The Good Laboratory Practice Regulations 1997

Biological test systems

10.  Taking account of the relevant aspects referred to above relating to care, housing or containment of biological test systems, the inspector should check that—

• test systems are as specified in study plans,

• test systems are adequately identified,

• animals are adequately and, if necessary and appropriate, uniquely identified throughout the study,

• housing or containers of test systems are properly identified with all the necessary information,

• there is an adequate separation of studies being conducted on the same animal species (or the same biological test system) but with different substances,

• the biological test system environment is as specified in the study plan or in standard operating procedures for aspects such as temperature or light/dark cycles,

• the recording of the receipt, handling, housing or containment, care and health evaluation is appropriate to the test systems,

• written records are kept of examination, quarantine, morbidity, behaviour, diagnosis and treatment of animal and plant test systems or other similar aspects as appropriate to each biological test system,

• there are provisions for the appropriate disposal of test systems at the end of tests.