The Misuse of Drugs Regulations 2001

Regulation 3

SCHEDULE 1 U.K. CONTROLLED DRUGS SUBJECT TO THE REQUIREMENTS OF REGULATIONS 14, 15, 16, 18, 19, 20, 23, 26 AND 27

1.  The following substances and products, namely - U.K.

• [F1 Adinazolam (1-(8-Chloro-6-phenyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepin-1-yl)-N,N-dimethylmethanamine)]

• [F1 N-Benzyl-ethylphenidate]

• [F1 Bromazolam (8-bromo-1-methyl-6-phenyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine)]

• Bufotenine

• Cannabinol

• [F2 Cannabinol derivatives not being—

  (i)

  dronabinol or its stereoisomers; or

  (ii)

  the substance specified in paragraph 10 of Schedule 5]

• Cannabis [F3 (not being the substance specified in paragraph 5 of Part 1 of Schedule 4)] and cannabis resin

• Cathinone

• [F4 4’-Chlorodiazepam (7-Chloro-5-(4-chlorophenyl)-1-methyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one)]

• [F4 Clonazolam (6-(2-Chlorophenyl)-1-methyl-8-nitro-4H-[1,2,4]triazolo[4,3-a][1,4] benzodiazepine)]

• Coca leaf

• Concentrate of poppy-straw

• [F5 Deschloroetizolam (2-Ethyl-9-methyl-4-phenyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4] diazepine)]

• [F5 3,4-Dichloroethylphenidate]

• [F5 3,4-Dichloromethylphenidate (3,4-DCMP)]

• [F5 Diclazepam (7-Chloro-5-(2-chlorophenyl)-1-methyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one)]

• [F6 [2,3–Dihydro–5–methyl–3–(4–morpholinylmethyl)pyrrolo[1, 2, 3–de]–1,4–benzoxazin–6–yl]–1–naphthalenylmethanone]

• [F6 3–Dimethylheptyl–11–hydroxyhexahydrocannabinol]

• [F7 Ethylnaphthidate]

• [F7 Ethylphenidate]

• Eticyclidine

• [F8 Etizolam]

• Etryptamine

• [F9 Flualprazolam (8-chloro-6-(2-fluorophenyl)-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine)]

• [F10 Flubromazepam (7-Bromo-5-(2-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one)]

• [F10 Flubromazolam (8-Bromo-6-(2-fluorophenyl)-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4] benzodiazepine)]

• [F11 Flunitrazolam (6-(2-fluorophenyl)-1-methyl-8-nitro-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine)]

• [F10 4-Fluoroethylphenidate]

• [F10 4-Fluoromethylphenidate]

• [F10 Fonazepam (5-(2-Fluorophenyl)-7-nitro-1,3-dihydro-2H-1,4-benzodiazepin-2-one)]

• [F12 Fungus (of any kind) which contains psilocin or an ester of psilocin]

• [F13 [9–Hydroxy–6–methyl–3–[5–phenylpentan–2–yl] oxy–5, 6, 6a, 7, 8, 9, 10, 10a–octahydrophenanthridin–1–yl] acetate]

• [F13 9-(Hydroxymethyl)–6, 6–dimethyl–3–(2–methyloctan–2–yl)–6a, 7, 10, 10a–tetrahydrobenzo[c]chromen–1–ol]

• [F14 3-Hydroxyphenazepam (7-Bromo-5-(2-chlorophenyl)-3-hydroxy-1,3-dihydro-2H-1,4-benzodiazepin-2-one)]

• [F14 Isopropylphenidate (IPP or IPPD)]

• [F15 Khat]

• Lysergamide

• Lysergide and otherN-alkyl derivatives of lysergamide

• [F16 Meclonazepam (5-(2-Chlorophenyl)-3-methyl-7-nitro-1,3-dihydro-2H-1,4-benzodiazepin-2-one)]

• Mescaline

• Methcathinone

• [F17 4-Methylmethylphenidate]

• [F17 Methylmorphenate]

• [F17 Methylnaphthidate (HDMP-28)]

• [F18 N-methyl-1-(thiophen-2-yl)propan-2-amine (methiopropamine or MPA)]

• [F17 Metizolam (4-(2-Chlorophenyl)-2-ethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]  diazepine)]

• [F17 Nifoxipam (5-(2-Fluorophenyl)-3-hydroxy-7-nitro-1,3-dihydro-2H-1,4-benzodiazepin-2-  one)]

• [F17 Nitrazolam (1-Methyl-8-nitro-6-phenyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine)]

• [F19 Norfludiazepam (7-chloro-5-(2-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one)]

• [F17 Propylphenidate]

• F20 ...

• Psilocin

• [F21 Pyrazolam (8-Bromo-1-methyl-6-(2-pyridinyl)-4H-[1,2,4]triazolo[4,3-a][1,4] benzodiazepine)]

• Raw opium

• Rolicyclidine

• Tenocyclidine

• [F22 (6aR,9R)-4-acetyl-N,N-diethyl-7-methyl-4,6,6a,7,8,9-hexahydroindolo[4,3-fg]quinoline-9-carboxamide (ALD-52)]

• 4-Bromo-2,5-dimethoxy-a-methylphenethylamine

• [F23 1-Cyclohexyl-4-(1,2-diphenylethyl)piperazine (MT-45)]

• [F24 3,4-dichloro-N-[[1-(dimethylamino)cyclohexyl]methyl]benzamide (AH-7921)]

• [F25 3,4-dichloro-N-[2-(dimethylamino)cyclohexyl]-N-methylbenzamide (U-47,700)]

• [F24 (6aR,9R)-N,N-diethyl-7-allyl-4,6,6a,7,8,9-hexahydroindolo[4,3-fg]quinoline-9-carboxamide (AL-LAD)]

• [F24 (6aR,9R)-N,N-diethyl-7-ethyl-4,6,6a,7,8,9-hexahydroindolo[4,3-fg]quinoline-9-carboxamide (ETH-LAD)]

• [F24 (6aR,9R)-N,N-diethyl-7-propyl-4,6,6a,7,8,9-hexahydroindolo[4,3-fg]quinoline-9-carboxamide (PRO-LAD)]

• N,N-Diethyltryptamine

• [F26 2-((Dimethylamino)methyl)-1-(3-hydroxyphenyl)cyclohexanol]

• [F27 2,4-dimethylazetidinyl{(6aR,9R)-7-methyl-4,6,6a,7,8,9-hexahydroindolo[4,3-fg]quinolin-9-yl}methanone (LSZ)]

• N,N-Dimethyltryptamine

• 2,5-Dimethoxy-a,4-dimethylphenethylamine

• N-Hydroxy-tenamphetamine

• 4-Methyl-aminorex

• [F28 4-Methyl-5-(4-methylphenyl)-4,5-dihydrooxazol-2-amine (4,4’-DMAR)]

[F29 (b) any compound (not being a compound for the time being specified in sub-paragraph (a) above) structurally derived from tryptamine or from a ring-hydroxy tryptamine by modification in any of the following ways, that is to say—

(i) by substitution at the nitrogen atom of the sidechain to any extent with alkyl or alkenyl substituents, or by inclusion of the nitrogen atom of the side chain (and no other atoms of the side chain) in a cyclic structure;

(ii) by substitution at the carbon atom adjacent to the nitrogen atom of the side chain with alkyl or alkenyl substituents;

(iii) by substitution in the 6-membered ring to any extent with alkyl, alkoxy, haloalkyl, thioalkyl, alkylenedioxy, or halide substituents;

(iv) by substitution at the 2-position of the tryptamine ring system with an alkyl substituent;]

(c) the following phenethylamine derivatives, namely—

• Allyl(a-methyl-3,4-methylenedioxyphenethyl)amine

• 2-Amino-1-(2,5-dimethoxy-4-methylphenyl)ethanol

• 2-Amino-1-(3,4-dimethoxyphenyl)ethanol

• Benzyl(a-methyl-3,4-methylenedioxyphenethyl)amine

• 4-Bromo-b,2,5-trimethoxyphenethylamine

• N-(4-sec-Butylthio-2,5-dimethoxyphenethyl)hydroxylamine

• Cyclopropylmethyl(a-methyl-3,4-methylenedioxyphenethyl)amine

• 2-(4,7-Dimethoxy-2,3-dihydro-1H-indan-5-yl)ethylamine

• 2-(4,7-Dimethoxy-2,3-dihydro-1H-indan-5-yl)-1-methylethylamine

• 2-(2,5-Dimethoxy-4-methylphenyl)cyclopropylamine

• 2-(1,4-Dimethoxy-2-naphthyl)ethylamine

• 2-(1,4-Dimethoxy-2-naphthyl)-1-methylethylamine

• N-(2,5-Dimethoxy-4-propylthiophenethyl)hydroxylamine

• 2-(1,4-Dimethoxy-5,6,7,8-tetrahydro-2-naphthyl)ethylamine

• 2-(1,4-Dimethoxy-5,6,7,8-tetrahydro-2-naphthyl)-1-methylethylamine

• a,a-Dimethyl-3,4-methylenedioxyphenethylamine

• a,a-Dimethyl-3,4-methylenedioxyphenethyl(methyl)amine

• Dimethyl(a-methyl-3,4-methylenedioxyphenethyl)amine

• N-(4-Ethylthio-2,5-dimethoxyphenethyl)hydroxylamine

• 4-Iodo-2,5-dimethoxy-a-methylphenethyl(dimethyl)amine

• 2-(1,4-Methano-5,8-dimethoxy-1,2,3,4-tetrahydro-6-naphthyl)ethylamine

• 2-(1,4-Methano-5,8-dimethoxy-1,2,3,4-tetrahydro-6-naphthyl)-1-methylethylamine

• 2-(5-Methoxy-2,2-dimethyl-2,3-dihydrobenzo[b]furan-6-yl)-1-methylethylamine

• 2-Methoxyethyl(a-methyl-3,4-methylenedioxyphenethyl)amine

• 2-(5-Methoxy-2-methyl-2,3-dihydrobenzo[b]furan-6-yl)-1-methylethylamine

• b-Methoxy-3,4-methylenedioxyphenethylamine

• 1-(3,4-Methylenedioxybenzyl)butyl(ethyl)amine

• 1-(3,4-Methylenedioxybenzyl)butyl(methyl)amine

• 2-(a-Methyl-3,4-methylenedioxyphenethylamino)ethanol

• a-Methyl-3,4-methylenedioxyphenethyl(prop-2-ynyl)amine

• N-Methyl-N-(a-methyl-3,4-methylenedioxyphenethyl)hydroxylamine

• O-Methyl-N-(a-methyl-3,4-methylenedioxyphenethyl)hydroxylamine

• a-Methyl-4-(methylthio)phenethylamine

• b,3,4,5-Tetramethoxyphenethylamine

• b,2,5-Trimethoxy-4-methylphenethylamine

(d) any compound (not being methoxyphenamine or a compound for the time being specified in sub-paragraph (a) above) structurally derived from phenethylamine, anN-alkylphenethylamine,a-methylphenethylamine, anN-alkyl-a-methylphenethylamine,a-ethylphenethylamine, or anN-alkyl-a-ethylphenethylamine by substitution in the ring to any extent with alkyl, alkoxy, alkylenedioxy or halide substitutents, whether or not further substituted in the ring by one or more other univalent substituents;

(e) any compound (not being a compound for the time being specified in Schedule 2) structurally derived from fentanyl by modification in any of the following ways, that is to say -

(i) by replacement of the phenyl portion of the phenethyl group by any heteromonocycle whether or not further substituted in the heterocycle;

(ii) by substitution in the phenethyl group with alkyl, alkenyl, alkoxy, hydroxy, halogeno, haloalkyl, amino or nitro groups;

(iii) by substitution in the piperidine ring with alkyl or alkenyl groups;

(iv) by substitution in the aniline ring with alkyl, alkoxy, alkylenedioxy, halogeno or haloalkyl groups;

(v) by substitution at the 4-position of the piperidine ring with any alkoxycarbonyl or alkoxyalkyl or acyloxy group;

(vi) by replacement of theN-propionyl group by another acyl group;

(f) any compound (not being a compound for the time being specified in Schedule 2) structurally derived from pethidine by modification in any of the following ways, that is to say—

(i) by replacement of the l-methyl group by an acyl, alkyl whether or not unsaturated, benzyl or phenethyl group, whether or not further substituted;

(ii) by substitution in the piperidine ring with alkyl or alkenyl groups or with a propano bridge, whether or not further substituted;

(iii) by substitution in the 4-phenyl ring with alkyl, alkoxy, aryloxy, halogeno or haloalkyl groups;

(iv) by replacement of the 4-ethoxycarbonyl by any other alkoxycarbonyl or any alkoxyalkyl or acyloxy group;

(v) by formation of an N-oxide or of a quaternary base.

[F30 (g) 1–benzylpiperazine or any compound (not being a compound for the time being specified in Schedule 4) structurally derived from 1–benzylpiperazine or 1–phenylpiperazine by modification in any of the following ways—

(i) by substitution at the second nitrogen atom of the piperazine ring with alkyl, benzyl, haloalkyl or phenyl groups;

(ii) by substitution in the aromatic ring to any extent with alkyl, alkoxy, alkylenedioxy, halide or haloalkyl groups;

[F31 (h) Any compound structurally derived from 3–(1–naphthoyl)indole, 3-(2-naphthoyl)indole, 1H–indol–3–yl–(1–naphthyl)methane or 1H-indol-3-yl-(2-naphthyl)methane by substitution at the nitrogen atom of the indole ring by alkyl, haloalkyl, alkenyl, cyanoalkyl, hydroxyalkyl, cycloalkylmethyl, cycloalkylethyl, (N-methylpiperidin-2-yl)methyl or 2–(4–morpholinyl)ethyl, whether or not further substituted in the indole ring to any extent and whether or not substituted in the naphthyl ring to any extent.

(i) Any compound structurally derived from 3–(1–naphthoyl)pyrrole or 3-(2-naphthoyl)pyrrole by substitution at the nitrogen atom of the pyrrole ring by alkyl, haloalkyl, alkenyl, cyanoalkyl, hydroxyalkyl, cycloalkylmethyl, cycloalkylethyl, (N-methylpiperidin-2-yl)methyl or 2–(4–morpholinyl)ethyl, whether or not further substituted in the pyrrole ring to any extent and whether or not substituted in the naphthyl ring to any extent.

(j) Any compound structurally derived from 1–(1–naphthylmethylene)indene or 1-(2-naphthylmethylene)indene by substitution at the 3–position of the indene ring by alkyl, haloalkyl, alkenyl, cyanoalkyl, hydroxyalkyl, cycloalkylmethyl, cycloalkylethyl, (N-methylpiperidin-2-yl)methyl or 2–(4–morpholinyl)ethyl, whether or not further substituted in the indene ring to any extent and whether or not substituted in the naphthyl ring to any extent.

(k) Any compound structurally derived from 3–phenylacetylindole by substitution at the nitrogen atom of the indole ring by alkyl, haloalkyl, alkenyl, cyanoalkyl, hydroxyalkyl, cycloalkylmethyl, cycloalkylethyl, (N-methylpiperidin-2-yl)methyl or 2–(4–morpholinyl)ethyl, whether or not further substituted in the indole ring to any extent and whether or not substituted in the phenyl ring to any extent.]

(l) any compound structurally derived from 2–(3–hydroxycyclohexyl)phenol by substitution at the 5–position of the phenolic ring by alkyl, alkenyl, cycloalkylmethyl, cycloalkylethyl or 2–(4–morpholinyl)ethyl, whether or not further substituted in the cyclohexyl ring to any extent.]

[F32 (la) Any compound structurally derived from 3-benzoylindole by substitution at the nitrogen atom of the indole ring by alkyl, haloalkyl, alkenyl, cyanoalkyl, hydroxyalkyl, cycloalkylmethyl, cycloalkylethyl, (N-methylpiperidin-2-yl)methyl or 2–(4–morpholinyl)ethyl, whether or not further substituted in the indole ring to any extent and whether or not substituted in the phenyl ring to any extent.

(lb) Any compound structurally derived from 3-(1-adamantoyl)indole or 3-(2-adamantoyl)indole by substitution at the nitrogen atom of the indole ring by alkyl, haloalkyl, alkenyl, cyanoalkyl, hydroxyalkyl, cycloalkylmethyl, cycloalkylethyl, (N-methylpiperidin-2-yl)methyl or 2–(4–morpholinyl)ethyl, whether or not further substituted in the indole ring to any extent and whether or not substituted in the adamantyl ring to any extent.

(lc) Any compound structurally derived from 3-(2,2,3,3-tetramethylcyclopropylcarbonyl)indole by substitution at the nitrogen atom of the indole ring by alkyl, haloalkyl, alkenyl, cyanoalkyl, hydroxyalkyl, cycloalkylmethyl, cycloalkylethyl, (N-methylpiperidin-2-yl)methyl or 2–(4–morpholinyl)ethyl, whether or not further substituted in the indole ring to any extent.]

[F33 (ld) [F34 Any compound (not being a compound for the time being specified in sub-paragraphs (h) to (lc) above) structurally related to 1-pentyl-3-(1-naphthoyl)indole (JWH-018), in that the four sub-structures, that is to say the indole ring, the pentyl substituent, the methanone linking group and the naphthyl ring, are linked together in a similar manner, whether or not any of the sub-structures have been modified, and whether or not substituted in any of the linked sub-structures with a benzyl or phenyl group and whether or not such compound is further substituted to any extent with alkyl, alkenyl, alkoxy, halide, haloalkyl or cyano substituents and, where any of the sub-structures have been modified, the modifications of the sub-structures are limited to any of the following, that is to say—]

(i) replacement of the indole ring with indane, indene, indazole, pyrrole, pyrazole, imidazole, benzimidazole, pyrrolo[2,3-b]pyridine, pyrrolo[3,2-c]pyridine or pyrazolo[3,4‑b]pyridine;

(ii) replacement of the pentyl substituent with alkyl, alkenyl, benzyl, cycloalkylmethyl, cycloalkylethyl, (N-methylpiperidin-2-yl)methyl, 2-(4-morpholinyl)ethyl or (tetrahydropyran-4-yl)methyl;

(iii) replacement of the methanone linking group with an ethanone, carboxamide, carboxylate, methylene bridge or methine group;

(iv) replacement of the 1-naphthyl ring with 2-naphthyl, phenyl, benzyl, adamantyl, cycloalkyl, cycloalkylmethyl, cycloalkylethyl, bicyclo[2.2.1]heptanyl, 1,2,3,4-tetrahydronaphthyl, quinolinyl, isoquinolinyl, 1-amino-1-oxopropan-2-yl, 1‑hydroxy-1-oxopropan-2-yl, piperidinyl, morpholinyl, pyrrolidinyl, tetrahydropyranyl or piperazinyl;]

[F35 (m) Any compound (not being bupropion, diethylpropion, pyrovalerone or a compound for the time being specified in sub–paragraph (a) above) structurally derived from 2–amino–1–phenyl–1–propanone by modification in any of the following ways, that is to say—

(i) by substitution in the phenyl ring to any extent with alkyl, alkoxy, alkylenedioxy, haloalkyl or halide substituents, whether or not further substituted in the phenyl ring by one or more other univalent substituents;

(ii) by substitution at the 3–position with an alkyl substituent;

(iii) by substitution at the nitrogen atom with alkyl or dialkyl groups, or by inclusion of the nitrogen atom in a cyclic structure.]

[F36 (n) Any compound structurally derived from 2–aminopropan–1–one by substitution at the 1‑position with any monocyclic, or fused‑polycyclic ring system (not being a phenyl ring or alkylenedioxyphenyl ring system), whether or not the compound is further modified in any of the following ways, that is to say—

(i) by substitution in the ring system to any extent with alkyl, alkoxy, haloalkyl or halide substituents, whether or not further substituted in the ring system by one or more other univalent substituents;

(ii) by substitution at the 3–position with an alkyl substituent;

(iii) by substitution at the 2‑amino nitrogen atom with alkyl or dialkyl groups, or by inclusion of the 2‑amino nitrogen atom in a cyclic structure.]

[F37 (o) Any compound (not being pipradrol) structurally derived from piperidine, pyrrolidine, azepane, morpholine or pyridine by substitution at a ring carbon atom with a diphenylmethyl group, whether or not the compound is further modified in any of the following ways, that is to say,

(i) by substitution in any of the phenyl rings to any extent with alkyl, alkoxy, haloalkyl or halide groups;

(ii) by substitution at the methyl carbon atom with an alkyl, hydroxyalkyl or hydroxy group;

(iii) by substitution at the ring nitrogen atom with an alkyl, alkenyl, haloalkyl or hydroxyalkyl group.]

[F38 (p) 1-Phenylcyclohexylamine or any compound (not being eticyclidine, ketamine, phencyclidine, rolicyclidine, tenocyclidine or tiletamine) structurally derived from 1-phenylcyclohexylamine or 2-amino-2-phenylcyclohexanone by modification in any of the following ways, that is to say,

(i) by substitution at the nitrogen atom to any extent by alkyl, alkenyl or hydroxyalkyl groups, or replacement of the amino group with a 1-piperidyl, 1-pyrrolidyl or 1-azepyl group, whether or not the nitrogen containing ring is further substituted by one or more alkyl groups;

(ii) by substitution in the phenyl ring to any extent by amino, alkyl, hydroxy, alkoxy or halide substituents, whether or not further substituted in the phenyl ring to any extent;

(iii) by substitution in the cyclohexyl or cyclohexanone ring by one or more alkyl substituents;

(iv) by replacement of the phenyl ring with a thienyl ring.]

[F39 (q) Any compound (not being benzyl(α-methyl-3,4-methylenedioxyphenethyl)amine) structurally derived from mescaline, 4-bromo-2,5-dimethoxy-α-methylphenethylamine, 2,5-dimethoxy-α,4-dimethylphenethylamine, N-hydroxytenamphetamine, or a compound specified in sub-paragraph (c) or (d) above, by substitution at the nitrogen atom of the amino group with a benzyl substituent, whether or not substituted in the phenyl ring of the benzyl group to any extent;

(r) Any compound (not being a compound for the time being specified in sub- paragraph (c) above) structurally derived from 1-benzofuran, 2,3-dihydro-1-benzofuran, 1H-indole, indoline, 1H-indene, or indane by substitution in the 6-membered ring with a 2-ethylamino substituent whether or not further substituted in the ring system to any extent with alkyl, alkoxy, halide or haloalkyl substituents and whether or not substituted in the ethylamino side-chain with one or more alkyl substituents.]

Textual Amendments

F1 Words in Sch. 1 para. 1(a) inserted (31.5.2017) by The Misuse of Drugs (Amendment) (England, Wales and Scotland) Regulations 2017 (S.I. 2017/631), regs. 1(1), 3(a)

F2 Words in Sch. 1 para. 1(a) substituted (24.6.2020) by The Misuse of Drugs (Amendment) (England, Wales and Scotland) Regulations 2020 (S.I. 2020/559), regs. 1(1), 2(3)

F3 Words in Sch. 1 para. 1(a) inserted (10.4.2013) by The Misuse of Drugs (Amendment No. 2) (England, Wales and Scotland) Regulations 2013 (S.I. 2013/625), regs. 1(1), 6

F4 Words in Sch. 1 para. 1(a) inserted (31.5.2017) by The Misuse of Drugs (Amendment) (England, Wales and Scotland) Regulations 2017 (S.I. 2017/631), regs. 1(1), 3(b)

F5 Words in Sch. 1 para. 1(a) inserted (31.5.2017) by The Misuse of Drugs (Amendment) (England, Wales and Scotland) Regulations 2017 (S.I. 2017/631), regs. 1(1), 3(c)

F6 Words in Sch. 1 para. 1(a) inserted (23.12.2009) by The Misuse of Drugs (Amendment) (England, Wales and Scotland) Regulations 2009 (S.I. 2009/3136), regs. 1(1), 4(1)(a)(i)

F7 Words in Sch. 1 para. 1(a) inserted (31.5.2017) by The Misuse of Drugs (Amendment) (England, Wales and Scotland) Regulations 2017 (S.I. 2017/631), regs. 1(1), 3(d)

F8 Word in Sch. 1 para. 1(a) inserted (31.5.2017) by The Misuse of Drugs (Amendment) (England, Wales and Scotland) Regulations 2017 (S.I. 2017/631), regs. 1(1), 3(e)

F9 Words in Sch. 1 para. 1(a) inserted (18.8.2021) by The Misuse of Drugs and Misuse of Drugs (Designation) (Amendment) (England, Wales and Scotland) Regulations 2021 (S.I. 2021/897), regs. 1(2), 2(2)(a)

F10 Words in Sch. 1 para. 1(a) inserted (31.5.2017) by The Misuse of Drugs (Amendment) (England, Wales and Scotland) Regulations 2017 (S.I. 2017/631), regs. 1(1), 3(f)

F11 Words in Sch. 1 para. 1(a) inserted (18.8.2021) by The Misuse of Drugs and Misuse of Drugs (Designation) (Amendment) (England, Wales and Scotland) Regulations 2021 (S.I. 2021/897), regs. 1(2), 2(2)(b)

F12 Words in Sch. 1 para. 1(a) inserted (18.7.2005) by The Misuse of Drugs (Amendment) (No. 2) Regulations 2005 (S.I. 2005/1653), regs. 1, 2(3)

F13 Words in Sch. 1 para. 1(a) inserted (23.12.2009) by The Misuse of Drugs (Amendment) (England, Wales and Scotland) Regulations 2009 (S.I. 2009/3136), regs. 1(1), 4(1)(a)(ii)

F14 Words in Sch. 1 para. 1(a) inserted (31.5.2017) by The Misuse of Drugs (Amendment) (England, Wales and Scotland) Regulations 2017 (S.I. 2017/631), regs. 1(1), 3(g)

F15 Word in Sch. 1 para. 1(a) inserted (24.6.2014) by The Misuse of Drugs (Amendment) (England, Wales and Scotland) Regulations 2014 (S.I. 2014/1377), regs. 1(1), 3

F16 Words in Sch. 1 para. 1(a) inserted (31.5.2017) by The Misuse of Drugs (Amendment) (England, Wales and Scotland) Regulations 2017 (S.I. 2017/631), regs. 1(1), 3(h)

F17 Words in Sch. 1 para. 1(a) inserted (31.5.2017) by The Misuse of Drugs (Amendment) (England, Wales and Scotland) Regulations 2017 (S.I. 2017/631), regs. 1(1), 3(i)

F18 Words in Sch. 1 para. 1(a) inserted (27.11.2017) by The Misuse of Drugs (Amendment) (No. 2) (England, Wales and Scotland) Regulations 2017 (S.I. 2017/1117), regs. 1(1), 3

F19 Words in Sch. 1 para. 1(a) inserted (18.8.2021) by The Misuse of Drugs and Misuse of Drugs (Designation) (Amendment) (England, Wales and Scotland) Regulations 2021 (S.I. 2021/897), regs. 1(2), 2(2)(c)

F20 Word in Sch. 1 para. 1(a) omitted (28.3.2011) by virtue of The Misuse of Drugs (Amendment) (England, Wales and Scotland) Regulations 2011 (S.I. 2011/448), regs. 1(1), 4

F21 Words in Sch. 1 para. 1(a) inserted (31.5.2017) by The Misuse of Drugs (Amendment) (England, Wales and Scotland) Regulations 2017 (S.I. 2017/631), regs. 1(1), 3(j)

F22 Words in Sch. 1 para. 1(a) inserted (7.1.2015) by The Misuse of Drugs (Amendment No. 3) (England, Wales and Scotland) Regulations 2014 (S.I. 2014/3277), regs. 1(1), 3(a)

F23 Words in Sch. 1 para. 1(a) inserted (11.3.2015) by The Misuse of Drugs (Amendment) (England, Wales and Scotland) Regulations 2015 (S.I. 2015/231), regs. 1(1), 3(a)

F24 Words in Sch. 1 para. 1(a) inserted (7.1.2015) by The Misuse of Drugs (Amendment No. 3) (England, Wales and Scotland) Regulations 2014 (S.I. 2014/3277), regs. 1(1), 3(b)

F25 Words in Sch. 1 para. 1(a) inserted (31.5.2017) by The Misuse of Drugs (Amendment) (England, Wales and Scotland) Regulations 2017 (S.I. 2017/631), regs. 1(1), 3(k)

F26 Words in Sch. 1 para. 1(a) inserted (26.2.2013) by The Misuse of Drugs (Amendment) (England, Wales and Scotland) Regulations 2013 (S.I. 2013/176), regs. 1(1), 3

F27 Words in Sch. 1 para. 1(a) inserted (7.1.2015) by The Misuse of Drugs (Amendment No. 3) (England, Wales and Scotland) Regulations 2014 (S.I. 2014/3277), regs. 1(1), 3(c)

F28 Words in Sch. 1 para. 1(a) inserted (11.3.2015) by The Misuse of Drugs (Amendment) (England, Wales and Scotland) Regulations 2015 (S.I. 2015/231), regs. 1(1), 3(b)

F29 Sch. 1 para. 1(b) substituted (7.1.2015) by The Misuse of Drugs (Amendment No. 3) (England, Wales and Scotland) Regulations 2014 (S.I. 2014/3277), regs. 1(1), 4

F30 Sch. 1 para. 1(g)-(l) inserted (23.12.2009) by The Misuse of Drugs (Amendment) (England, Wales and Scotland) Regulations 2009 (S.I. 2009/3136), regs. 1(1), 4(1)(b)

F31 Sch. 1 para. 1(h)-(k) substituted (26.2.2013) by The Misuse of Drugs (Amendment) (England, Wales and Scotland) Regulations 2013 (S.I. 2013/176), regs. 1(1), 4

F32 Sch. 1 para. 1(la)-(lc) inserted (26.2.2013) by The Misuse of Drugs (Amendment) (England, Wales and Scotland) Regulations 2013 (S.I. 2013/176), regs. 1(1), 5

F33 Sch. 1 para. 1(ld) inserted (14.12.2016) by The Misuse of Drugs (Amendment) (England, Wales and Scotland) Regulations 2016 (S.I. 2016/1125), regs. 1(1), 2(2)

F34 Words in Sch. 1 para. 1(ld) substituted (15.11.2019) by The Misuse of Drugs and Misuse of Drugs (Designation) (Amendment) (England, Wales and Scotland) Regulations 2019 (S.I. 2019/1362), regs. 1(1), 2

F35 Sch. 1 para. 1(m) inserted (16.4.2010) by The Misuse of Drugs (Amendment) (England, Wales and Scotland) Regulations 2010 (S.I. 2010/1144), regs. 1(1), 3(b)

F36 Sch. 1 para. 1(n) inserted (23.7.2010) by The Misuse of Drugs (Amendment No.2) (England, Wales and Scotland) Regulations 2010 (S.I. 2010/1799), regs. 1(1), 3

F37 Sch. 1 para. 1(o) inserted (13.6.2012) by The Misuse of Drugs (Amendment No.3) (England, Wales and Scotland) Regulations 2012 (S.I. 2012/1311), regs. 1(1), 3

F38 Sch. 1 para. 1(p) inserted (26.2.2013) by The Misuse of Drugs (Amendment) (England, Wales and Scotland) Regulations 2013 (S.I. 2013/176), regs. 1(1), 6

F39 Sch. 1 para. 1(q)(r) inserted (10.6.2014) by The Misuse of Drugs and Misuse of Drugs (Safe Custody) (Amendment) (England, Wales and Scotland) Regulations 2014 (S.I. 2014/1275), regs. 1(1), 3

2.  Any stereoisomeric form of a substance specified in paragraph 1. U.K.

[F40 3.   Any ester or ether of a substance specified in paragraph 1 (not being 2-((dimethylamino)methyl)-1-(3-hydroxyphenyl)cyclohexanol) or paragraph 2.] U.K.

Textual Amendments

F40 Sch. 1 para. 3 substituted (26.2.2013) by The Misuse of Drugs (Amendment) (England, Wales and Scotland) Regulations 2013 (S.I. 2013/176), regs. 1(1), 7

4.  Any salt of a substance specified in any of paragraphs 1 to 3. U.K.

5.  Any preparation or other product containing a substance or product specified in any of paragraphs 1 to 4, not being a preparation specified in Schedule 5. U.K.

[F41 6.   But paragraphs 1 to 5 do not include a cannabis-based product for medicinal use in humans.] U.K.

Textual Amendments

F41 Sch. 1 para. 6 inserted (1.11.2018) by The Misuse of Drugs (Amendments) (Cannabis and Licence Fees) (England, Wales and Scotland) Regulations 2018 (S.I. 2018/1055), regs. 1(1), 6

Regulation 3

SCHEDULE 2 U.K. CONTROLLED DRUGS SUBJECT TO THE REQUIREMENTS OF REGULATIONS 14, 15, 16, [F42 16A,] 18, 19, 20, 21, 23, 26 AND 27

Textual Amendments

F42 Word in Sch. 2 heading inserted (1.11.2018) by The Misuse of Drugs (Amendments) (Cannabis and Licence Fees) (England, Wales and Scotland) Regulations 2018 (S.I. 2018/1055), regs. 1(1), 7(a)

1.  The following substances and products, namely— U.K.

• Acetorphine

• Alfentanil

• Allylprodine

• Alphacetylmethadol

• Alphameprodine

• Alphamethadol

• Alphaprodine

• [F43 Amineptine]

• Anileridine

• Benzethidine

• Benzylmorphine (3-benzylmorphine)

• Betacetylmethadol

• Betameprodine

• Betamethadol

• Betaprodine

• Bezitramide

• [F44 Cannabis-based product for medicinal use in humans]

• Carfentanil

• Clonitazene

• Cocaine

• Desomorphine

• Dextromoramide

• Diamorphine

• Diampromide

• Diethylthiambutene

• Difenoxin

• Dihydrocodeinone O-carboxymethyloxime

• [F45 Dihydroetorphine]

• Dihydromorphine

• Dimenoxadole

• Dimepheptanol

• Dimethylthiambutene

• Dioxaphetyl butyrate

• Diphenoxylate

• Dipipanone

• Dronabinol

• Drotebanol

• Ecgonine, and any derivative of ecgonine which is convertible to ecgonine or to cocaine

• Ethylmethylthiambutene

• Etonitazene

• Etorphine

• Etoxeridine

• Fentanyl

• Furethidine

• Hydrocodone

• Hydromorphinol

• Hydromorphone

• [F46 4-Hydroxy-n-butyric acid]

• Hydroxypethidine

• Isomethadone

• [F47 Ketamine]

• Ketobemidone

• Levomethorphan

• Levomoramide

• Levophenacylmorphan

• Levorphanol

• [F48 Lisdexamphetamine]

• Lofentanil

• Medicinal opium

• Metazocine

• Methadone

• Methadyl acetate

• Methyldesorphine

• Methyldihydromorphine (6-methyldihydromorphine)

• Metopon

• Morpheridine

• Morphine

• Morphine methobromide, morphine N-oxide and other pentavalent nitrogen morphine derivatives

• Myrophine

• [F49 Nabilone]

• Nicomorphine

• Noracymethadol

• Norlevorphanol

• Normethadone

• Normorphine

• Norpipanone

• [F50 Oripavine]

• Oxycodone

• Oxymorphone

• Pethidine

• Phenadoxone

• Phenampromide

• Phenazocine

• Phencyclidine

• Phenomorphan

• Phenoperidine

• Piminodine

• Piritramide

• Proheptazine

• Properidine

• Racemethorphan

• Racemoramide

• Racemorphan

• [F51 Remifentanil]

• Sufentanil

• [F52 Tapentadol]

• Thebacon

• Thebaine

• Tilidate

• Trimeperidine

• Zipeprol

• 4-Cyano-2-dimethylamino-4,4-diphenylbutane

• 4-Cyano-1-methyl-4-phenylpiperidine

• 2-Methyl-3-morpholino-1,1-diphenylpropane-carboxylic acid

• a-Methylphenethylhydroxylamine

• 1-Methyl-4-phenylpiperidine-4-carboxylic acid

• 4-Phenylpiperidine-4-carboxylic acid ethyl ester

Textual Amendments

F43 Word in Sch. 2 para. 1 inserted (28.3.2011) by The Misuse of Drugs (Amendment) (England, Wales and Scotland) Regulations 2011 (S.I. 2011/448), regs. 1(1), 5(a)

F44 Words in Sch. 2 para. 1 inserted (1.11.2018) by The Misuse of Drugs (Amendments) (Cannabis and Licence Fees) (England, Wales and Scotland) Regulations 2018 (S.I. 2018/1055), regs. 1(1), 7(b)

F45 Word in Sch. 2 para. 1 inserted (1.7.2003) by The Misuse of Drugs (Amendment) Regulations 2003 (S.I. 2003/1432), regs. 1, 2(2)(a)

F46 Words in Sch. 2 para. 1 inserted (7.1.2015) by The Misuse of Drugs (Amendment No. 3) (England, Wales and Scotland) Regulations 2014 (S.I. 2014/3277), regs. 1(1), 5

F47 Word in Sch. 2 para. 1 inserted (30.11.2015) by The Misuse of Drugs (Amendment) (No. 2) (England, Wales and Scotland) Regulations 2015 (S.I. 2015/891), regs. 1(3), 17

F48 Word in Sch. 2 para. 1 inserted (10.6.2014) by The Misuse of Drugs and Misuse of Drugs (Safe Custody) (Amendment) (England, Wales and Scotland) Regulations 2014 (S.I. 2014/1275), regs. 1(1), 4

F49 Word in Sch. 2 para. 1 inserted (23.12.2009) by The Misuse of Drugs (Amendment) (England, Wales and Scotland) Regulations 2009 (S.I. 2009/3136), regs. 1(1), 4(2)(a)

F50 Word in Sch. 2 para. 1 inserted (23.12.2009) by The Misuse of Drugs (Amendment) (England, Wales and Scotland) Regulations 2009 (S.I. 2009/3136), regs. 1(1), 4(2)(b)

F51 Word in Sch. 2 para. 1 inserted (1.7.2003) by The Misuse of Drugs (Amendment) Regulations 2003 (S.I. 2003/1432), regs. 1, 2(2)(b)

F52 Word in Sch. 2 para. 1 inserted (28.3.2011) by The Misuse of Drugs (Amendment) (England, Wales and Scotland) Regulations 2011 (S.I. 2011/448), regs. 1(1), 5(b)

2.  Any stereoisomeric form of a substance specified in paragraph 1 not being dextromethorphan or dextrorphan. U.K.

3.  Any ester or ether of a substance specified in paragraph 1 or 2, not being a substance specified in paragraph 6. U.K.

4.  Any salt of a substance specified in any of paragraphs 1 to 3. U.K.

5.  Any preparation or other product containing a substance or product specified in any of paragraphs 1 to 4, not being a preparation specified in Schedule 5. U.K.

[F53 5A.   But paragraphs 2 to 5 only apply in respect of a cannabis-based product for medicinal use in humans if the cannabis-based product that would, as a consequence of paragraphs 2 to 5, be specified in this Schedule but for the operation of this paragraph, is produced for medicinal use in humans.] U.K.

Textual Amendments

F53 Sch. 2 para. 5A inserted (1.11.2018) by The Misuse of Drugs (Amendments) (Cannabis and Licence Fees) (England, Wales and Scotland) Regulations 2018 (S.I. 2018/1055), regs. 1(1), 7(c)

6.  The following substances and products, namely— U.K.

Acetyldihydrocodeine	Methaqualone
Amphetamine	Methylamphetamine
Codeine	Methylphenidate
Dextropropoxyphene	Nicocodine
Dihydrocodeine	Nicodicodine (6-nicotinoyldihydrocodeine)
Ethylmorphine (3-ethylmorphine)	Norcodeine
Fenethylline	Phenmetrazine
Glutethimide	Pholcodine
Lefetamine	Propiram
Mecloqualone	Quinalbarbitone

7.  Any stereoisomeric form of a substance specified in paragraph 6. U.K.

8.  Any salt of a substance specified in paragraph 6 or 7. U.K.

9.  Any preparation or other product containing a substance or product specified in any of paragraphs 6 to 8, not being a preparation specified in Schedule 5. U.K.

Regulation 3

SCHEDULE 3 U.K. CONTROLLED DRUGS SUBJECT TO THE REQUIREMENTS OF REGULATIONS 14, 15 F54 ..., 16, 18, 22, 23, 24, 26 AND 27

Textual Amendments

F54 Words in Sch. 3 heading omitted (1.6.2015) by virtue of The Misuse of Drugs (Amendment) (No. 2) (England, Wales and Scotland) Regulations 2015 (S.I. 2015/891), regs. 1(1), 18

1.  The following substances, namely— U.K.

(a)  

• Benzphetamine

• [F55 7-bromo-5-(2-chlorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one]

• Buprenorphine

• Cathine

• Chlorphentermine

• Diethylpropion

• Ethchlorvynol

• Ethinamate

• Flunitrazepam

• [F56 Gabapentin (1–(aminomethyl)cyclohexaneacetic acid)]

• Mazindol

• Mephentermine

• Meprobamate

• Methylphenobarbitone

• Methyprylone

• [F57 Midazolam]

• Pentazocine

• Phendimetrazine

• Phentermine

• Pipradrol

• [F58 Pregabalin ((S)–3–(aminomethyl)-5-methylhexanoic acid)]

• Temazepam

• [F59 Tramadol]

(b) any 5, 5 disubstituted barbituric acid not being quinalbarbitone.

Textual Amendments

F55 Words in Sch. 3 para. 1(a) inserted (13.6.2012) by The Misuse of Drugs (Amendment No.3) (England, Wales and Scotland) Regulations 2012 (S.I. 2012/1311), regs. 1(1), 4

F56 Words in Sch. 3 para. 1(a) inserted (1.4.2019) by The Misuse of Drugs and Misuse of Drugs (Safe Custody) (Amendment) (England and Wales and Scotland) Regulations 2018 (S.I. 2018/1383), regs. 1(1), 2(2)(a)

F57 Word in Sch. 3 para. 1(a) inserted (1.1.2008) by The Misuse of Drugs and Misuse of Drugs (Safe Custody) (Amendment) Regulations 2007 (S.I. 2007/2154), regs. 2(3)(e), 4(14)

F58 Words in Sch. 3 para. 1(a) inserted (1.4.2019) by The Misuse of Drugs and Misuse of Drugs (Safe Custody) (Amendment) (England and Wales and Scotland) Regulations 2018 (S.I. 2018/1383), regs. 1(1), 2(2)(b)

F59 Word in Sch. 3 para. 1(a) inserted (10.6.2014) by The Misuse of Drugs and Misuse of Drugs (Safe Custody) (Amendment) (England, Wales and Scotland) Regulations 2014 (S.I. 2014/1275), regs. 1(1), 5

[F60 2.   Any stereoisomeric form of a substance specified in paragraph 1 or 3 not being phenylpropanolamine. U.K.

Textual Amendments

F60 Sch. 3 paras. 2-5 substituted for Sch. 3 paras. 2-4 (13.6.2012) by The Misuse of Drugs (Amendment No.3) (England, Wales and Scotland) Regulations 2012 (S.I. 2012/1311), regs. 1(1), 5

3.   [F61 Any—

(a) ester or ether of pipradrol; or

(b) ester of gabapentin (1–(aminomethyl)cyclohexaneacetic acid) or pregabalin ((S)–3–(aminomethyl)-5-methylhexanoic acid).]

Textual Amendments

F60 Sch. 3 paras. 2-5 substituted for Sch. 3 paras. 2-4 (13.6.2012) by The Misuse of Drugs (Amendment No.3) (England, Wales and Scotland) Regulations 2012 (S.I. 2012/1311), regs. 1(1), 5

F61 Words in Sch. 3 para. 3 substituted (1.4.2019) by The Misuse of Drugs and Misuse of Drugs (Safe Custody) (Amendment) (England and Wales and Scotland) Regulations 2018 (S.I. 2018/1383), regs. 1(1), 2(3)

4.   Any salt of a substance specified in any of paragraphs 1 to 3. U.K.

Textual Amendments

F60 Sch. 3 paras. 2-5 substituted for Sch. 3 paras. 2-4 (13.6.2012) by The Misuse of Drugs (Amendment No.3) (England, Wales and Scotland) Regulations 2012 (S.I. 2012/1311), regs. 1(1), 5

5.   Any preparation or other product containing a substance specified in any of paragraphs 1 to 4, not being a preparation specified in Schedule 5.] U.K.

Textual Amendments

F60 Sch. 3 paras. 2-5 substituted for Sch. 3 paras. 2-4 (13.6.2012) by The Misuse of Drugs (Amendment No.3) (England, Wales and Scotland) Regulations 2012 (S.I. 2012/1311), regs. 1(1), 5

Regulation 3

SCHEDULE 4 U.K.

PART I U.K. CONTROLLED DRUGS SUBJECT TO THE REQUIREMENTS OF REGULATIONS 22, 23, 26 AND 27

1.  The following substances and products, namely— U.K.

• Alprazolam

• Aminorex

• Bromazepam

• Brotizolam

• Camazepam

• Chlordiazepoxide

• [F62 1–(3–chlorophenyl)piperazine]

• [F62 1–(3–chlorophenyl)–4–(3–chloropropyl)piperazine]

• Clobazam

• Clonazepam

• Clorazepic acid

• Clotiazepam

• Cloxazolam

• Delorazepam

• Diazepam

• Estazolam

• Ethyl loflazepate

• Fencamfamin

• Fenproporex

• Fludiazepam

• Flurazepam

• Halazepam

• Haloxazolam

• F63 ...

• F64 ...

• Ketazolam

• Loprazolam

• Lorazepam

• Lormetazepam

• Medazepam

• Mefenorex

• Mesocarb

• F65 ...

• Nimetazepam

• Nitrazepam

• Nordazepam

• Oxazepam

• Oxazolam

• Pemoline

• Pinazepam

• Prazepam

• Pyrovalerone

• Tetrazepam

• Triazolam

• N-Ethylamphetamine

• [F66 Zaleplon]

• [F67 Zolpidem]

• [F68 Zopiclone]

Textual Amendments

F62 Words in Sch. 4 Pt. 1 para. 1 inserted (23.12.2009) by The Misuse of Drugs (Amendment) (England, Wales and Scotland) Regulations 2009 (S.I. 2009/3136), regs. 1(1), 4(3)

F63 Words in Sch. 4 Pt. 1 para. 1 omitted (7.1.2015) by virtue of The Misuse of Drugs (Amendment No. 3) (England, Wales and Scotland) Regulations 2014 (S.I. 2014/3277), regs. 1(1), 6

F64 Word in Sch. 4 Pt. 1 para. 1 omitted (30.11.2015) by virtue of The Misuse of Drugs (Amendment) (No. 2) (England, Wales and Scotland) Regulations 2015 (S.I. 2015/891), regs. 1(3), 19

F65 Word in Sch. 4 Pt. 1 para. 1 omitted (1.1.2008) by virtue of The Misuse of Drugs and Misuse of Drugs (Safe Custody) (Amendment) Regulations 2007 (S.I. 2007/2154), regs. 2(3)(e), 4(13)

F66 Word in Sch. 4 Pt. 1 para. 1 inserted (10.6.2014) by The Misuse of Drugs and Misuse of Drugs (Safe Custody) (Amendment) (England, Wales and Scotland) Regulations 2014 (S.I. 2014/1275), regs. 1(1), 6(a)

F67 Word in Sch. 4 Pt. 1 para. 1 inserted (1.7.2003) by The Misuse of Drugs (Amendment) Regulations 2003 (S.I. 2003/1432), regs. 1, 2(3)(b)

F68 Word in Sch. 4 Pt. 1 para. 1 inserted (10.6.2014) by The Misuse of Drugs and Misuse of Drugs (Safe Custody) (Amendment) (England, Wales and Scotland) Regulations 2014 (S.I. 2014/1275), regs. 1(1), 6(b)

2.  Any stereoisomeric form of a substance specified in paragraph 1. U.K.

3.  Any salt of a substance specified in paragraph 1 or 2. U.K.

4.  Any preparation or other product containing a substance or product specified in any of paragraphs 1 to 3, not being a preparation specified in Schedule 5. U.K.

[F69 5.   A liquid formulation— U.K.

(a) containing a botanical extract of cannabis—

(i) with a concentration of not more than 30 milligrams of cannabidiol per millilitre, and not more than 30 milligrams of delta-9-tetrahydrocannabinol per millilitre, and

(ii) where the ratio of cannabidiol to delta-9-tetrahydrocannabinol is between 0.7 and 1.3,

(b) which is dispensed through a metered dose pump as a mucosal mouth spray, and

(c) which was approved for marketing by the Medicines and Healthcare Products Regulatory Agency on 16^th June 2010]

Textual Amendments

F69 Sch. 4 Pt. 1 para. 5 inserted (10.4.2013) by The Misuse of Drugs (Amendment No. 2) (England, Wales and Scotland) Regulations 2013 (S.I. 2013/625), regs. 1(1), 7

PART II U.K. [F70 Controlled Drugs Excepted From the Prohibition on Possession; Excluded from the Application of Offences Arising from the Prohibition on Importation and Exportation when Carried Out in Person for Administration to That Person; and Subject to the Requirements of Regulations 22, 23, 26 and 27]

Textual Amendments

F70 Sch. 4 Pt. 2 heading substituted (23.4.2012) by The Misuse of Drugs (Amendment No.2) (England, Wales and Scotland) Regulations 2012 (S.I. 2012/973), regs. 1(1), 15

1.  The following substances, namely— U.K.

• [F71 5α–Androstane–3,17–diol]

• [F71 Androst-4-ene-3,17-diol]

• [F71 1–Androstenediol]

• [F71 1–Androstenedione]

• [F72 4-Androstene-3, 17-dione]

• [F73 5–Androstenedione]

• [F72 5-Androstene-3, 17 diol]

• Atamestane

• Bolandiol

• Bolasterone

• Bolazine

• Boldenone

• [F74 Boldione]

• Bolenol

• Bolmantalate

• Calusterone

• 4-Chloromethandienone

• Clostebol

• [F75 Danazol]

• [F75 Desoxymethyltestosterone]

• [F76 Dienedione (estra-4, 9-diene-3,17-dione)]

• Drostanolone

• Enestebol

• Epitiostanol

• Ethyloestrenol

• Fluoxymesterone

• Formebolone

• Furazabol

• [F77 Gestrinone]

• [F77 3–Hydroxy–5α–androstan–17–one]

• Mebolazine

• Mepitiostane

• Mesabolone

• Mestanolone

• Mesterolone

• Methandienone

• Methandriol

• Methenolone

• Methyltestosterone

• Metribolone

• Mibolerone

• Nandrolone

• [F78 19–Norandrostenedione]

• [F79 19-Nor-4-Androstene-3, 17-dione]

• [F79 19-Nor-5-Androstene-3, 17 diol]

• [F80 19–Norandrosterone]

• Norboletone

• Norclostebol

• Norethandrolone

• [F81 19–Noretiocholanolone]

• Ovandrotone

• Oxabolone

• Oxandrolone

• Oxymesterone

• Oxymetholone

• Prasterone

• Propetandrol

• [F82 Prostanozol]

• Quinbolone

• Roxibolone

• Silandrone

• Stanolone

• Stanozolol

• Stenbolone

• Testosterone

• [F83 Tetrahydrogestrinone]

• Thiomesterone

• Trenbolone

Textual Amendments

F71 Words in Sch. 4 Pt. 2 para. 1 inserted (23.12.2009) by The Misuse of Drugs (Amendment) (England, Wales and Scotland) Regulations 2009 (S.I. 2009/3136), regs. 1(1), 4(4)(a)(i)

F72 Words in Sch. 4 Pt. 2 para. 1 inserted (1.7.2003) by The Misuse of Drugs (Amendment) Regulations 2003 (S.I. 2003/1432), regs. 1, 2(4)(a)

F73 Words in Sch. 4 Pt. 2 para. 1 inserted (23.12.2009) by The Misuse of Drugs (Amendment) (England, Wales and Scotland) Regulations 2009 (S.I. 2009/3136), regs. 1(1), 4(4)(a)(ii)

F74 Words in Sch. 4 Pt. 2 para. 1 inserted (23.12.2009) by The Misuse of Drugs (Amendment) (England, Wales and Scotland) Regulations 2009 (S.I. 2009/3136), regs. 1(1), 4(4)(a)(iii)

F75 Words in Sch. 4 Pt. 2 para. 1 inserted (23.12.2009) by The Misuse of Drugs (Amendment) (England, Wales and Scotland) Regulations 2009 (S.I. 2009/3136), regs. 1(1), 4(4)(a)(iv)

F76 Word in Sch. 4 Pt. 2 para. 1 inserted (14.12.2016) by The Misuse of Drugs (Amendment) (England, Wales and Scotland) Regulations 2016 (S.I. 2016/1125), regs. 1(1), 2(3)

F77 Words in Sch. 4 Pt. 2 para. 1 inserted (23.12.2009) by The Misuse of Drugs (Amendment) (England, Wales and Scotland) Regulations 2009 (S.I. 2009/3136), regs. 1(1), 4(4)(a)(v)

F78 Words in Sch. 4 Pt. 2 para. 1 inserted (23.12.2009) by The Misuse of Drugs (Amendment) (England, Wales and Scotland) Regulations 2009 (S.I. 2009/3136), regs. 1(1), 4(4)(a)(vi)

F79 Words in Sch. 4 Pt. 2 para. 1 inserted (1.7.2003) by The Misuse of Drugs (Amendment) Regulations 2003 (S.I. 2003/1432), regs. 1, 2(4)(b)

F80 Words in Sch. 4 Pt. 2 para. 1 inserted (23.12.2009) by The Misuse of Drugs (Amendment) (England, Wales and Scotland) Regulations 2009 (S.I. 2009/3136), regs. 1(1), 4(4)(a)(vii)

F81 Words in Sch. 4 Pt. 2 para. 1 inserted (23.12.2009) by The Misuse of Drugs (Amendment) (England, Wales and Scotland) Regulations 2009 (S.I. 2009/3136), regs. 1(1), 4(4)(a)(viii)

F82 Words in Sch. 4 Pt. 2 para. 1 inserted (23.12.2009) by The Misuse of Drugs (Amendment) (England, Wales and Scotland) Regulations 2009 (S.I. 2009/3136), regs. 1(1), 4(4)(a)(ix)

F83 Words in Sch. 4 Pt. 2 para. 1 inserted (23.12.2009) by The Misuse of Drugs (Amendment) (England, Wales and Scotland) Regulations 2009 (S.I. 2009/3136), regs. 1(1), 4(4)(a)(x)

2.  Any compound (not being Trilostane or a compound for the time being specified in paragraph 1 of this Part of this Schedule) structurally derived from 17-hydroxyandrostan-3-one or from 17-hydroxyestran-3-one by modification in any of the following ways, that is to say - U.K.

(a) by further substitution at position 17 by a methyl or ethyl group;

(b) by substitution to any extent at one or more of positions 1, 2, 4, 6, 7, 9, 11 or 16, but at no other position;

(c) by unsaturation in the carbocyclic ring system to any extent, provided that there are no more than two ethylenic bonds in any one carbocyclic ring;

(d) by fusion of ring A with a heterocyclic system.

3.  Any substance which is an ester or ether (or, where more than one hydroxyl function is available, both an ester and an ether) of a substance specified in paragraph 1 or described in paragraph 2 of this Part of this Schedule. U.K.

4.  The following substances, namely— U.K.

• Chorionic Gonadotrophin (HCG)

• Clenbuterol

• Non-human chorionic gonadotrophin

• Somatotropin

• Somatrem

• Somatropin

• [F84 Zeranol]

• [F84 Zilpaterol]

Textual Amendments

F84 Words in Sch. 4 Pt. 2 para. 4 inserted (23.12.2009) by The Misuse of Drugs (Amendment) (England, Wales and Scotland) Regulations 2009 (S.I. 2009/3136), regs. 1(1), 4(4)(b)

5.  Any stereoisomeric form of a substance specified or described in any of paragraphs 1 to 4 of this Part of this Schedule. U.K.

6.  Any salt of a substance specified or described in any of paragraphs 1 to 5 of this Part of this Schedule. U.K.

7.  Any preparation or other product containing a substance or product specified or described in any of paragraphs 1 to 6 of this Part of this Schedule, not being a preparation specified in Schedule 5. U.K.

Regulation 3

SCHEDULE 5 U.K. CONTROLLED DRUGS EXCEPTED FROM THE PROHIBITION ON IMPORTATION, EXPORTATION AND POSSESSION [F85 (APART FROM NITROUS OXIDE)] AND SUBJECT TO THE REQUIREMENTS OF REGULATIONS 24 AND 26

Textual Amendments

F85 Words in Sch. 5 heading inserted (8.11.2023) by The Misuse of Drugs (England and Wales and Scotland) (Amendment) Regulations 2023 (S.I. 2023/1099), regs. 1(1), 8(a)

1.—(1) Any preparation of one or more of the substances to which this paragraph applies, not being a preparation designed for administration by injection, when compounded with one or more other active or inert ingredients and containing a total of not more than 100 milligrams of the substance or substances (calculated as base) per dosage unit or with a total concentration of not more than 2.5% (calculated as base) in undivided preparations. U.K.

(2) The substances to which this paragraph applies are acetyldihydrocodeine, codeine, dihydrocodeine, ethylmorphine, nicocodine, nicodicodine (6-nicotinoyldihydrocodeine), norcodeine and pholcodine and their respective salts.

F86 2.  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . U.K.

Textual Amendments

F86 Sch. 5 para. 2 revoked (14.11.2005) by The Misuse of Drugs and the Misuse of Drugs (Supply to Addicts) (Amendment) Regulations 2005 (S.I. 2005/2864), regs. 1(1), 13

3.  Any preparation of medicinal opium or of morphine containing (in either case) not more than 0.2% of morphine calculated as anhydrous morphine base, being a preparation compounded with one or more other active or inert ingredients in such a way that the opium or, as the case may be, the morphine cannot be recovered by readily applicable means or in a yield which would constitute a risk to health. U.K.

4.  Any preparation of dextropropoxyphene, being a preparation designed for oral administration, containing not more than 135 milligrams of dextropropoxyphene (calculated as base) per dosage unit or with a total concentration of not more than 2.5% (calculated as base) in undivided preparations. U.K.

5.  Any preparation of difenoxin containing, per dosage unit, not more than 0.5 milligrams of difenoxin and a quantity of atropine sulphate equivalent to at least 5% of the dose of difenoxin. U.K.

6.  Any preparation of diphenoxylate containing, per dosage unit, not more than 2.5 milligrams of diphenoxylate calculated as base, and a quantity of atropine sulphate equivalent to at least 1% of the dose of diphenoxylate. U.K.

7.  Any preparation of propiram containing, per dosage unit, not more than 100 milligrams of propiram calculated as base and compounded with at least the same amount (by weight) of methylcellulose. U.K.

8.  Any powder of ipecacuanha and opium comprising— U.K.

• 10% opium, in powder,

• 10% ipecacuanha root, in powder, well mixed with

• 80% of any other powdered ingredient containing no controlled drug.

9.  Any mixture containing one or more of the preparations specified in paragraphs 1 to 8, being a mixture of which none of the other ingredients is a controlled drug. U.K.

[F87 10.   A liquid formulation— U.K.

(a) containing cannabidiol obtained by extraction and purification from cannabis;

(b) where the concentration of—

(i) delta-9-tetrahydrocannabinol is not more than 0.1 milligram per millilitre; and

(ii) cannabidiol is 95-105 milligrams per millilitre;

(c) which is presented in a bottle, as an oral solution for oral administration; and

(d) which was approved for marketing by the European Commission on 19th September 2019. ]

Textual Amendments

F87 Sch. 5 para. 10 inserted (24.6.2020) by The Misuse of Drugs (Amendment) (England, Wales and Scotland) Regulations 2020 (S.I. 2020/559), regs. 1(1), 2(4)

[F88 11.   Nitrous oxide.] U.K.

Textual Amendments

F88 Sch. 5 para. 11 inserted (8.11.2023) by The Misuse of Drugs (England and Wales and Scotland) (Amendment) Regulations 2023 (S.I. 2023/1099), regs. 1(1), 8(b)

Regulation 19

F89 SCHEDULE 6 U.K. FORM OF REGISTER

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Textual Amendments

F89 Sch. 6 revoked (1.2.2008) by The Misuse of Drugs and Misuse of Drugs (Safe Custody) (Amendment) Regulations 2007 (S.I. 2007/2154), regs. 2(4)(b), 4(15)

Regulation 28

SCHEDULE 7 U.K. REGULATIONS REVOKED

Regulations revoked	References
The Misuse of Drugs Regulations 1985	S.I. 1985/2066
The Misuse of Drugs (Amendment) Regulations 1986	S.I. 1986/2330
The Misuse of Drugs (Amendment) Regulations 1988	S.I. 1988/916
The Misuse of Drugs (Amendment) Regulations 1989	S.I. 1989/1460
The Misuse of Drugs (Amendment) Regulations 1990	S.I. 1990/2630
The Misuse of Drugs (Amendment) Regulations 1995	S.I. 1995/2048
The Misuse of Drugs (Amendment No. 2) Regulations 1995	S.I. 1995/3244
The Misuse of Drugs (Amendment) Regulations 1996	S.I. 1996/1597
The Misuse of Drugs (Amendment) Regulations 1998	S.I. 1998/882
The Misuse of Drugs (Amendment) Regulations 1999	S.I. 1999/1404

[F91 Regulations 6(2), 8(8), 9(8) and 10(2)]

[F90 SCHEDULE 8 U.K.

Textual Amendments

F90 Sch. 8 inserted (15.10.2003) by The Misuse of Drugs (Amendment) (No. 3) Regulations 2003 (S.I. 2003/2429), reg. 1, Sch.

F91 Sch. 8 reference note substituted (23.4.2012) by The Misuse of Drugs (Amendment No.2) (England, Wales and Scotland) Regulations 2012 (S.I. 2012/973), regs. 1(1), 16

1.   Any of the following persons may supply or administer a specified controlled drug under a patient group direction, namely— U.K.

(a) a person who holds a certificate of proficiency in ambulance paramedic skills issued by, or with the approval of, the Secretary of State, or a person who is a F92 ... registered paramedic;

F93 (b) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

(c) a registered midwife;

[F94 (d) a registered optometrist;

(e) a registered chiropodist;

(f) a registered orthoptist;

(g) a registered physiotherapist;

(h) a registered radiographer;]

[F95 (i) a registered occupational therapist;

(j) a registered orthotist and prosthetist;]

[F96 (k) a pharmacist]];

Textual Amendments

F92 Word in Sch. 8 para. 1(a) revoked (16.8.2007) by The Misuse of Drugs and Misuse of Drugs (Safe Custody) (Amendment) Regulations 2007 (S.I. 2007/2154), regs. 2(1), 4(16)(a)

F93 Sch. 8 para. 1(b) omitted (1.8.2004) by virtue of The Health Act 1999 (Consequential Amendments) (Nursing and Midwifery) Order 2004 (S.I. 2004/1771), art. 1(1), Sch. para. 24(d)

F94 Sch. 8 para. 1(d)-(h) substituted (16.8.2007) by The Misuse of Drugs and Misuse of Drugs (Safe Custody) (Amendment) Regulations 2007 (S.I. 2007/2154), regs. 2(1), 4(16)(b)

F95 Sch. 8 para. 1(i)(j) inserted (7.7.2006) by The Misuse of Drugs (Amendment No. 2) Regulations 2006 (S.I. 2006/1450), regs. 2(1), 11 (with regs. 12, 13)

F96 Sch. 8 para. 1(k) inserted (23.4.2012) by The Misuse of Drugs (Amendment No.2) (England, Wales and Scotland) Regulations 2012 (S.I. 2012/973), regs. 1(1), 16