22. For regulation 42 of the principal Regulations (obligations of manufacturing authorisation holder), substitute—
“42. The holder of a manufacturing authorisation shall—
(a)comply with the principles and guidelines of good manufacturing practice;
(b)comply with the provisions referred to in regulation 40(3);
(c)allow the licensing authority access to his premises at any reasonable time; and
(d)put and keep in place arrangements which enable the qualified person to carry out his duties, including placing at his disposal all the necessary facilities.”.