dyeing for general use	10 per cent calculated as a free base, subject to the provisions of “Combination Rule A” set out below	—	Contains phenylenediamines. Can cause an allergic reaction. Sensitivity test advisable before use. Do not use to dye eyelashes or eyebrows
		Oxidizing colouring agents for hair dyeing for professional use	10 per cent calculated as a free base, subject to the provisions of “Combination Rule A” set out below	—	Contains phenylenediamines. For professional use only. Can cause an allergic reaction. Sensitivity test advisable before use
10	Diaminophenols	Oxidizing colouring agents for hair dyeing for general use	10 per cent calculated as a free base, subject to the provisions of “Combination Rule A” set out below	—	Contains diaminophenols. Can cause an allergic reaction. Sensitivity test advisable before use. Do not use to dye eyelashes or eyebrows
		Oxidizing colouring agents for hair dyeing for professional use	10 per cent calculated as a free base, subject to the provisions of “Combination Rule A” set out below	—	Contains diaminophenols. For professional use only. Can cause allergic reaction. Sensitivity test advisable before use
11	Dichlorophen	All purposes and products	0.5 per cent	—	Contains dichlorophen
12	Hydrogen peroxide	Hair care products preparations	12 per cent of H2O2 (40 volumes)	—	Contains hydrogen peroxide. Avoid contact with eyes. Rinse eyes immediately if product comes into contact with them
		Skin hygiene preparations	4 per cent of H2O2	—	Contains hydrogen peroxide. Avoid contact with eyes. Rinse eyes immediately if product comes into contact with them
		Nail hardening preparations	2 per cent of H2O2	—	Contains hydrogen peroxide. Avoid contact with eyes. Rinse eyes immediately if product comes into contact with them
13	Formaldehyde (See also Part I of Schedule 4)	Nail hardeners	5 per cent	—	Contains formaldehyde. Protect cuticles with grease or oil. (Not required when concentration is not more than 0.05 per cent)
14	Hydroquinone	Oxidizing colouring agent for hair dyeing for general use	2 per cent subject to the provision of “Combination Rule B” set out below	—	Contains hydroquinone. Do not use to dye eyelashes or eyebrows. Rinse eyes immediately if product comes into contact with them
		Oxidizing colouring agent for hair dyeing for professional use	2 per cent subject to the provisions of “Combination Rule B” set out below	—	Contains hydroquinone. For professional use only. Rinse eyes immediately if product comes into contact with them
		Agents for localised skin lightener	2 per cent	—	Contains hydroquinone. Avoid contact with eyes. Apply to small areas. If irritation develops discontinue use. Do not use on children under the age of 12
15	Potassium and sodium hydroxide	Nail cuticle solvent	5 per cent calculated as sodium hydroxide	—	Contains alkali. Avoid contact with eyes. Can cause blindness. Keep out of reach of children
		Hair straightener for general use	2 per cent calculated as sodium hydroxide	—	Contains alkali. Avoid contact with eyes. Can cause blindness. Keep out of reach of children
		Hair straightener for professional use	4.5 per cent calculated as sodium hydroxide	—	For professional use only. Avoid contact with eyes. Can cause blindness
		pH adjuster for depilatories	—	pH value not to exceed 12.7	Keep out of reach of children. Avoid contact with eyes
		Other uses as pH adjuster	—	pH value not to exceed 11	Keep out of reach of children. Avoid contact with eyes
16	α-Naphthol	Colouring agent for hair dyeing	0.5 per cent	—	Contains α-naphthol
17	Sodium nitrite	Rust inhibitor	0.2 per cent	Do not use with secondary and/or tertiary amines or other substances forming nitrosamines	—
18	Nitromethane	Rust inhibitor	0.3 per cent	—	—
19	Phenol and its alkali salts	Soaps and shampoos	1 per cent calculated as phenol	—	Contains phenol
20	Pyrogallol	Oxidizing colouring agent for hair dyeing for general use	5 per cent subject to the provisions of “Combination Rule B” set out below	—	Contains pyrogallol. Do not use to dye eyelashes or eyebrows. Rinse eyes immediately if product comes into contact with them
		Oxidizing colouring agent for hair dyeing for professional use	5 per cent subject to the provisions of “Combination Rule B” set out below	—	Contains pyrogallol. For professional use only. Rinse eyes immediately if product comes into contact with them
21	Quinine and its salts	Shampoos	0.5 per cent calculated as quinine base	—	—
		Hair lotions	0.2 per cent calculated as quinine base	—	—
22	Resorcinol	Oxidizing colouring agent for hair dyeing for general use	5 per cent subject to the provisions of “Combination Rule B” set out below	—	Contains resorcinol. Rinse hair well after application. Do not use to dye eyelashes or eyebrows. Rinse eyes immediately if product comes into contact with them
		Oxidizing colouring agent for hair dyeing for professional use	5 per cent subject to the provisions of “Combination Rule B” set out below	—	Contains resorcinol. For professional use only. Rinse eyes immediately if product comes into contact with them
		Hair lotions and shampoos	0.5 per cent subject to the provisions of “Combination Rule B” set out below	—	Contains resorcinol
23	(a) Alkali sulphides	Depilatories	2 per cent calculated as sulphur	pH value not to exceed 12.7	Keep out of reach of children. Avoid contact with eyes
	(b) Alkaline earth sulphides	Depilatories	6 per cent calculated as sulphur	pH value not to exceed 12.7	Keep out of reach of children. Avoid contact with eyes
24	Water-soluble zinc salts with the exception of zinc 4-hydroxybenzenesulphonate	All purposes and products	1 per cent calculated as zinc	—	—
25	Zinc 4-hydroxybenzenesulphonate	Deodorants, antiperspirants and astringent lotions	6 per cent calculated as percentage of anhydrous substance	—	Avoid contact with eyes
26	Ammonium monofluorophosphate	Oral hygiene products	0.15 per cent calculated as fluorine. When mixed with other fluorine compounds total fluorine concentration must not exceed 0.15 per cent	—	Contains ammonium monofluorophosphate
27	Sodium monofluorophosphate	Oral hygiene products	As for ammonium monofluorophosphate	—	Contains sodium monofluorophosphate
28	Potassium monofluorophosphate	Oral hygiene products	As for ammonium monofluorophosphate	—	Contains potassium monofluorophosphate
29	Calcium monofluorophosphate	Oral hygiene products	As for ammonium monofluorophosphate	—	Contains calcium monofluorophosphate
30	Calcium fluoride	Oral hygiene products	As for ammonium monofluorophosphate	—	Contains calcium fluoride
31	Sodium fluoride	Oral hygiene products	As for ammonium monofluorophosphate	—	Contains sodium fluoride
32	Potassium fluoride	Oral hygiene products	As for ammonium monofluorophosphate	—	Contains potassium fluoride
33	Ammonium fluoride	Oral hygiene products	As for ammonium monofluorophosphate	—	Contains ammonium fluoride
34	Aluminium fluoride	Oral hygiene products	As for ammonium monofluorophosphate	—	Contains aluminium fluoride
35	Stannous fluoride	Oral hygiene products	As for ammonium monofluorophosphate	—	Contains stannous fluoride
36	Hexadecyl ammonium fluoride	Oral hygiene products	As for ammonium monofluorophosphate	—	Contains hexadecyl ammonium fluoride
37	3-(n-Hexadecyl-N-2-hydroxyethylammonio)propyl-bis(2-hydroxyethyl)ammonium difluoride	Oral hygiene products	As for ammonium monofluorophosphate	—	Contains 3-(n-hexadecyl-N-2-hydroxyethylammonio)propyl-bis(2-hydroxyethyl)ammonium difluoride
38	NN'N'-Tris(polyoxyethylene)—N-hexadecylpropylenediamine dihydrofluoride	Oral hygiene products	As for ammonium monofluorophosphate	—	ContainsNN'N'-tris(polyoxyethylene)—N-hexadecylpropylenediamine dihydrofluoride
39	Octadecenyl ammonium fluoride	Oral hygiene products	As for ammonium monofluorophosphate	—	Contains octadecenyl ammonium fluoride
40	Sodium fluorosilicate	Oral hygiene products	As for ammonium monofluorophosphate	—	Contains sodium fluorosilicate
41	Potassium fluorosilicate	Oral hygiene products	As for ammonium monofluorophosphate	—	Contains potassium fluorosilicate
42	Ammonium fluorosilicate	Oral hygiene products	As for ammonium monofluorophosphate	—	Contains ammonium fluorosilicate
43	Magnesium fluorosilicate	Oral hygiene products	As for ammonium monofluorophosphate	—	Contains magnesium fluorosilicate
44	1,3-Bis(hydroxymethyl)-imidazolidene-2-thione	Hair care preparations	2 per cent	Not to be used in aerosol dispensers	Contains 1,3-Bis(hydroxymethyl)imidazoli-dene-2-thione
		Nail care preparations	2 per cent	pH as applied value must be less than 4	Contains 1,3-Bis(hydroxymethyl)imidazoli-dene-2-thione
45	Benzyl alcohol (See also Part I of Schedule 4)	Solvent, perfumes and flavourings	—	—	—
46	6-Methylcoumarin	Oral hygiene products	0.003 per cent	—	—
47	Nicomethanol hydrofluoride	Oral hygiene products	As for ammonium monofluorophosphate	—	Contains nicomethanol hydrofluoride
48	Silver nitrate	Products to dye eyelashes or eyebrows	4 per cent	—	Contains silver nitrate. Rinse eyes immediately if product comes into contact with them
49	Selenium disulphide	Anti-dandruff shampoos	1 per cent	—	Contains selenium disulphide. Avoid contact with eyes or damaged skin
50	Aluminium zirconium chloride hydroxide complexes AlxZr(OH)yCLz and the aluminium zirconium chloride hydroxide glycine complexes	Anti-perspirants	20 per cent as anhydrous aluminium zirconium chloride hydroxide 5.4 per cent as zirconium	The ratio of the number of aluminium atoms to that of zirconium atoms must be betweeen 2 and 10 The ratio of the number of (Al+Zr) atoms to chlorine atoms must be between 0.9 and 2.1 Not to be used in aerosol dispensers (sprays)	Do not apply to irritated or damaged skin
51	Quinolin-8-ol and bis(8-hydroxy-quinolinium sulphate) (See also Part II of this Schedule)	Stabilizer for hydrogen peroxide in rinse-off hair care preparations	0.3 per cent calculated as base	—	—
		Stabilizer for hydrogen peroxide in non-rinse-off hair care preparations	0.03 per cent calculated as base	—	—
52	Methanol	Denaturant for ethanol and isopropyl alcohol	5 per cent calculated as a percentage of ethanol and isopropyl alcohol	—	—
53	Etidronic acid and its salts (1-hydroxy-ethylidene-diphosphonic acid and its salts)	Hair care	1.5 per cent expressed as etidronic acid	—	—
		Soap	0.2 per cent expressed as etidronic acid	—	—
54	1-Phenoxypropan-2-ol (See also Part I of Schedule 4)	Products rinsed off after use. Prohibited in oral hygiene products	2 per cent	—	—