The Blood Safety and Quality Regulations 2005

Deferral criteria for donors of whole blood and blood components

2.1.  Permanent deferral criteria for donors of allogeneic donations

Cardiovascular disease	Prospective donors with active or past serious cardiovascular disease, except congenital abnormalities with complete cure
Central nervous system disease	A history of serious CNS disease
Abnormal bleeding tendency	Prospective donors who give a history of a coagulopathy
Repeated episodes of syncope, or a history of convulsions	Other than childhood convulsions or where at least three years have elapsed since the date the donor last took anticonvulsant medication without any recurrence of convulsions
Gastrointestinal. Genitourinary, haematological, immunological, metabolic, renal, or respiratory system diseases	Prospective donors with serious active, chronic, or relapsing disease
Diabetes	If being treated with insulin
Infectious diseases	Hepatitis B, except for HBsAg-negative persons who are demonstrated to be immune
	Hepatitis C
	HIV – 1 and 2
	HTLV I/II
	Babesiosis (*)
	Kala Azar (visceral leishmaniasis) (*)
	Trypanosomiasis cruzi (Chagas' disease) (*)
Malignant diseases	Except in situ cancer with complete recovery
Transmissible spongiform encephalopathies (TSEs) (e.g. Creutzfeldt Jakob Disease, variant Creutzfeldt Jakob Disease)	Persons who have a family history which places them at risk of developing a TSE, or persons who have received a corneal or dura mater graft, or who have been treated in the past with medicines made from human pituitary glands. For variant Creutzfeldt Jacob disease, further precautionary measures may be recommended.
Intravenous (IV) or intramuscular (IM) drug use	Any history of non-prescribed IV or IM drug use, including body-building steroids or hormones
Xenotransplant recipients
Sexual behaviour	Persons whose sexual behaviour puts them at high risk of acquiring severe infectious diseases that can be transmitted by blood